ES2478258T3 - Formulación farmacéutica que comprende compuestos de lantano - Google Patents
Formulación farmacéutica que comprende compuestos de lantano Download PDFInfo
- Publication number
- ES2478258T3 ES2478258T3 ES10151270.5T ES10151270T ES2478258T3 ES 2478258 T3 ES2478258 T3 ES 2478258T3 ES 10151270 T ES10151270 T ES 10151270T ES 2478258 T3 ES2478258 T3 ES 2478258T3
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutical formulation
- lanthanum carbonate
- lanthanum compounds
- lanthanum
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000002604 lanthanum compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229910017569 La2(CO3)3 Inorganic materials 0.000 abstract 3
- NZPIUJUFIFZSPW-UHFFFAOYSA-H lanthanum carbonate Chemical compound [La+3].[La+3].[O-]C([O-])=O.[O-]C([O-])=O.[O-]C([O-])=O NZPIUJUFIFZSPW-UHFFFAOYSA-H 0.000 abstract 3
- 229960001633 lanthanum carbonate Drugs 0.000 abstract 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 2
- 239000004615 ingredient Substances 0.000 abstract 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 239000007910 chewable tablet Substances 0.000 abstract 1
- 229940068682 chewable tablet Drugs 0.000 abstract 1
- 229940096516 dextrates Drugs 0.000 abstract 1
- 235000019359 magnesium stearate Nutrition 0.000 abstract 1
- 239000000377 silicon dioxide Substances 0.000 abstract 1
- 239000000454 talc Substances 0.000 abstract 1
- 229910052623 talc Inorganic materials 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/244—Lanthanides; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Una tableta masticable de carbonato de lantano, que comprende los siguientes ingredientes: Ingrediente % en peso Carbonato de lantano 26.5 Dextratos 69.3 Sílice anhidra coloidal 2.0 Talco Purificado 1.7 Estearato de magnesio 0.5 en donde el carbonato de lantano se hidrata con un contenido de agua con un valor promedio de 4 moles de agua.
Description
Claims (1)
-
imagen1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49756003P | 2003-08-26 | 2003-08-26 | |
| US497560P | 2003-08-26 | ||
| US51707803P | 2003-11-05 | 2003-11-05 | |
| US517078P | 2003-11-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2478258T3 true ES2478258T3 (es) | 2014-07-21 |
Family
ID=34221462
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09172030.0T Expired - Lifetime ES2532389T3 (es) | 2003-08-26 | 2004-08-26 | Formulación farmacéutica que comprende compuestos de lantano |
| ES04761727T Expired - Lifetime ES2343354T3 (es) | 2003-08-26 | 2004-08-26 | Formulacion farmaceutica que comprende compuestos de lantano. |
| ES10151270.5T Expired - Lifetime ES2478258T3 (es) | 2003-08-26 | 2004-08-26 | Formulación farmacéutica que comprende compuestos de lantano |
| ES14167982.9T Expired - Lifetime ES2592803T3 (es) | 2003-08-26 | 2004-08-26 | Formulación farmacéutica que comprende compuestos de lantano |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09172030.0T Expired - Lifetime ES2532389T3 (es) | 2003-08-26 | 2004-08-26 | Formulación farmacéutica que comprende compuestos de lantano |
| ES04761727T Expired - Lifetime ES2343354T3 (es) | 2003-08-26 | 2004-08-26 | Formulacion farmaceutica que comprende compuestos de lantano. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14167982.9T Expired - Lifetime ES2592803T3 (es) | 2003-08-26 | 2004-08-26 | Formulación farmacéutica que comprende compuestos de lantano |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US7465465B2 (es) |
| EP (4) | EP2133084B1 (es) |
| JP (2) | JP4896719B2 (es) |
| KR (1) | KR100830764B1 (es) |
| CN (1) | CN1871018B (es) |
| AT (2) | ATE460169T1 (es) |
| AU (2) | AU2004266050B2 (es) |
| BR (1) | BRPI0413394A8 (es) |
| CA (1) | CA2536959C (es) |
| CY (2) | CY1110241T1 (es) |
| CZ (1) | CZ17621U1 (es) |
| DE (2) | DE202004021169U1 (es) |
| DK (5) | DK2792363T3 (es) |
| EA (2) | EA012798B1 (es) |
| ES (4) | ES2532389T3 (es) |
| FI (1) | FI7568U1 (es) |
| HU (2) | HUE024906T2 (es) |
| IL (2) | IL173755A0 (es) |
| IS (1) | IS2893B (es) |
| MX (1) | MXPA06002257A (es) |
| NO (1) | NO342559B1 (es) |
| NZ (1) | NZ545633A (es) |
| PL (4) | PL2792363T3 (es) |
| PT (4) | PT2792363T (es) |
| SG (1) | SG145765A1 (es) |
| SI (4) | SI2133084T1 (es) |
| WO (1) | WO2005018651A1 (es) |
| ZA (1) | ZA200602213B (es) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9720061D0 (en) | 1997-09-19 | 1997-11-19 | Crosfield Joseph & Sons | Metal compounds as phosphate binders |
| GB0015745D0 (en) * | 2000-06-27 | 2000-08-16 | Shire Holdings Ag | Treatment of bone diseases |
| US7192609B2 (en) * | 2001-04-23 | 2007-03-20 | Shire International Licensing B.V. | Use of rare earth compounds for the prevention of kidney stone disease |
| US20060083791A1 (en) | 2002-05-24 | 2006-04-20 | Moerck Rudi E | Rare earth metal compounds methods of making, and methods of using the same |
| US20040161474A1 (en) * | 2002-05-24 | 2004-08-19 | Moerck Rudi E. | Rare earth metal compounds methods of making, and methods of using the same |
| MXPA06002257A (es) * | 2003-08-26 | 2006-05-17 | Shire Holdings Ag | Farmaceutica que comprende compuestos de lantano. |
| US7381428B2 (en) * | 2003-08-26 | 2008-06-03 | Shire International Licensing B.V. | Stabilized lanthanum carbonate compositions |
| JP4869229B2 (ja) * | 2004-07-27 | 2012-02-08 | シア ファーマシューティカルズ,インク. | 水酸化炭酸ランタンを用いた高リン血症を治療するための医薬組成物 |
| US7700608B2 (en) * | 2004-08-04 | 2010-04-20 | Shire Holdings Ag | Quinazoline derivatives and their use in the treatment of thrombocythemia |
| AU2005295609A1 (en) * | 2004-10-15 | 2006-04-27 | Spectrum Pharmaceuticals, Inc. | Phosphate binder with reduced pill burden |
| ITME20040015A1 (it) | 2004-12-07 | 2005-03-07 | Vincenzo Savica | Chewing gum, caramelle gommose, pastiglie, compresse a lento rilascio di chelanti fosfato e/o fosforo salivare e capsule a lento rilascio di chelanti fosfato e/o fosforo a livello gastroenterico. |
| EP1698233A1 (en) * | 2005-03-01 | 2006-09-06 | Bayer HealthCare AG | Reduction of digestibility of phosphorus in animal nutrition |
| JP2009504779A (ja) * | 2005-08-17 | 2009-02-05 | アルテアナノ インコーポレイテッド | 家畜における慢性腎不全及びその他の病気の治療:組成物及び方法 |
| JP2009504781A (ja) * | 2005-08-17 | 2009-02-05 | アルテアナノ インコーポレイテッド | 家畜における高リン血症:治療のための組成物、及び治療方法 |
| US20070104799A1 (en) * | 2005-11-09 | 2007-05-10 | Shire International Licensing B.V. | Treatment of chronic kidney disease (CKD) subjects using lanthanum compounds |
| MY157620A (en) | 2006-01-31 | 2016-06-30 | Cytochroma Dev Inc | A granular material of a solid water-soluble mixed metal compound capable of binding phosphate |
| CN100398112C (zh) * | 2006-03-24 | 2008-07-02 | 辽宁诺康生物制药有限责任公司 | 一种治疗血磷酸盐过多症的药物及其制备方法 |
| GB0714670D0 (en) | 2007-07-27 | 2007-09-05 | Ineos Healthcare Ltd | Use |
| JP5623275B2 (ja) * | 2007-07-31 | 2014-11-12 | カーギル インコーポレイテッド | 直接打錠可能なデキストロース |
| GB0720220D0 (en) | 2007-10-16 | 2007-11-28 | Ineos Healthcare Ltd | Compound |
| TWI468167B (zh) | 2007-11-16 | 2015-01-11 | 威佛(國際)股份有限公司 | 藥學組成物 |
| WO2009118760A2 (en) * | 2008-03-26 | 2009-10-01 | Matrix Laboratories Limited | Lanthanum composition |
| WO2010085520A1 (en) * | 2009-01-21 | 2010-07-29 | Mylan Inc. | Disintegrable formulations of lanthanum carbonate |
| WO2010106557A2 (en) * | 2009-03-20 | 2010-09-23 | Panacea Biotec Limited | Stable pharmaceutical formulations comprising anhydrous lanthanum carbonate and process for preparation thereof |
| GB0913525D0 (en) | 2009-08-03 | 2009-09-16 | Ineos Healthcare Ltd | Method |
| AU2010313075A1 (en) * | 2009-10-26 | 2012-05-31 | Alkem Laboratories Ltd. | Pharmaceutical compositions of lanthanum carbonate and process for the preparation thereof |
| GB201001779D0 (en) | 2010-02-04 | 2010-03-24 | Ineos Healthcare Ltd | Composition |
| KR101940207B1 (ko) * | 2010-05-12 | 2019-01-18 | 스펙트럼 파마슈티컬즈 인크 | 란탄 카보네이트 하이드록사이드, 란탄 옥시카보네이트 및 이들의 제조 및 사용 방법 |
| EP2441436A1 (de) | 2010-10-13 | 2012-04-18 | Fresenius Medical Care Deutschland GmbH | Phosphatbinderformulierung zur einfachen Einnahme |
| US8263119B2 (en) * | 2010-12-01 | 2012-09-11 | Shire Llc | Capsule formulations containing lanthanum compounds |
| US8697132B2 (en) | 2010-12-01 | 2014-04-15 | Shire Llc | Capsule and powder formulations containing lanthanum compounds |
| CN103127041A (zh) * | 2012-02-23 | 2013-06-05 | 南京卡文迪许生物工程技术有限公司 | 含有醋酸镧的药物组合物及其制备方法和用途 |
| DE102012209411A1 (de) * | 2012-06-04 | 2013-12-05 | Fim Biotech Gmbh | Mineralische Verbindung zur Reduzierung von anorganischen Phosphaten, insbesondere im Rahmen einer Nierenersatztherapie |
| CN104473963B (zh) * | 2014-12-24 | 2017-10-10 | 厦门科明达科技有限公司 | 稀土化学药碳酸镧咀嚼片的制备方法 |
| JP2016147827A (ja) * | 2015-02-12 | 2016-08-18 | 株式会社三和化学研究所 | 炭酸ランタン水和物を含有する医薬製剤 |
| US10058569B2 (en) | 2015-06-24 | 2018-08-28 | Lupin Limited | Lanthanum carbonate compositions |
| JP6093829B1 (ja) * | 2015-10-02 | 2017-03-08 | バイエル薬品株式会社 | ランタン化合物を含む医薬組成物 |
| JP6623753B2 (ja) * | 2015-12-28 | 2019-12-25 | ニプロ株式会社 | 炭酸ランタンを含む口腔内崩壊錠 |
| CN107213126B (zh) * | 2017-05-17 | 2020-06-23 | 西安棣加生物科技有限公司 | 一种3d打印技术制备治疗高磷血症的口腔速崩片的方法 |
| CN108969497A (zh) * | 2018-10-12 | 2018-12-11 | 沈阳华泰药物研究有限公司 | 一种碳酸镧片剂组合物及其制备方法 |
| EP4061340A4 (en) | 2019-11-21 | 2023-08-09 | Santa Farma Ilaç Sanayi A.S. | ORAL SOLID PHARMACEUTICAL COMPOSITIONS WITH LANTANHANE CARBONATE OCTAHYDRATE |
| CN113244179B (zh) * | 2021-05-21 | 2023-01-13 | 浙江仟源海力生制药有限公司 | 一种稳定性好的碳酸镧片剂及其制备方法和其应用 |
| US20230123099A1 (en) * | 2021-10-15 | 2023-04-20 | Fertin Pharma A/S | Dextrose tablets with improved mouthfeel |
| CN115813867B (zh) * | 2022-12-01 | 2024-05-24 | 山东齐都药业有限公司 | 碳酸镧冻干片及其制备方法 |
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2004
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