ES2552598T3 - Hemocianina y secuencia de ácido nucleico que codifica para la misma - Google Patents
Hemocianina y secuencia de ácido nucleico que codifica para la misma Download PDFInfo
- Publication number
- ES2552598T3 ES2552598T3 ES00918811.1T ES00918811T ES2552598T3 ES 2552598 T3 ES2552598 T3 ES 2552598T3 ES 00918811 T ES00918811 T ES 00918811T ES 2552598 T3 ES2552598 T3 ES 2552598T3
- Authority
- ES
- Spain
- Prior art keywords
- domain
- seq
- klh1
- hth1
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000007523 nucleic acids Chemical group 0.000 title abstract 7
- 108091028043 Nucleic acid sequence Proteins 0.000 title abstract 4
- 108060003552 hemocyanin Proteins 0.000 title abstract 3
- 101100123569 Megathura crenulata KLH1 gene Proteins 0.000 abstract 24
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0003—Invertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/855—Proteins from animals other than mammals or birds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Molécula de ácido nucleico, que comprende una secuencia de ácido nucleico que codifica para una hemocianina, un dominio de hemocianina o una variante según la reivindicación 1(c), seleccionándose la secuencia de ácido nucleico de: (a) secuencias de ácido nucleico, que se seleccionan del grupo de las secuencias de ADN indicadas a continuación o de las secuencias de ARN correspondientes a las mismas: SEQ ID NO:4 (dominio d de HtH1), SEQ ID NO:5 (dominio e de HtH1), SEQ ID NO:7 (dominio g de HtH1), SEQ ID NO: 8 (dominio h de HtH1), SEQ ID NO: 16 (dominio b de KLH1 parcial), SEQ ID NO : 17 (dominio c de KLH1), SEQ ID NO : 18 (dominio d de KLH1), SEQ ID NO : 19 (dominio e de KLH1 parcial), SEQ ID NO : 54 (dominio e' de KLH1), SEQ ID NO : 55 (dominio f de KLH1), SEQ ID NO : 56 (dominio g de KLH1), SEQ ID NO : 83 (dominio d'' de HtH1), SEQ ID NO : 84 (dominio e'' de HtH1), SEQ ID NO : 86 (dominio g'' de HtH1), SEQ ID NO : 87 (dominio h'' de HtH1), SEQ ID NO : 55 (dominio f de KLH1), SEQ ID NO : 56 (dominio g de KLH1), SEQ ID NO : 96 (dominio b'' de KLH1 parcial), SEQ ID NO : 97 (dominio c'' de KLH1), SEQ ID NO : 98 (dominio d'' de KLH1), SEQ ID NO : 99 (dominio e'' de KLH1), SEQ ID NO : 100 (dominio f'' de KLH1), y SEQ ID NO : 101 (dominio g'' de KLH1); (b) secuencias de ácido nucleico, que codifican para un polipéptido que comprende al menos una secuencia de aminoácidos seleccionada del siguiente grupo: SEQ ID NO : 28 (dominio d de HtH1), SEQ ID NO : 29 (dominio e de HtH1), SEQ ID NO : 31 (dominio g de HtH1), SEQ ID NO : 32 (dominio h de HtH1), SEQ ID NO : 40 (dominio b de KLH1 parcial), SEQ ID NO : 41 (dominio c de KLH1), SEQ ID NO : 42 (dominio d de KLH1 parcial), SEQ ID NO : 43 (dominio e de KLH1 parcial), SEQ ID NO : 64 (dominio h' de HtH1), SEQ ID NO : 69 (dominio b' de KLH1 parcial), SEQ ID NO : 70 (dominio e' de KLH1), SEQ ID NO : 71 (5 dominio f de KLH1), SEQ ID NO : 72 (dominio g de KLH1), y SEQ ID NO : 73 (dominio h de KLH1); o (c) secuencias de ácido nucleico, que codifican para un polipéptido, cuya secuencia es homóloga en al menos el 60% con una secuencia de la reivindicación 1 (b) a lo largo de una región parcial, calculándose la homología de secuencia a lo largo de al menos 90 aminoácidos.
Description
Claims (1)
-
imagen1 imagen2 imagen3 imagen4
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19911971A DE19911971A1 (de) | 1999-03-17 | 1999-03-17 | Nukleinsäuremolekül, umfassend eine für ein Hämocyanin kodierende Nukleinsäuresequenz |
| DE19911971 | 1999-03-17 | ||
| DE19939578 | 1999-08-20 | ||
| DE19939578A DE19939578A1 (de) | 1999-08-20 | 1999-08-20 | Nukleinsäuremolekül, umfassend eine für ein Hämocyanin kodierende Nukleinsäuresequenz |
| PCT/EP2000/002410 WO2000055192A2 (de) | 1999-03-17 | 2000-03-17 | Hämocyanin und dafür kodierende nukleinsäuresequenz |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2552598T3 true ES2552598T3 (es) | 2015-11-30 |
Family
ID=26052420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES00918811.1T Expired - Lifetime ES2552598T3 (es) | 1999-03-17 | 2000-03-17 | Hemocianina y secuencia de ácido nucleico que codifica para la misma |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7125556B1 (es) |
| EP (1) | EP1218405B1 (es) |
| AU (1) | AU3962700A (es) |
| CA (1) | CA2365451A1 (es) |
| CY (1) | CY1116756T1 (es) |
| DK (1) | DK1218405T3 (es) |
| ES (1) | ES2552598T3 (es) |
| PT (1) | PT1218405E (es) |
| WO (1) | WO2000055192A2 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1218405E (pt) | 1999-03-17 | 2015-11-23 | Biosyn Arzneimittel Gmbh | Hemocianina e sequência de ácidos nucleicos codificante para hemocianina |
| DE19939578A1 (de) | 1999-08-20 | 2001-02-22 | Biosyn Arzneimittel Gmbh | Nukleinsäuremolekül, umfassend eine für ein Hämocyanin kodierende Nukleinsäuresequenz |
| US20040241695A1 (en) * | 2001-09-06 | 2004-12-02 | Frey Mark J | Hemocyanin nucleic acids and polypeptides and related vectors fusion protein conjugates cells and methods of use |
| WO2009129561A1 (en) * | 2008-04-21 | 2009-10-29 | Marine Biotechnology Pty Limited | Anti-viral nutraceutical |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2598147B1 (fr) * | 1986-04-30 | 1988-08-26 | Pasteur Institut | Immunogene isole de mollusques, son procede de preparation, reactifs de diagnostic des bilharzioses humaines, vaccins contre les schistosomiases et compositions immunisantes comprenant ledit immunogene. |
| FR2601021B2 (fr) | 1986-07-07 | 1988-11-18 | Pasteur Institut | Fraction immunogene active a l'egard des bilharzioses, sa preparation, compositions immunisantes la contenant |
| ATE275191T1 (de) * | 1992-11-09 | 2004-09-15 | Zonagen Inc | Methoden für die immunoempfängnisverhütung |
| US5407912A (en) * | 1993-04-19 | 1995-04-18 | Akzo, N.V. | Method of treating bladder cancer with a keyhole limpet hemocyanin composition with enhanced anti-tumor activity |
| US5888775A (en) * | 1994-04-29 | 1999-03-30 | Dade International Inc | Peptide synthesis and purification by fusion to penI protein or precipitation effective portion thereof |
| US5831033A (en) * | 1997-02-14 | 1998-11-03 | Children's Medical Center Of Boston | Human thymosin β15 gene, protein and uses thereof |
| PT1218405E (pt) | 1999-03-17 | 2015-11-23 | Biosyn Arzneimittel Gmbh | Hemocianina e sequência de ácidos nucleicos codificante para hemocianina |
-
2000
- 2000-03-17 PT PT918811T patent/PT1218405E/pt unknown
- 2000-03-17 US US09/936,852 patent/US7125556B1/en not_active Expired - Lifetime
- 2000-03-17 AU AU39627/00A patent/AU3962700A/en not_active Abandoned
- 2000-03-17 WO PCT/EP2000/002410 patent/WO2000055192A2/de not_active Ceased
- 2000-03-17 DK DK00918811.1T patent/DK1218405T3/en active
- 2000-03-17 ES ES00918811.1T patent/ES2552598T3/es not_active Expired - Lifetime
- 2000-03-17 CA CA002365451A patent/CA2365451A1/en not_active Abandoned
- 2000-03-17 EP EP00918811.1A patent/EP1218405B1/de not_active Expired - Lifetime
-
2006
- 2006-08-29 US US11/511,952 patent/US7282578B2/en not_active Expired - Lifetime
-
2015
- 2015-10-05 CY CY20151100884T patent/CY1116756T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1116756T1 (el) | 2017-03-15 |
| US7125556B1 (en) | 2006-10-24 |
| EP1218405A2 (de) | 2002-07-03 |
| PT1218405E (pt) | 2015-11-23 |
| CA2365451A1 (en) | 2000-09-21 |
| US20070077229A1 (en) | 2007-04-05 |
| AU3962700A (en) | 2000-10-04 |
| US7282578B2 (en) | 2007-10-16 |
| WO2000055192A2 (de) | 2000-09-21 |
| WO2000055192A3 (de) | 2002-04-18 |
| DK1218405T3 (en) | 2015-11-02 |
| EP1218405B1 (de) | 2015-08-19 |
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