UA91848C2 - Применение соединений диосметина в лечении и предотвращении тромботическим патологиям - Google Patents

Применение соединений диосметина в лечении и предотвращении тромботическим патологиям

Info

Publication number
UA91848C2
UA91848C2 UAA200710762A UAA200710762A UA91848C2 UA 91848 C2 UA91848 C2 UA 91848C2 UA A200710762 A UAA200710762 A UA A200710762A UA A200710762 A UAA200710762 A UA A200710762A UA 91848 C2 UA91848 C2 UA 91848C2
Authority
UA
Ukraine
Prior art keywords
prevention
treatment
thrombotic
diosmetin
pathologies
Prior art date
Application number
UAA200710762A
Other languages
English (en)
Ukrainian (uk)
Inventor
Тоне Верберен
Ален Рюпен
Патрисия Сансильвестри-Морель
Мари-Одиль Валле
Мари-Франсуаз Буссар
Мишель Виерзбики
Original Assignee
Ле Лаборатуар Сервье
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ле Лаборатуар Сервье filed Critical Ле Лаборатуар Сервье
Publication of UA91848C2 publication Critical patent/UA91848C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/32—2,3-Dihydro derivatives, e.g. flavanones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Применение соединений диосметина в получении фармацевтических композиций, предназначенных для предотвращения и/или лечения тромботических патологий и патологий с риском тромбоза.
UAA200710762A 2005-03-01 2006-02-28 Применение соединений диосметина в лечении и предотвращении тромботическим патологиям UA91848C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0502044A FR2882654B1 (fr) 2005-03-01 2005-03-01 Utilisation de derives de la diosmetine pour le traitement et la prevention des pathologies thrombotiques

Publications (1)

Publication Number Publication Date
UA91848C2 true UA91848C2 (ru) 2010-09-10

Family

ID=35134198

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200710762A UA91848C2 (ru) 2005-03-01 2006-02-28 Применение соединений диосметина в лечении и предотвращении тромботическим патологиям

Country Status (18)

Country Link
US (1) US20080176934A1 (ru)
EP (1) EP1853253A1 (ru)
JP (1) JP2008531660A (ru)
KR (2) KR20090128581A (ru)
CN (1) CN101132788A (ru)
AR (1) AR053149A1 (ru)
AU (1) AU2006219853B2 (ru)
BR (1) BRPI0607562A2 (ru)
CA (1) CA2599658A1 (ru)
EA (1) EA013078B1 (ru)
FR (1) FR2882654B1 (ru)
MA (1) MA29316B1 (ru)
MX (1) MX2007010364A (ru)
NO (1) NO20074941L (ru)
NZ (1) NZ560749A (ru)
UA (1) UA91848C2 (ru)
WO (1) WO2006092490A1 (ru)
ZA (1) ZA200707472B (ru)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2002835A1 (en) 2007-06-04 2008-12-17 GenKyo Tex Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
FR2929276B1 (fr) * 2008-04-01 2010-04-23 Servier Lab Nouveaux derives de diosmetine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
KR101162816B1 (ko) * 2008-04-01 2012-07-09 르 라보레또레 쎄르비에르 디오스메틴 화합물，이의 제조 방법 및 이를 함유하는 약제학적 조성물
EP2166009A1 (en) 2008-09-23 2010-03-24 Genkyo Tex Sa Pyrazolo pyridine derivatives as nadph oxidase inhibitors
EP2165707A1 (en) 2008-09-23 2010-03-24 Genkyo Tex Sa Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
EP2166010A1 (en) 2008-09-23 2010-03-24 Genkyo Tex Sa Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
WO2010062681A2 (en) * 2008-10-30 2010-06-03 University Of South Florida Luteolin and diosmin/diosmetin as novel stat3 inhibitors for treating autism
EP2305679A1 (en) 2009-09-28 2011-04-06 GenKyoTex SA Pyrazoline dione derivatives as nadph oxidase inhibitors
BR112014012460B1 (pt) 2011-11-23 2021-01-12 Bioven 3 Limited proteínas recombinantes
EP3034500A1 (en) 2014-12-17 2016-06-22 Genkyotex Sa Amido thiazole derivatives as NADPH oxidase inhibitors
EP3426242A4 (en) * 2016-03-11 2020-03-18 H. Lee Moffitt Cancer Center And Research Institute, Inc. ICARIIN AND ICARITIN DERIVATIVES
TW201822805A (zh) 2016-12-15 2018-07-01 深圳瑞健生命科學硏究院有限公司 一種預防和治療脂肪異常沉積導致的組織損傷的方法
TW201829448A (zh) 2016-12-15 2018-08-16 大陸商深圳瑞健生命科學硏究院有限公司 纖溶酶原在製備預防或治療肥胖症及疾病倂發的肥胖的藥物中的用途
EP3556385A4 (en) * 2016-12-15 2020-12-30 Talengen International Limited PROCESS FOR ALLEGING HEART DISEASE
CN108210915A (zh) * 2016-12-15 2018-06-29 深圳瑞健生命科学研究院有限公司 改善心脏病变的药物及其用途
WO2018107689A1 (zh) * 2016-12-15 2018-06-21 深圳瑞健生命科学研究院有限公司 一种预防和治疗脂质肾损伤的方法
CN106822087A (zh) * 2017-01-12 2017-06-13 西南大学 香叶木素在制备治疗ⅱ型糖尿病的药物中的应用
CN109280067B (zh) * 2017-07-21 2022-07-05 南京正大天晴制药有限公司 香叶木苷衍生物、其制备方法以及医药用途
EP3479843A1 (en) 2017-11-01 2019-05-08 GenKyoTex Suisse SA Use of nox inhibitors for treatment of cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2701261B1 (fr) * 1993-02-05 1995-03-31 Adir Nouveaux composés glucuronides de la diosmétine, leur procédé de préparation et les compositions pharmaceutiques les renfermant.
FR2726273B1 (fr) * 1994-10-26 1996-12-06 Adir Nouveaux derives de la diosmetine, leur procede de preparation et les compositions pharmaceutiques les contenant
FR2748025B1 (fr) * 1996-04-25 1998-10-30 Adir Nouveaux acides et esters de la diosmetine, et les compositions pharmaceutiques les contenant
CA2348392A1 (en) * 1998-10-30 2000-05-11 Merck Patent Gesellschaft Mit Beschraenkter Haftung Method for producing luteolin and luteolin derivatives

Also Published As

Publication number Publication date
AU2006219853A1 (en) 2006-09-08
EP1853253A1 (fr) 2007-11-14
FR2882654A1 (fr) 2006-09-08
BRPI0607562A2 (pt) 2009-09-15
FR2882654B1 (fr) 2007-04-27
KR20090128581A (ko) 2009-12-15
CN101132788A (zh) 2008-02-27
MX2007010364A (es) 2007-09-25
WO2006092490A1 (fr) 2006-09-08
KR100971589B1 (ko) 2010-07-20
AU2006219853B2 (en) 2011-06-09
NO20074941L (no) 2007-10-01
MA29316B1 (fr) 2008-03-03
KR20070110395A (ko) 2007-11-16
NZ560749A (en) 2010-11-26
EA013078B1 (ru) 2010-02-26
AR053149A1 (es) 2007-04-25
JP2008531660A (ja) 2008-08-14
US20080176934A1 (en) 2008-07-24
EA200701820A1 (ru) 2008-02-28
ZA200707472B (en) 2008-11-26
CA2599658A1 (fr) 2006-09-08

Similar Documents

Publication Publication Date Title
MX2009006704A (es) Derivados de amina triciclicos como inhibidores de proteina de tirosina cinasa.
MX2009000285A (es) Piperidinas sustituidas que incrementan la actividad de p53 y usos de las mismas.
IL188050A (en) The history of azaindazole, their medicinal preparations and their uses
TW200728285A (en) Diacylindazole derivatives as inhibitors of lipases and phospholipases
IL233634A0 (en) Methods, compositions and kits for treating medical conditions
CL2007002261A1 (es) Compuestos derivados de imidazo[1,2-b]piridazina, inhibidores de quinasa; composicion farmaceutica; y uso en el tratamiento o prevencion del cancer.
EA201300242A1 (ru) Фармацевтические композиции, содержащие замещенные ациланилиды
TW200745124A (en) Azepinoindole derivatives as pharmaceutical agents
BRPI0720124A2 (pt) Composições farmacêuticas e seus métodos de uso.
TNSN08178A1 (en) Triazolopyridine derivatives as inhibitors of lipases and phospholipases
NO20074941L (no) Anvendelse av diosmetinforbindelser i behandlingen og forebyggingen av trombotiske patologier
TW200800967A (en) Benzimidazole thiophene compounds
NO20075111L (no) Farmasoytisk sammensetning
TNSN08400A1 (en) Organic compounds and their uses
MX2010006206A (es) Derivados de oxindol substituidos por 5-halogeno y el uso de los mismos para el tratamiento de enfermedades dependientes de la vasopresina.
CL2007003038A1 (es) Compuestos derivados de 2-fenil-6-aminocarbonil-pirimidina; composicion farmaceutica; y uso en el tratamiento de trastornos vasculares oclusivos.
MX2008015775A (es) Compuestos y composiciones para tratamiento de cancer.
BRPI0720323A2 (pt) composto, método de tratamento, composição farmacêutica e uso do composto
CY1111762T1 (el) Διενυδρη παμοϊκη ολανζαπiνη
TW200716091A (en) New therapeutic combinations for the treatment or prevention of psychotic disorders
CL2008003602A1 (es) Compuestos derivados de triazolotriazinas y triazolopirazinas sustituidas; composicion farmaceutica; y su uso en el tratamiento y/o profilaxis de trastornos hematologicos.
SE0300457D0 (sv) Novel compounds
EP2124554A4 (en) COMPOSITIONS AND METHODS FOR CANCER TREATMENT
NO20091386L (no) Fenyloksyanilinderivater
CY1110787T1 (el) Νεα μορφινικα παραγωγα