ES2341646T3 - Composiciones y metodos para administrar farmacos fotosensibles. - Google Patents

Composiciones y metodos para administrar farmacos fotosensibles. Download PDF

Info

Publication number
ES2341646T3
ES2341646T3 ES03727053T ES03727053T ES2341646T3 ES 2341646 T3 ES2341646 T3 ES 2341646T3 ES 03727053 T ES03727053 T ES 03727053T ES 03727053 T ES03727053 T ES 03727053T ES 2341646 T3 ES2341646 T3 ES 2341646T3
Authority
ES
Spain
Prior art keywords
nanoparticles
nanoparticle
photosensitizer
nanoparticle according
lactide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES03727053T
Other languages
English (en)
Spanish (es)
Inventor
Eric Allemann
Yvette Konan
Robert Gurny
Ronald Erwin Boch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novelion Therapeutics Inc
Original Assignee
QLT Inc
Quadra Logic Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by QLT Inc, Quadra Logic Technologies Inc filed Critical QLT Inc
Application granted granted Critical
Publication of ES2341646T3 publication Critical patent/ES2341646T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES03727053T 2002-05-16 2003-05-16 Composiciones y metodos para administrar farmacos fotosensibles. Expired - Lifetime ES2341646T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38147402P 2002-05-16 2002-05-16
US381474P 2002-05-16

Publications (1)

Publication Number Publication Date
ES2341646T3 true ES2341646T3 (es) 2010-06-24

Family

ID=29550129

Family Applications (1)

Application Number Title Priority Date Filing Date
ES03727053T Expired - Lifetime ES2341646T3 (es) 2002-05-16 2003-05-16 Composiciones y metodos para administrar farmacos fotosensibles.

Country Status (8)

Country Link
US (1) US7455858B2 (de)
EP (1) EP1503796B1 (de)
AT (1) ATE456956T1 (de)
AU (1) AU2003233287A1 (de)
CA (1) CA2484664C (de)
DE (1) DE60331185D1 (de)
ES (1) ES2341646T3 (de)
WO (1) WO2003097096A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003000226A2 (en) * 2001-06-22 2003-01-03 Pfizer Products Inc. Pharmaceutical compositions containing polymer and drug assemblies
US7133547B2 (en) 2002-01-24 2006-11-07 Tripath Imaging, Inc. Method for quantitative video-microscopy and associated system and computer software program product
WO2005095950A1 (en) * 2004-03-30 2005-10-13 Pfizer Products Inc. Method and device for evaluation of pharmaceutical compositions
US20060222592A1 (en) * 2005-04-05 2006-10-05 Clemens Burda Nanoparticles and methods of manufacturing nanoparticles for electronic and non-electronic applications
WO2006133271A2 (en) * 2005-06-06 2006-12-14 The General Hospital Corporation Compositions and methods relating to target-specific photodynamic therapy
US20100119827A1 (en) * 2006-04-25 2010-05-13 Research Foundation Of The City University Of New York Polymer submicron particle preparation by surfactant-mediated precipitation
WO2008065502A1 (en) * 2006-11-29 2008-06-05 Pfizer Products Inc. Pharmaceutical compositions based on a) nanoparticles comprising enteric polymers and b) casein
US20100119612A1 (en) * 2007-04-17 2010-05-13 Bend Research, Inc Nanoparticles comprising non-crystalline drug
US8703204B2 (en) * 2007-05-03 2014-04-22 Bend Research, Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
US20100080852A1 (en) * 2007-05-03 2010-04-01 Ronald Arthur Beyerinck Phamaceutical composition comprising nanoparticles and casein
WO2008135828A2 (en) * 2007-05-03 2008-11-13 Pfizer Products Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
WO2008149230A2 (en) 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate
EP2162120B1 (de) * 2007-06-04 2016-05-04 Bend Research, Inc Nanopartikel mit nicht ionisierbarem zellulosepolymer und amphipilem nicht ionisierbarem blockcopolymer
US20100215747A1 (en) * 2007-07-13 2010-08-26 Corey Jay Bloom Nanoparticles comprising ionizable, poorly water soluble cellulosic polymers
WO2009073215A1 (en) * 2007-12-06 2009-06-11 Bend Research, Inc. Pharmaceutical compositions comprising nanoparticles and a resuspending material
EP2240162A4 (de) * 2007-12-06 2013-10-09 Bend Res Inc Nanoteilchen mit einem nicht-ionisierbaren polymer und einem amin-funktionalisierten methacrylat-copolymer
EP2153821A1 (de) * 2008-08-06 2010-02-17 BioAlliance Pharma Orale Formulierungen von Camptothecin-Derivaten
EP2198885B1 (de) 2008-12-19 2012-02-08 Biolitec AG Kalziumphosphat-Nanopartikel als Farbstoffträger für die photodynamische Therapie
US8815931B2 (en) * 2009-04-28 2014-08-26 Biolitec Pharma Marketing Ltd Oral formulations for tetrapyrrole derivatives
US20110275686A1 (en) 2009-12-11 2011-11-10 Biolitec, Inc. Nanoparticle carrier systems based on poly(dl-lactic-co-glycolic acid) (plga) for photodynamic therapy (pdt)
US9211283B2 (en) * 2009-12-11 2015-12-15 Biolitec Pharma Marketing Ltd Nanoparticle carrier systems based on human serum albumin for photodynamic therapy
EP2741775B1 (de) * 2011-08-11 2017-01-04 Quest Pharmatech Inc. Polymernanopartikel für photosensibilisatoren
EP2996677B1 (de) * 2013-05-18 2019-11-20 National Chung-Hsing University Fotosensibilisatorteilchen für die medizinische bildgebung und/oder fotodynamische therapie
WO2015195458A1 (en) * 2014-06-17 2015-12-23 Albert Einstein College Of Medicine, Inc. Therapeutic nanoparticles and methods thereof
WO2016054079A1 (en) 2014-09-29 2016-04-07 Zyomed Corp. Systems and methods for blood glucose and other analyte detection and measurement using collision computing
WO2017015471A1 (en) 2015-07-21 2017-01-26 Avedro, Inc. Systems and methods for treaments of an eye with a photosensitizer
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4883790A (en) 1987-01-20 1989-11-28 University Of British Columbia Wavelength-specific cytotoxic agents
US4968350A (en) 1987-04-16 1990-11-06 Christian Bindschaedler Process for preparing a powder of water-insoluble polymer which can be redispersed in a liquid phase, the resulting powder and utilization thereof
US5798349A (en) 1994-03-14 1998-08-25 The General Hospital Corporation Use of green porphyrins to treat neovasculature in the eye
US5707608A (en) * 1995-08-02 1998-01-13 Qlt Phototherapeutics, Inc. Methods of making liposomes containing hydro-monobenzoporphyrin photosensitizer
CA2229285A1 (en) 1995-09-21 1997-03-27 Robert Gurny Nanoparticles in photodynamic therapy
US20020127224A1 (en) 2001-03-02 2002-09-12 James Chen Use of photoluminescent nanoparticles for photodynamic therapy

Also Published As

Publication number Publication date
WO2003097096A1 (en) 2003-11-27
DE60331185D1 (de) 2010-03-25
CA2484664A1 (en) 2003-11-27
US20040047913A1 (en) 2004-03-11
EP1503796B1 (de) 2010-02-03
ATE456956T1 (de) 2010-02-15
EP1503796A1 (de) 2005-02-09
CA2484664C (en) 2010-07-06
US7455858B2 (en) 2008-11-25
AU2003233287A1 (en) 2003-12-02

Similar Documents

Publication Publication Date Title
US7455858B2 (en) Compositions and methods for delivery of photosensitive drugs
Konan-Kouakou et al. In vitro and in vivo activities of verteporfin-loaded nanoparticles
Konan et al. Enhanced photodynamic activity of meso-tetra (4-hydroxyphenyl) porphyrin by incorporation into sub-200 nm nanoparticles
Vargas et al. Improved photodynamic activity of porphyrin loaded into nanoparticles: an in vivo evaluation using chick embryos
JP4800922B2 (ja) 光線力学療法用の治療薬を封入するためのセラミックベースナノ粒子及びその使用方法
JP5154296B2 (ja) 疎水性薬物のための薬物送達系
US20070148074A1 (en) Nanoparticle based stabilization of ir fluorescent dyes
KR101892785B1 (ko) 감광제를 위한 폴리머 나노입자
US9211283B2 (en) Nanoparticle carrier systems based on human serum albumin for photodynamic therapy
US8815931B2 (en) Oral formulations for tetrapyrrole derivatives
Duong et al. Phototheranostic nanoplatform based on a single cyanine dye for image-guided combinatorial phototherapy
Pegaz et al. Photothrombic activity of m-THPC-loaded liposomal formulations: pre-clinical assessment on chick chorioallantoic membrane model
ES2304429T3 (es) Terapia fotodinamica con indice de fluencia reducido.
Vargas et al. In vivo photodynamic activity of photosensitizer-loaded nanoparticles: formulation properties, administration parameters and biological issues involved in PDT outcome
US20060159740A1 (en) Hydrophobic photosensitizer formulations for photodynamic therapy
JPH11502520A (ja) 難水溶性の光増感性化合物の投与に適した乳濁液及びその使用
HUP0000576A2 (hu) A zöld porfirinek alkalmazása szekunder szürkehályogok kezelésére alkalmas gyógyszerek készítésében
Li et al. Liposomal hypocrellin B as a potential photosensitizer for age-related macular degeneration: pharmacokinetics, photodynamic efficacy, and skin phototoxicity in vivo
Pegaz et al. Effect of nanoparticle size on the extravasation and the photothrombic activity of meso (p-tetracarboxyphenyl) porphyrin
US20210228719A1 (en) Triplet-triplet energy transfer with light excitation at long wavelengths and methods thereof
de Toledo et al. Zinc phthalocyanine tetrasulfonate-loaded polyelectrolytic PLGA nanoparticles for photodynamic therapy applications
Lim et al. The neovessel occlusion efficacy of 151‐hydroxypurpurin‐7‐lactone dimethyl ester induced with photodynamic therapy
Shakiba et al. Porphyrin nanoparticles in photomedicine
US20250114372A1 (en) Composition comprising photosensitzer compound and activation thereof
DE60225844T2 (de) Micelle-zusammensetzungen enthaltend pegylierten phospholipide und einen photosensibilisator