UA91848C2 - Применение соединений диосметина в лечении и предотвращении тромботическим патологиям - Google Patents

Применение соединений диосметина в лечении и предотвращении тромботическим патологиям

Info

Publication number
UA91848C2
UA91848C2 UAA200710762A UAA200710762A UA91848C2 UA 91848 C2 UA91848 C2 UA 91848C2 UA A200710762 A UAA200710762 A UA A200710762A UA A200710762 A UAA200710762 A UA A200710762A UA 91848 C2 UA91848 C2 UA 91848C2
Authority
UA
Ukraine
Prior art keywords
prevention
treatment
thrombotic
diosmetin
pathologies
Prior art date
Application number
UAA200710762A
Other languages
English (en)
Ukrainian (uk)
Inventor
Тоне Верберен
Ален Рюпен
Патрисия Сансильвестри-Морель
Мари-Одиль Валле
Мари-Франсуаз Буссар
Мишель Виерзбики
Original Assignee
Ле Лаборатуар Сервье
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ле Лаборатуар Сервье filed Critical Ле Лаборатуар Сервье
Publication of UA91848C2 publication Critical patent/UA91848C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/32—2,3-Dihydro derivatives, e.g. flavanones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Применение соединений диосметина в получении фармацевтических композиций, предназначенных для предотвращения и/или лечения тромботических патологий и патологий с риском тромбоза.
UAA200710762A 2005-03-01 2006-02-28 Применение соединений диосметина в лечении и предотвращении тромботическим патологиям UA91848C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0502044A FR2882654B1 (fr) 2005-03-01 2005-03-01 Utilisation de derives de la diosmetine pour le traitement et la prevention des pathologies thrombotiques

Publications (1)

Publication Number Publication Date
UA91848C2 true UA91848C2 (ru) 2010-09-10

Family

ID=35134198

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200710762A UA91848C2 (ru) 2005-03-01 2006-02-28 Применение соединений диосметина в лечении и предотвращении тромботическим патологиям

Country Status (18)

Country Link
US (1) US20080176934A1 (ru)
EP (1) EP1853253A1 (ru)
JP (1) JP2008531660A (ru)
KR (2) KR20090128581A (ru)
CN (1) CN101132788A (ru)
AR (1) AR053149A1 (ru)
AU (1) AU2006219853B2 (ru)
BR (1) BRPI0607562A2 (ru)
CA (1) CA2599658A1 (ru)
EA (1) EA013078B1 (ru)
FR (1) FR2882654B1 (ru)
MA (1) MA29316B1 (ru)
MX (1) MX2007010364A (ru)
NO (1) NO20074941L (ru)
NZ (1) NZ560749A (ru)
UA (1) UA91848C2 (ru)
WO (1) WO2006092490A1 (ru)
ZA (1) ZA200707472B (ru)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2002835A1 (en) 2007-06-04 2008-12-17 GenKyo Tex Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
FR2929276B1 (fr) * 2008-04-01 2010-04-23 Servier Lab Nouveaux derives de diosmetine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
KR101162816B1 (ko) * 2008-04-01 2012-07-09 르 라보레또레 쎄르비에르 디오스메틴 화합물，이의 제조 방법 및 이를 함유하는 약제학적 조성물
EP2166010A1 (en) 2008-09-23 2010-03-24 Genkyo Tex Sa Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
EP2166009A1 (en) 2008-09-23 2010-03-24 Genkyo Tex Sa Pyrazolo pyridine derivatives as nadph oxidase inhibitors
EP2165707A1 (en) 2008-09-23 2010-03-24 Genkyo Tex Sa Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
WO2010062681A2 (en) * 2008-10-30 2010-06-03 University Of South Florida Luteolin and diosmin/diosmetin as novel stat3 inhibitors for treating autism
EP2305679A1 (en) 2009-09-28 2011-04-06 GenKyoTex SA Pyrazoline dione derivatives as nadph oxidase inhibitors
KR102274211B1 (ko) 2011-11-23 2021-07-09 인3바이오 리미티드 재조합 단백질 및 그들의 치료적 용도
EP3034500A1 (en) 2014-12-17 2016-06-22 Genkyotex Sa Amido thiazole derivatives as NADPH oxidase inhibitors
JP2019507796A (ja) * 2016-03-11 2019-03-22 エイチ リー モフィット キャンサー センター アンド リサーチ インスティテュート インコーポレイテッド イカリイン及びイカリチン誘導体
WO2018107688A1 (zh) 2016-12-15 2018-06-21 深圳瑞健生命科学研究院有限公司 一种预防和治疗脂肪肝的方法
TWI746581B (zh) * 2016-12-15 2021-11-21 大陸商深圳瑞健生命科學硏究院有限公司 纖溶酶原在製備預防和治療脂質腎損傷之藥劑上的用途
WO2018107707A1 (zh) * 2016-12-15 2018-06-21 深圳瑞健生命科学研究院有限公司 一种改善心脏病变的方法
US11207387B2 (en) 2016-12-15 2021-12-28 Talengen International Limited Method and drug for preventing and treating obesity
CN108210915A (zh) * 2016-12-15 2018-06-29 深圳瑞健生命科学研究院有限公司 改善心脏病变的药物及其用途
CN106822087A (zh) * 2017-01-12 2017-06-13 西南大学 香叶木素在制备治疗ⅱ型糖尿病的药物中的应用
CN109280067B (zh) * 2017-07-21 2022-07-05 南京正大天晴制药有限公司 香叶木苷衍生物、其制备方法以及医药用途
EP3479843A1 (en) 2017-11-01 2019-05-08 GenKyoTex Suisse SA Use of nox inhibitors for treatment of cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2701261B1 (fr) * 1993-02-05 1995-03-31 Adir Nouveaux composés glucuronides de la diosmétine, leur procédé de préparation et les compositions pharmaceutiques les renfermant.
FR2726273B1 (fr) * 1994-10-26 1996-12-06 Adir Nouveaux derives de la diosmetine, leur procede de preparation et les compositions pharmaceutiques les contenant
FR2748025B1 (fr) * 1996-04-25 1998-10-30 Adir Nouveaux acides et esters de la diosmetine, et les compositions pharmaceutiques les contenant
DE59909616D1 (de) * 1998-10-30 2004-07-01 Merck Patent Gmbh Verfahren zur herstellung von luteolin und luteolin-derivaten

Also Published As

Publication number Publication date
JP2008531660A (ja) 2008-08-14
CA2599658A1 (fr) 2006-09-08
MA29316B1 (fr) 2008-03-03
MX2007010364A (es) 2007-09-25
BRPI0607562A2 (pt) 2009-09-15
NO20074941L (no) 2007-10-01
WO2006092490A1 (fr) 2006-09-08
AU2006219853B2 (en) 2011-06-09
KR20090128581A (ko) 2009-12-15
KR100971589B1 (ko) 2010-07-20
KR20070110395A (ko) 2007-11-16
FR2882654A1 (fr) 2006-09-08
EP1853253A1 (fr) 2007-11-14
US20080176934A1 (en) 2008-07-24
AR053149A1 (es) 2007-04-25
EA200701820A1 (ru) 2008-02-28
ZA200707472B (en) 2008-11-26
AU2006219853A1 (en) 2006-09-08
CN101132788A (zh) 2008-02-27
NZ560749A (en) 2010-11-26
FR2882654B1 (fr) 2007-04-27
EA013078B1 (ru) 2010-02-26

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