ES2533697T3 - Inhibidores peptídicos para mediar respuestas de estrés - Google Patents

Inhibidores peptídicos para mediar respuestas de estrés Download PDF

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Publication number
ES2533697T3
ES2533697T3 ES05774723.0T ES05774723T ES2533697T3 ES 2533697 T3 ES2533697 T3 ES 2533697T3 ES 05774723 T ES05774723 T ES 05774723T ES 2533697 T3 ES2533697 T3 ES 2533697T3
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Prior art keywords
peptide
peptide inhibitors
stress responses
antibody
mediate stress
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Expired - Lifetime
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ES05774723.0T
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English (en)
Inventor
Johannes Herkel
Irun R Cohen
Varda Rotter
Ansgar W Lohse
Neta Erez
Avishai Mimran
Na'aman Kam
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Yeda Research and Development Co Ltd
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Yeda Research and Development Co Ltd
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    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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Abstract

Un péptido que comprende un epítopo inmunorreactivo con un anticuerpo anti-idiotípico dirigido contra un anticuerpo anti-p53, en el que el anticuerpo anti-p53 es inmunorreactivo con al menos una parte del dominio regulador del extremo C-terminal de p53, y en el que el péptido muestra al menos una actividad seleccionada entre actividad anti-apoptótica y actividad antiinflamatoria, en el que el péptido tiene una secuencia de aminoácidos tal como se expone en una cualquiera de las SEC ID Nº: 1-8.

Description

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Claims (1)

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ES05774723.0T 2004-08-23 2005-08-23 Inhibidores peptídicos para mediar respuestas de estrés Expired - Lifetime ES2533697T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60325504P 2004-08-23 2004-08-23
US603255P 2004-08-23
PCT/IL2005/000908 WO2006021954A2 (en) 2004-08-23 2005-08-23 Peptide inhibitors for mediating stress responses

Publications (1)

Publication Number Publication Date
ES2533697T3 true ES2533697T3 (es) 2015-04-14

Family

ID=35967919

Family Applications (1)

Application Number Title Priority Date Filing Date
ES05774723.0T Expired - Lifetime ES2533697T3 (es) 2004-08-23 2005-08-23 Inhibidores peptídicos para mediar respuestas de estrés

Country Status (11)

Country Link
US (4) US8067008B2 (es)
EP (2) EP2578226B1 (es)
JP (1) JP4991544B2 (es)
CN (2) CN101035554A (es)
AU (1) AU2005276117C1 (es)
CA (1) CA2577196C (es)
DK (1) DK1781315T3 (es)
ES (1) ES2533697T3 (es)
HU (1) HUE024953T2 (es)
PL (1) PL1781315T3 (es)
WO (1) WO2006021954A2 (es)

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JP7350019B2 (ja) * 2018-05-31 2023-09-25 イミュニティ ファルマ リミテッド 筋萎縮性側索硬化症（ａｌｓ）を治療するための組成物、及び治療のためにそれを使用する方法
IL280101B2 (en) * 2018-07-11 2025-05-01 Immunity Pharma Ltd Peptide compounds and their therapeutic uses
IL272074B2 (en) * 2020-01-15 2024-12-01 Immunity Pharma Ltd Peptide compounds and methods of treating diseases using same

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BR112012002333A2 (pt) 2009-08-06 2017-07-18 Neuraltus Pharmaceuticals Inc método de reduzir os efeitos colaterais e método de potencializar o efeito de um imunomodulador administrado a um sujeito que dele necessita; métodos para tratar doença associada com excesso de ativação de monócitos para macrófagos ativados, diabetes tipo ii ou complicações relacionadas, doença associada com a migração de monócitos ou macrófagos ativados, doença associada a excesso de produção de scd14 e/ou scd163 por macrófagos ativados; composto de cloreto de sódio; composição farmacêutica; método para diagnosticar uma doença relacionada com macrófagos em um sujeito; e método para determinar a eficácia do tratamento com um agente oxidante para uma doença relacionada a macrófagos em um sujeito.
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CA2577196A1 (en) 2006-03-02
US20140329758A1 (en) 2014-11-06
CN103214555B (zh) 2015-05-13
AU2005276117B2 (en) 2012-04-12
US20150297693A1 (en) 2015-10-22
EP1781315B1 (en) 2015-01-07
JP2008510796A (ja) 2008-04-10
US20080267983A1 (en) 2008-10-30
EP2578226A1 (en) 2013-04-10
WO2006021954A3 (en) 2007-02-08
PL1781315T3 (pl) 2015-08-31
US20120171233A1 (en) 2012-07-05
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EP1781315A4 (en) 2009-07-22
CN103214555A (zh) 2013-07-24
JP4991544B2 (ja) 2012-08-01
HUE024953T2 (en) 2016-02-29
US8790653B2 (en) 2014-07-29
CN101035554A (zh) 2007-09-12
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AU2005276117C1 (en) 2013-04-18
CA2577196C (en) 2016-01-12

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