ES2629309T3 - Formulaciones de tratamiento de la mucositis inducida por terapia antitumoral o inmunosupresora - Google Patents
Formulaciones de tratamiento de la mucositis inducida por terapia antitumoral o inmunosupresora Download PDFInfo
- Publication number
- ES2629309T3 ES2629309T3 ES09700368.5T ES09700368T ES2629309T3 ES 2629309 T3 ES2629309 T3 ES 2629309T3 ES 09700368 T ES09700368 T ES 09700368T ES 2629309 T3 ES2629309 T3 ES 2629309T3
- Authority
- ES
- Spain
- Prior art keywords
- treatment
- formulations
- antitumor
- immunosuppressive therapy
- mucositis induced
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 206010028116 Mucosal inflammation Diseases 0.000 title abstract 2
- 201000010927 Mucositis Diseases 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000000259 anti-tumor effect Effects 0.000 title 1
- 238000002650 immunosuppressive therapy Methods 0.000 title 1
- INVGWHRKADIJHF-UHFFFAOYSA-N Sanguinarin Chemical compound C1=C2OCOC2=CC2=C3[N+](C)=CC4=C(OCO5)C5=CC=C4C3=CC=C21 INVGWHRKADIJHF-UHFFFAOYSA-N 0.000 abstract 2
- FLZGFQFYDGHWLR-UHFFFAOYSA-N luteic acid Chemical class O1C(=O)C2=CC(O)=C(O)C(O)=C2C2=C1C(O)=C(O)C=C2C(=O)O FLZGFQFYDGHWLR-UHFFFAOYSA-N 0.000 abstract 2
- FCEXWTOTHXCQCQ-UHFFFAOYSA-N Ethoxydihydrosanguinarine Natural products C12=CC=C3OCOC3=C2C(OCC)N(C)C(C2=C3)=C1C=CC2=CC1=C3OCO1 FCEXWTOTHXCQCQ-UHFFFAOYSA-N 0.000 abstract 1
- 229920001884 Luteic acid Polymers 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940084560 sanguinarine Drugs 0.000 abstract 1
- YZRQUTZNTDAYPJ-UHFFFAOYSA-N sanguinarine pseudobase Natural products C1=C2OCOC2=CC2=C3N(C)C(O)C4=C(OCO5)C5=CC=C4C3=CC=C21 YZRQUTZNTDAYPJ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60S—SERVICING, CLEANING, REPAIRING, SUPPORTING, LIFTING, OR MANOEUVRING OF VEHICLES, NOT OTHERWISE PROVIDED FOR
- B60S3/00—Vehicle cleaning apparatus not integral with vehicles
- B60S3/04—Vehicle cleaning apparatus not integral with vehicles for exteriors of land vehicles
- B60S3/06—Vehicle cleaning apparatus not integral with vehicles for exteriors of land vehicles with rotary bodies contacting the vehicle
- B60S3/063—Vehicle cleaning apparatus not integral with vehicles for exteriors of land vehicles with rotary bodies contacting the vehicle the axis of rotation being approximately vertical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Mechanical Engineering (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Formulaciones que contienen sanguinarina o queleritrina en forma de sales de ácido luteico en mezcla con vehículos y/o excipientes adecuados para su uso en el tratamiento y/o la prevención de la mucositis.
Description
Claims (1)
-
imagen1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000038A ITMI20080038A1 (it) | 2008-01-11 | 2008-01-11 | Formulazioni per il trattamento di mucositi indotte da terapia antitumorale o immunosoppressiva |
| ITMI20080038 | 2008-01-11 | ||
| PCT/EP2009/000050 WO2009087091A2 (en) | 2008-01-11 | 2009-01-08 | Formulations for the treatment of mucositis induced by antitumor or immunosuppressive therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2629309T3 true ES2629309T3 (es) | 2017-08-08 |
Family
ID=40290063
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09700368.5T Active ES2629309T3 (es) | 2008-01-11 | 2009-01-08 | Formulaciones de tratamiento de la mucositis inducida por terapia antitumoral o inmunosupresora |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US8940338B2 (es) |
| EP (1) | EP2231158B1 (es) |
| JP (1) | JP5357896B2 (es) |
| KR (1) | KR20100100953A (es) |
| CN (1) | CN101917997A (es) |
| AU (1) | AU2009203819B2 (es) |
| CA (1) | CA2711840C (es) |
| DK (1) | DK2231158T3 (es) |
| ES (1) | ES2629309T3 (es) |
| HU (1) | HUE035036T2 (es) |
| IL (1) | IL206881A (es) |
| IT (1) | ITMI20080038A1 (es) |
| PL (1) | PL2231158T3 (es) |
| PT (1) | PT2231158T (es) |
| RU (1) | RU2460535C2 (es) |
| SI (1) | SI2231158T1 (es) |
| WO (1) | WO2009087091A2 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007011825A2 (en) | 2005-07-19 | 2007-01-25 | Texas Enterosorbent, Inc. | Preservative and additive for food and feed |
| US20100190735A1 (en) * | 2006-03-28 | 2010-07-29 | Myrex Pharmaceuticals Inc. | Mouthwash and Method of Using Same for the Treatment of Mucositis or Stomatitis |
| US9597313B2 (en) | 2006-06-27 | 2017-03-21 | Timothy D. Phillips | Composition and methods for the enterosorption and management of toxins |
| CN101904849A (zh) * | 2010-08-19 | 2010-12-08 | 苏州大学 | 血根碱制备肿瘤放射治疗增敏药物的应用 |
| WO2013059827A1 (en) * | 2011-10-20 | 2013-04-25 | Salient Pharmaceuticals, Inc. | Methods and compositions for treating mucositis |
| AT515336A1 (de) * | 2014-02-03 | 2015-08-15 | Roth Hermann Dr | Vermeidung oxidativer Prozesse und oxidativem Stress |
| JP7096332B2 (ja) * | 2017-07-31 | 2022-07-05 | ムコサ イノバティオンズ,エセ エレ | 腫瘍処置誘導性の経口胃腸粘膜炎の予防および/または処置における使用のための組成物 |
| KR102893442B1 (ko) * | 2022-12-23 | 2025-12-01 | 가톨릭대학교 산학협력단 | 켈레리트린 클로라이드 또는 그의 약제학적으로 허용가능한 염을 유효성분으로 포함하는 암 예방 또는 치료용 약학적 조성물 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1254321B (it) * | 1992-04-10 | 1995-09-14 | Kemiprogress S R L | Composizione farmaceutica per il trattamento e la prevenzione delle infiammazioni cutanee e della mucosa orale. |
| JP2000109428A (ja) * | 1998-10-05 | 2000-04-18 | Taisho Pharmaceut Co Ltd | 咽頭粘膜用組成物 |
| ITMI20042414A1 (it) | 2004-12-17 | 2005-03-17 | Indena Spa | Formulazione per il trattamento di affezioni delle prime vie respiratorie |
| US7491414B2 (en) * | 2005-10-12 | 2009-02-17 | Gaia Herbs, Inc. | Anti-inflammatory substances extracted from Echinacea |
| EP1882473A1 (en) * | 2006-07-28 | 2008-01-30 | Indena S.P.A. | Use of anthocyanosides to prepare formulations for the treatment of mucositis induced by antitumoral drugs |
| ITMI20080284A1 (it) * | 2008-02-22 | 2009-08-23 | Indena Spa | Agenti antitumorali a struttura benzofenantridinica e formulazioni che li contengono |
-
2008
- 2008-01-11 IT IT000038A patent/ITMI20080038A1/it unknown
-
2009
- 2009-01-08 AU AU2009203819A patent/AU2009203819B2/en not_active Ceased
- 2009-01-08 RU RU2010128171/15A patent/RU2460535C2/ru not_active IP Right Cessation
- 2009-01-08 HU HUE09700368A patent/HUE035036T2/en unknown
- 2009-01-08 PL PL09700368T patent/PL2231158T3/pl unknown
- 2009-01-08 CN CN2009801018866A patent/CN101917997A/zh active Pending
- 2009-01-08 WO PCT/EP2009/000050 patent/WO2009087091A2/en not_active Ceased
- 2009-01-08 SI SI200931657A patent/SI2231158T1/sl unknown
- 2009-01-08 EP EP09700368.5A patent/EP2231158B1/en not_active Not-in-force
- 2009-01-08 KR KR1020107015077A patent/KR20100100953A/ko not_active Ceased
- 2009-01-08 US US12/812,065 patent/US8940338B2/en not_active Expired - Fee Related
- 2009-01-08 DK DK09700368.5T patent/DK2231158T3/en active
- 2009-01-08 CA CA2711840A patent/CA2711840C/en not_active Expired - Fee Related
- 2009-01-08 PT PT97003685T patent/PT2231158T/pt unknown
- 2009-01-08 ES ES09700368.5T patent/ES2629309T3/es active Active
- 2009-01-08 JP JP2010541748A patent/JP5357896B2/ja not_active Expired - Fee Related
-
2010
- 2010-07-08 IL IL206881A patent/IL206881A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| US20100284945A1 (en) | 2010-11-11 |
| EP2231158A2 (en) | 2010-09-29 |
| ITMI20080038A1 (it) | 2009-07-12 |
| SI2231158T1 (sl) | 2017-06-30 |
| KR20100100953A (ko) | 2010-09-15 |
| WO2009087091A2 (en) | 2009-07-16 |
| RU2460535C2 (ru) | 2012-09-10 |
| CA2711840A1 (en) | 2009-07-16 |
| AU2009203819A1 (en) | 2009-07-16 |
| US8940338B2 (en) | 2015-01-27 |
| DK2231158T3 (en) | 2017-06-12 |
| RU2010128171A (ru) | 2012-01-20 |
| JP5357896B2 (ja) | 2013-12-04 |
| EP2231158B1 (en) | 2017-04-05 |
| WO2009087091A3 (en) | 2009-11-26 |
| WO2009087091A8 (en) | 2009-10-08 |
| AU2009203819B2 (en) | 2014-07-31 |
| IL206881A (en) | 2015-09-24 |
| CA2711840C (en) | 2014-02-18 |
| PT2231158T (pt) | 2017-07-03 |
| IL206881A0 (en) | 2010-12-30 |
| CN101917997A (zh) | 2010-12-15 |
| PL2231158T3 (pl) | 2017-09-29 |
| HUE035036T2 (en) | 2018-05-02 |
| JP2011509270A (ja) | 2011-03-24 |
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