ES2421915T3 - Derivados de amida del ácido hialurónico en osteoartrosis - Google Patents
Derivados de amida del ácido hialurónico en osteoartrosisInfo
- Publication number
- ES2421915T3 ES2421915T3 ES06707203T ES06707203T ES2421915T3 ES 2421915 T3 ES2421915 T3 ES 2421915T3 ES 06707203 T ES06707203 T ES 06707203T ES 06707203 T ES06707203 T ES 06707203T ES 2421915 T3 ES2421915 T3 ES 2421915T3
- Authority
- ES
- Spain
- Prior art keywords
- hyaluronic acid
- osteoarthritis
- acid amide
- amide derivatives
- hexadecylamides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
Abstract
Hexadecilamidas de ácido hialurónico caracterizadas porque la hexadecilamida del ácido hialurónico tiene ungrado de amidación entre 0.1 y 5% para usar en el tratamiento de articulaciones afectadas por osteoartrosis,trauma, inflamación y/o desgaste debido al envejecimiento de la estructura de la articulación.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000056A ITPD20050056A1 (it) | 2005-03-02 | 2005-03-02 | Derivati ammidici del'acido ialuronico in osteoartrosi |
| PCT/EP2006/001644 WO2006092233A1 (en) | 2005-03-02 | 2006-02-20 | Amide derivatives of hyaluronic acid in osteoarthrosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2421915T3 true ES2421915T3 (es) | 2013-09-06 |
Family
ID=36582056
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES06707203T Expired - Lifetime ES2421915T3 (es) | 2005-03-02 | 2006-02-20 | Derivados de amida del ácido hialurónico en osteoartrosis |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7863256B2 (es) |
| EP (2) | EP1853279B1 (es) |
| JP (1) | JP5047814B2 (es) |
| AU (1) | AU2006220034B2 (es) |
| CA (1) | CA2598331C (es) |
| CY (1) | CY1115215T1 (es) |
| DK (1) | DK1853279T3 (es) |
| ES (1) | ES2421915T3 (es) |
| IL (1) | IL185248A0 (es) |
| IT (1) | ITPD20050056A1 (es) |
| PL (1) | PL1853279T3 (es) |
| PT (1) | PT1853279E (es) |
| SI (1) | SI1853279T1 (es) |
| WO (1) | WO2006092233A1 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2360188B1 (en) * | 2008-11-05 | 2014-09-17 | National University Corporation Tokyo Medical and Dental University | Hyaluronic acid derivative and pharmaceutical composition thereof |
| RU2409664C1 (ru) * | 2009-04-29 | 2011-01-20 | Государственное образовательное учреждение высшего профессионального образования "Оренбургский государственный университет" | Способ получения жизнеспособных клеток молочной железы |
| IT1394570B1 (it) * | 2009-07-02 | 2012-07-05 | Fidia Farmaceutici | Materiale biologico adatto per la terapia dell osteoartrosi del danno dei legamenti e per il trattamento delle patologie delle articolazioni. |
| IT1395392B1 (it) | 2009-08-27 | 2012-09-14 | Fidia Farmaceutici | Geli viscoelastici come nuovi filler |
| ITPD20120098A1 (it) * | 2012-03-30 | 2013-10-01 | Fidia Farmaceutici | "nuove formulazioni faramaceutiche contenenti condroitin solfato e derivati dell'acido ialuronico" |
| ITPD20120173A1 (it) * | 2012-05-31 | 2013-12-01 | Fidia Farmaceutici | "nuovo sistema di rilascio di proteine idrofobiche" |
| PL2900247T3 (pl) * | 2012-09-26 | 2018-05-30 | Bone Therapeutics S.A. | Kompozycje zawierające osocze poddane obróbce rozpuszczalnikiem/detergentem i kwas hialuronowy do zastosowania w leczeniu zaburzeń układu mięśniowo-szkieletowego |
| EP4137139A1 (en) | 2013-07-10 | 2023-02-22 | Matrix Biology Institute | Compositions of hyaluronan with high elasticity and uses thereof |
| ES2871199T3 (es) | 2015-09-24 | 2021-10-28 | Matrix Biology Inst | Composiciones de hialuronano de alta elasticidad y métodos de uso de las mismas |
| RU2621269C1 (ru) * | 2016-04-27 | 2017-06-01 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Чеченский государственный университет" | Способ деалгезии при гонартрозе |
| IT201700110784A1 (it) * | 2017-10-03 | 2019-04-03 | Fidia Farm Spa | Composizioni farmaceutiche contenenti Acido Ialuronico e Carnosina e relativo uso |
| IT201900006038A1 (it) | 2019-04-18 | 2020-10-18 | Fidia Farm Spa | Composizioni farmaceutiche comprendenti statine e derivati dell’acido ialuronico |
| IT201900009933A1 (it) * | 2019-06-24 | 2020-12-24 | Fidia Farm Spa | Composizioni farmaceutiche comprendenti derivati ammidici dell'acido ialuronico per uso nel trattamento di traumi ossei, in particolare in pazienti con problemi di osteopenia o osteoporosi |
| IT202000005692A1 (it) | 2020-03-17 | 2021-09-17 | Fidia Farm Spa | Bio-inchiostro per stampa 3D, relativo coniugato e processo di preparazione di un intermedio costituito da un linker fotoreattivo |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55161801A (en) | 1979-06-06 | 1980-12-16 | Seikagaku Kogyo Co Ltd | Fluorescence-labeled acid mucopolysaccharide and preparation thereof |
| IN163192B (es) | 1983-10-11 | 1988-08-20 | Fidia Spa | |
| US4713448A (en) | 1985-03-12 | 1987-12-15 | Biomatrix, Inc. | Chemically modified hyaluronic acid preparation and method of recovery thereof from animal tissues |
| US4851521A (en) | 1985-07-08 | 1989-07-25 | Fidia, S.P.A. | Esters of hyaluronic acid |
| US4937270A (en) | 1987-09-18 | 1990-06-26 | Genzyme Corporation | Water insoluble derivatives of hyaluronic acid |
| US6174999B1 (en) | 1987-09-18 | 2001-01-16 | Genzyme Corporation | Water insoluble derivatives of polyanionic polysaccharides |
| IT1217458B (it) | 1988-05-02 | 1990-03-22 | Crinos Ind Farmacoriologica S | Sulfoamino derivati di condroitin solfati,del dermatan solfato e dell' acido ialuronico e loro proprieta' farmacologiche |
| US5510418A (en) | 1988-11-21 | 1996-04-23 | Collagen Corporation | Glycosaminoglycan-synthetic polymer conjugates |
| JPH0755961B2 (ja) | 1989-04-18 | 1995-06-14 | 工業技術院長 | 新規なヒアルロン酸誘導体及びその製造方法 |
| EP0416250A3 (en) | 1989-08-01 | 1991-08-28 | The Research Foundation Of State University Of New York | N-acylurea and o-acylisourea derivatives of hyaluronic acid |
| US5733891A (en) * | 1990-10-18 | 1998-03-31 | Shiseido Co., Ltd. | Compound for medicinal ingredient and hyaluronic acid and process for producing the same |
| CA2070672C (en) | 1990-10-18 | 2002-10-08 | Kazuo Akima | Compound of medicinal ingredient and hyaluronic acid and process for producing the same |
| JP2855307B2 (ja) | 1992-02-05 | 1999-02-10 | 生化学工業株式会社 | 光反応性グリコサミノグリカン、架橋グリコサミノグリカン及びそれらの製造方法 |
| US5612360A (en) | 1992-06-03 | 1997-03-18 | Eli Lilly And Company | Angiotensin II antagonists |
| IT1260154B (it) * | 1992-07-03 | 1996-03-28 | Lanfranco Callegaro | Acido ialuronico e suoi derivati in polimeri interpenetranti (ipn) |
| JP3209457B2 (ja) | 1992-12-11 | 2001-09-17 | 本田技研工業株式会社 | バッテリの残容量検出方法 |
| IT1263316B (it) * | 1993-02-12 | 1996-08-05 | Fidia Advanced Biopolymers Srl | Tessuto non tessuto multistrato in cui uno degli strati e' costituito essenzialmente da esteri dell'acido ialuronico |
| IT1268955B1 (it) | 1994-03-11 | 1997-03-18 | Fidia Advanced Biopolymers Srl | Esteri attivi di polisaccaridi carbossilici |
| CA2162957C (en) | 1994-11-17 | 2011-08-02 | Michinori Waki | Cinnamic acid derivative |
| IT1281876B1 (it) | 1995-05-10 | 1998-03-03 | Fidia Advanced Biopolymers Srl | Acido ialuronico e suoi derivati esterei per la preparazione di matrici per il rilascio controllato di farmaci. |
| JP4018181B2 (ja) | 1995-11-07 | 2007-12-05 | 生化学工業株式会社 | グリコサミノグリカン誘導体およびその製造法 |
| JP3925955B2 (ja) | 1996-04-26 | 2007-06-06 | 株式会社クラレ | 癒着防止材 |
| US5657582A (en) * | 1996-06-21 | 1997-08-19 | Chitwood; Mark L. | Rain gutter downspout noise attenuation apparatus |
| JP3955652B2 (ja) | 1996-10-15 | 2007-08-08 | 株式会社ネーテック | 合成アミノ糖類誘導体及びその製造方法 |
| JPH10298164A (ja) | 1997-02-27 | 1998-11-10 | Tanabe Seiyaku Co Ltd | イソキノリノン誘導体、その製法及びその合成中間体 |
| ATE229038T1 (de) * | 1997-04-04 | 2002-12-15 | Fidia Advanced Biopolymers Srl | N-sulfatierte hyaluronsäureverbindungen, ihre derivate und verfahren zu ihrer herstellung |
| JP3410476B2 (ja) | 1997-04-18 | 2003-05-26 | 大鵬薬品工業株式会社 | 新規なエポキシコハク酸アミド誘導体又はその塩 |
| GB9710990D0 (en) | 1997-05-28 | 1997-07-23 | Danisco | Modification process |
| ITPD980169A1 (it) | 1998-07-06 | 2000-01-06 | Fidia Advanced Biopolymers Srl | Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione. |
| IT1303735B1 (it) | 1998-11-11 | 2001-02-23 | Falorni Italia Farmaceutici S | Acidi ialuronici reticolati e loro usi medici. |
| KR100375299B1 (ko) | 2000-10-10 | 2003-03-10 | 주식회사 엘지생명과학 | 히알루론산의 가교결합형 아마이드 유도체와 이의 제조방법 |
| KR20040009891A (ko) | 2002-07-26 | 2004-01-31 | 주식회사 엘지생명과학 | 히알루론산의 유도체 겔 및 그 제조방법 |
-
2005
- 2005-03-02 IT IT000056A patent/ITPD20050056A1/it unknown
-
2006
- 2006-02-20 US US11/884,420 patent/US7863256B2/en active Active
- 2006-02-20 JP JP2007557379A patent/JP5047814B2/ja not_active Expired - Lifetime
- 2006-02-20 AU AU2006220034A patent/AU2006220034B2/en not_active Expired
- 2006-02-20 SI SI200631614T patent/SI1853279T1/sl unknown
- 2006-02-20 PT PT67072033T patent/PT1853279E/pt unknown
- 2006-02-20 DK DK06707203.3T patent/DK1853279T3/da active
- 2006-02-20 PL PL06707203T patent/PL1853279T3/pl unknown
- 2006-02-20 EP EP06707203.3A patent/EP1853279B1/en not_active Expired - Lifetime
- 2006-02-20 EP EP12156643A patent/EP2457574A1/en not_active Withdrawn
- 2006-02-20 CA CA2598331A patent/CA2598331C/en not_active Expired - Lifetime
- 2006-02-20 WO PCT/EP2006/001644 patent/WO2006092233A1/en not_active Ceased
- 2006-02-20 ES ES06707203T patent/ES2421915T3/es not_active Expired - Lifetime
-
2007
- 2007-08-13 IL IL185248A patent/IL185248A0/en active IP Right Grant
-
2013
- 2013-07-05 CY CY20131100568T patent/CY1115215T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI1853279T1 (sl) | 2013-08-30 |
| JP2008531148A (ja) | 2008-08-14 |
| US20080069884A1 (en) | 2008-03-20 |
| JP5047814B2 (ja) | 2012-10-10 |
| HK1106161A1 (en) | 2008-03-07 |
| CA2598331C (en) | 2013-07-30 |
| PT1853279E (pt) | 2013-07-18 |
| ITPD20050056A1 (it) | 2006-09-03 |
| US7863256B2 (en) | 2011-01-04 |
| IL185248A0 (en) | 2008-06-05 |
| CA2598331A1 (en) | 2006-09-08 |
| EP1853279B1 (en) | 2013-05-01 |
| AU2006220034A1 (en) | 2006-09-08 |
| WO2006092233A1 (en) | 2006-09-08 |
| EP1853279A1 (en) | 2007-11-14 |
| DK1853279T3 (da) | 2013-07-15 |
| CY1115215T1 (el) | 2017-01-04 |
| PL1853279T3 (pl) | 2013-09-30 |
| EP2457574A1 (en) | 2012-05-30 |
| AU2006220034B2 (en) | 2010-11-18 |
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