ES2421598T3 - Composición glucopeptídica con actividad antibiótica mejorada - Google Patents
Composición glucopeptídica con actividad antibiótica mejoradaInfo
- Publication number
- ES2421598T3 ES2421598T3 ES04762852T ES04762852T ES2421598T3 ES 2421598 T3 ES2421598 T3 ES 2421598T3 ES 04762852 T ES04762852 T ES 04762852T ES 04762852 T ES04762852 T ES 04762852T ES 2421598 T3 ES2421598 T3 ES 2421598T3
- Authority
- ES
- Spain
- Prior art keywords
- glucopeptide
- composition
- antibiotic activity
- improved antibiotic
- glycopeptides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000003115 biocidal effect Effects 0.000 title abstract 2
- 102000002068 Glycopeptides Human genes 0.000 abstract 2
- 108010015899 Glycopeptides Proteins 0.000 abstract 2
- 239000003910 polypeptide antibiotic agent Substances 0.000 abstract 2
- MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
Composición antibiótica glucopeptídica apropiada para la administración como medicamento a un paciente y quecomprende: A: un antibiótico glucopeptídico en su forma glucosilada; y B: un resto de un antibiótico glucopeptídico que carece de una o varias unidades de glucosilo; siendo elcontenido de B de 14% a 73% (p/p) del contenido total de glucopéptidos y glucopéptidos desglucosilados,calculado como: 10 B / (A + B) (p/p).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03021000A EP1516626B1 (en) | 2003-09-17 | 2003-09-17 | A Teicoplanin composition with improved antibiotic activity |
| PCT/DK2004/000632 WO2005025599A1 (en) | 2003-09-17 | 2004-09-17 | A glycopeptide composition with improved antibiotic activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2421598T3 true ES2421598T3 (es) | 2013-09-04 |
Family
ID=34178422
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES03021000T Expired - Lifetime ES2278101T3 (es) | 2003-09-17 | 2003-09-17 | Composicion de teicoplanina con actividad antibiotica mejorada. |
| ES04762852T Expired - Lifetime ES2421598T3 (es) | 2003-09-17 | 2004-09-17 | Composición glucopeptídica con actividad antibiótica mejorada |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES03021000T Expired - Lifetime ES2278101T3 (es) | 2003-09-17 | 2003-09-17 | Composicion de teicoplanina con actividad antibiotica mejorada. |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US7981859B2 (es) |
| EP (2) | EP1516626B1 (es) |
| JP (1) | JP2007505841A (es) |
| CN (1) | CN1871023B (es) |
| AT (1) | ATE349224T1 (es) |
| AU (1) | AU2004271688B2 (es) |
| CA (1) | CA2538842C (es) |
| DE (1) | DE60310717T2 (es) |
| DK (1) | DK1516626T3 (es) |
| ES (2) | ES2278101T3 (es) |
| NO (1) | NO20061368L (es) |
| PT (1) | PT1516626E (es) |
| SI (1) | SI1516626T1 (es) |
| WO (1) | WO2005025599A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1516626T3 (da) * | 2003-09-17 | 2007-04-30 | Alpharma Aps | Teicoplanin-sammensætning med forbedret antibiotisk aktivitet |
| EP1806150A1 (en) * | 2006-01-05 | 2007-07-11 | NEED PHARMA S.r.l. | Teicoplanin composition |
| US20070173438A1 (en) * | 2006-01-13 | 2007-07-26 | The Scripps Research Institute | [PSI[CH2NH]PG4] glycopeptide antibiotic analogs |
| KR20100109934A (ko) | 2007-12-26 | 2010-10-11 | 시오노기세야쿠 가부시키가이샤 | 글리코펩티드 항생 물질 배당화 유도체 |
| CN106132980A (zh) * | 2014-01-28 | 2016-11-16 | 中央研究院 | 肽可霉素类似物及其用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1496386A (en) * | 1975-03-05 | 1977-12-30 | Lepetit Spa | Antibiotics |
| GB8307847D0 (en) * | 1983-03-22 | 1983-04-27 | Lepetit Spa | Antibiotics l 17054 and l 17046 |
| GB8420405D0 (en) * | 1984-08-10 | 1984-09-12 | Lepetit Spa | Preparing antibiotic l 17046 |
| GB8512795D0 (en) * | 1985-05-21 | 1985-06-26 | Lepetit Spa | Increasing ratio of components of teicoplanin a2 complex |
| GB8608798D0 (en) | 1986-04-11 | 1986-05-14 | Lepetit Spa | Recovery of glycopeptide antibiotics from aqueous solutions |
| GB8726859D0 (en) * | 1987-11-17 | 1987-12-23 | Lepetit Spa | 22-dechlorotei-coplanins |
| IE64155B1 (en) * | 1989-03-29 | 1995-07-12 | Lepetit Spa | New substituted alkylamide derivatives of teicoplanin |
| JPH0597672A (ja) * | 1991-10-08 | 1993-04-20 | Terumo Corp | アミド誘導体含有固形製剤およびその製造方法 |
| DK1516626T3 (da) | 2003-09-17 | 2007-04-30 | Alpharma Aps | Teicoplanin-sammensætning med forbedret antibiotisk aktivitet |
-
2003
- 2003-09-17 DK DK03021000T patent/DK1516626T3/da active
- 2003-09-17 ES ES03021000T patent/ES2278101T3/es not_active Expired - Lifetime
- 2003-09-17 SI SI200330642T patent/SI1516626T1/sl unknown
- 2003-09-17 DE DE60310717T patent/DE60310717T2/de not_active Expired - Lifetime
- 2003-09-17 EP EP03021000A patent/EP1516626B1/en not_active Expired - Lifetime
- 2003-09-17 AT AT03021000T patent/ATE349224T1/de active
- 2003-09-17 PT PT03021000T patent/PT1516626E/pt unknown
-
2004
- 2004-09-17 ES ES04762852T patent/ES2421598T3/es not_active Expired - Lifetime
- 2004-09-17 US US10/944,601 patent/US7981859B2/en active Active
- 2004-09-17 CN CN2004800300227A patent/CN1871023B/zh not_active Expired - Fee Related
- 2004-09-17 US US10/572,160 patent/US7919470B2/en active Active
- 2004-09-17 WO PCT/DK2004/000632 patent/WO2005025599A1/en not_active Ceased
- 2004-09-17 JP JP2006526522A patent/JP2007505841A/ja active Pending
- 2004-09-17 EP EP04762852.4A patent/EP1670496B1/en not_active Expired - Lifetime
- 2004-09-17 CA CA2538842A patent/CA2538842C/en not_active Expired - Fee Related
- 2004-09-17 AU AU2004271688A patent/AU2004271688B2/en not_active Ceased
-
2006
- 2006-03-24 NO NO20061368A patent/NO20061368L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PT1516626E (pt) | 2007-04-30 |
| US20070287663A1 (en) | 2007-12-13 |
| CA2538842A1 (en) | 2005-03-24 |
| US20050080004A1 (en) | 2005-04-14 |
| EP1670496B1 (en) | 2013-05-22 |
| CN1871023A (zh) | 2006-11-29 |
| DE60310717T2 (de) | 2007-10-11 |
| SI1516626T1 (sl) | 2007-04-30 |
| AU2004271688A1 (en) | 2005-03-24 |
| DK1516626T3 (da) | 2007-04-30 |
| EP1516626B1 (en) | 2006-12-27 |
| EP1670496A1 (en) | 2006-06-21 |
| CN1871023B (zh) | 2012-08-22 |
| JP2007505841A (ja) | 2007-03-15 |
| US7919470B2 (en) | 2011-04-05 |
| ATE349224T1 (de) | 2007-01-15 |
| CA2538842C (en) | 2012-08-21 |
| EP1516626A1 (en) | 2005-03-23 |
| US7981859B2 (en) | 2011-07-19 |
| AU2004271688B2 (en) | 2009-05-28 |
| DE60310717D1 (de) | 2007-02-08 |
| ES2278101T3 (es) | 2007-08-01 |
| WO2005025599A1 (en) | 2005-03-24 |
| NO20061368L (no) | 2006-06-15 |
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