ES258570A1 - Un procedimiento para preparar una fenotiazina - Google Patents
Un procedimiento para preparar una fenotiazinaInfo
- Publication number
- ES258570A1 ES258570A1 ES0258570A ES258570A ES258570A1 ES 258570 A1 ES258570 A1 ES 258570A1 ES 0258570 A ES0258570 A ES 0258570A ES 258570 A ES258570 A ES 258570A ES 258570 A1 ES258570 A1 ES 258570A1
- Authority
- ES
- Spain
- Prior art keywords
- alkylene
- reacting
- phenothiazine
- acyl
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 alkylene halide Chemical class 0.000 abstract 6
- 229950000688 phenothiazine Drugs 0.000 abstract 4
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- GLUUGHFHXGJENI-UHFFFAOYSA-N diethylenediamine Natural products C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- WJFKNYWRSNBZNX-UHFFFAOYSA-N 10H-phenothiazine Chemical compound C1=CC=C2NC3=CC=CC=C3SC2=C1 WJFKNYWRSNBZNX-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 150000000994 L-ascorbates Chemical class 0.000 abstract 1
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 abstract 1
- KEAYESYHFKHZAL-UHFFFAOYSA-N Sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 abstract 1
- 235000010323 ascorbic acid Nutrition 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 229940113088 dimethylacetamide Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000002814 niacins Chemical class 0.000 abstract 1
- 235000001968 nicotinic acid Nutrition 0.000 abstract 1
- 229910000104 sodium hydride Inorganic materials 0.000 abstract 1
- 239000012312 sodium hydride Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un procedimiento para preparar una fenotiazina que tenga la estructura: *** ver imagen 01 en la que A representa un radical alcohileno de 2 a 5 átomos de carbono. R es un radical alcohilo inferior de 1 a 4 átomos de carbono y R1 es un radical alcohilo inferior hidroxi-sustituido que tenga de 1 a 4 átomos de carbono, que comprende la condensación en presencia de un agente condensante alcalino, como el sodio metálico, sodamida, o hidruro de sodio de una fenotiazina que tenga la estructura: *** ver imagen 02
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81774059A | 1959-06-03 | 1959-06-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES258570A1 true ES258570A1 (es) | 1960-11-16 |
Family
ID=25223778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0258570A Expired ES258570A1 (es) | 1959-06-03 | 1960-06-02 | Un procedimiento para preparar una fenotiazina |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE590867A (es) |
| CH (1) | CH402864A (es) |
| ES (1) | ES258570A1 (es) |
| FR (1) | FR235M (es) |
| GB (1) | GB900755A (es) |
-
1960
- 1960-05-16 BE BE590867A patent/BE590867A/fr unknown
- 1960-06-02 CH CH632060A patent/CH402864A/de unknown
- 1960-06-02 ES ES0258570A patent/ES258570A1/es not_active Expired
- 1960-06-02 GB GB19532/60A patent/GB900755A/en not_active Expired
- 1960-08-23 FR FR836527A patent/FR235M/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CH402864A (de) | 1965-11-30 |
| GB900755A (en) | 1962-07-11 |
| BE590867A (fr) | 1960-11-16 |
| FR235M (fr) | 1961-02-27 |
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