CL2013002003A1 - Compuestos derivados de 1, 2, 4-triazolo [4,3-a] quinoxalina, inhibidores de pde2 y/o 10; composicion farmaceutica que los comprende; combinacion farmaceutica; y su uso para en el trastamiento de enfermedades del snc - Google Patents

Compuestos derivados de 1, 2, 4-triazolo [4,3-a] quinoxalina, inhibidores de pde2 y/o 10; composicion farmaceutica que los comprende; combinacion farmaceutica; y su uso para en el trastamiento de enfermedades del snc

Info

Publication number: CL2013002003A1
Authority: CL; Chile
Prior art keywords: pde2; triazolo; quinoxaline; cns; inhibitors
Prior art date: 2011-01-31

Application number

CL2013002003A

Other languages

English (en)

Inventor

Hans-Joachim Lankau

Barbara Langen

Norbert Hofgen

Hans Stange

Rita Dost

Ute Egerland

Christian Grunwald

Original Assignee

Boehringer Ingelheim Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-01-31

Filing date

2013-07-08

Publication date

2013-12-06

2013-07-08 Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int

2013-12-06 Publication of CL2013002003A1 publication Critical patent/CL2013002003A1/es

Links

101100135859 Dictyostelium discoideum regA gene Proteins 0.000 title 1
QNSRYVDGWDXBHV-UHFFFAOYSA-N [1,2,4]triazolo[4,3-a]quinoxaline Chemical compound C1=CC=C2N3C=NN=C3C=NC2=C1 QNSRYVDGWDXBHV-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
201000010099 disease Diseases 0.000 title 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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- A61K31/33—Heterocyclic compounds
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Addiction (AREA)
Psychiatry (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Hematology (AREA)
Obesity (AREA)
Reproductive Health (AREA)
Pain & Pain Management (AREA)
Gynecology & Obstetrics (AREA)
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Urology & Nephrology (AREA)
Child & Adolescent Psychology (AREA)
Vascular Medicine (AREA)
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Ophthalmology & Optometry (AREA)
Pregnancy & Childbirth (AREA)
Heart & Thoracic Surgery (AREA)
Orthopedic Medicine & Surgery (AREA)
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CL2013002003A 2011-01-31 2013-07-08 Compuestos derivados de 1, 2, 4-triazolo [4,3-a] quinoxalina, inhibidores de pde2 y/o 10; composicion farmaceutica que los comprende; combinacion farmaceutica; y su uso para en el trastamiento de enfermedades del snc CL2013002003A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US201161437848P	2011-01-31	2011-01-31

Publications (1)

Publication Number	Publication Date
CL2013002003A1 true CL2013002003A1 (es)	2013-12-06

Family

ID=45833359

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CL2013002003A CL2013002003A1 (es)	2011-01-31	2013-07-08	Compuestos derivados de 1, 2, 4-triazolo [4,3-a] quinoxalina, inhibidores de pde2 y/o 10; composicion farmaceutica que los comprende; combinacion farmaceutica; y su uso para en el trastamiento de enfermedades del snc

Country Status (25)

Country	Link
US (1)	US9540379B2 (es)
EP (1)	EP2670754B1 (es)
JP (1)	JP6027547B2 (es)
KR (1)	KR20140019342A (es)
CN (1)	CN103459395A (es)
AR (1)	AR085099A1 (es)
AU (1)	AU2012213471B2 (es)
BR (1)	BR112013019354A2 (es)
CA (1)	CA2824929A1 (es)
CL (1)	CL2013002003A1 (es)
CO (1)	CO6811848A2 (es)
EA (1)	EA023792B1 (es)
EC (1)	ECSP13012824A (es)
GE (1)	GEP20156333B (es)
IL (1)	IL226826A (es)
MA (1)	MA34844B1 (es)
MX (1)	MX2013008667A (es)
PE (1)	PE20141023A1 (es)
PH (1)	PH12013501355A1 (es)
SG (1)	SG192210A1 (es)
TN (1)	TN2013000325A1 (es)
TW (1)	TWI535718B (es)
UA (1)	UA111963C2 (es)
UY (1)	UY33888A (es)
WO (1)	WO2012104293A1 (es)

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JP6115962B2 (ja)	2011-06-27	2017-04-19	ヤンセンファーマシューティカエヌ．ベー．	１−アリール−４−メチル−［１，２，４］トリアゾロ［４，３−ａ］キノキサリン誘導体
US9056863B2 (en)	2011-09-09	2015-06-16	H. Lundbeck A/S	Substituted 2,3,5,9,9B-pentaazacyclopenta[a]naphthalenes and uses thereof
WO2013034758A1 (en)	2011-09-09	2013-03-14	H. Lundbeck A/S	Substituted triazolopyrazines and uses thereof
WO2014001314A1 (en)	2012-06-26	2014-01-03	Janssen Pharmaceutica Nv	Combinations comprising pde 2 inhibitors such as 1-aryl-4-methyl- [1,2,4] triazolo [4,3-a] quinoxaline compounds and pde 10 inhibitors for use in the treatment of neurological or metabolic disorders
US20140045856A1 (en)	2012-07-31	2014-02-13	Boehringer Ingelheim International Gmbh	4-Methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalenes

2012
- 2012-01-30 US US13/361,002 patent/US9540379B2/en active Active
- 2012-01-31 CA CA2824929A patent/CA2824929A1/en not_active Abandoned
- 2012-01-31 EP EP12708774.0A patent/EP2670754B1/en active Active
- 2012-01-31 KR KR1020137023101A patent/KR20140019342A/ko not_active Ceased
- 2012-01-31 AU AU2012213471A patent/AU2012213471B2/en not_active Ceased
- 2012-01-31 JP JP2013550908A patent/JP6027547B2/ja active Active
- 2012-01-31 WO PCT/EP2012/051546 patent/WO2012104293A1/en not_active Ceased
- 2012-01-31 GE GEAP201213211A patent/GEP20156333B/en unknown
- 2012-01-31 MX MX2013008667A patent/MX2013008667A/es active IP Right Grant
- 2012-01-31 EA EA201300871A patent/EA023792B1/ru not_active IP Right Cessation
- 2012-01-31 TW TW101103150A patent/TWI535718B/zh not_active IP Right Cessation
- 2012-01-31 PE PE2013001585A patent/PE20141023A1/es not_active Application Discontinuation
- 2012-01-31 BR BR112013019354A patent/BR112013019354A2/pt not_active IP Right Cessation
- 2012-01-31 MA MA36142A patent/MA34844B1/fr unknown
- 2012-01-31 SG SG2013057815A patent/SG192210A1/en unknown
- 2012-01-31 CN CN2012800157168A patent/CN103459395A/zh active Pending
- 2012-01-31 UA UAA201310356A patent/UA111963C2/uk unknown
- 2012-01-31 PH PH1/2013/501355A patent/PH12013501355A1/en unknown
- 2012-01-31 AR ARP120100303A patent/AR085099A1/es unknown
- 2012-01-31 UY UY0001033888A patent/UY33888A/es not_active Application Discontinuation
2013
- 2013-06-09 IL IL226826A patent/IL226826A/en not_active IP Right Cessation
- 2013-07-08 CL CL2013002003A patent/CL2013002003A1/es unknown
- 2013-07-29 CO CO13179130A patent/CO6811848A2/es not_active Application Discontinuation
- 2013-07-29 TN TNP2013000325A patent/TN2013000325A1/fr unknown
- 2013-08-13 EC EC2013012824A patent/ECSP13012824A/es unknown

Also Published As

Publication number	Publication date
JP6027547B2 (ja)	2016-11-16
IL226826A (en)	2016-10-31
MX2013008667A (es)	2013-10-01
PE20141023A1 (es)	2014-09-04
JP2014503576A (ja)	2014-02-13
UA111963C2 (uk)	2016-07-11
ECSP13012824A (es)	2013-10-31
KR20140019342A (ko)	2014-02-14
TN2013000325A1 (en)	2015-01-20
AU2012213471A1 (en)	2013-07-04
MA34844B1 (fr)	2014-01-02
PH12013501355A1 (en)	2013-09-02
AU2012213471B2 (en)	2016-07-14
UY33888A (es)	2012-08-31
EA201300871A1 (ru)	2014-01-30
BR112013019354A2 (pt)	2019-09-24
US9540379B2 (en)	2017-01-10
EP2670754B1 (en)	2017-05-24
WO2012104293A1 (en)	2012-08-09
SG192210A1 (en)	2013-09-30
TWI535718B (zh)	2016-06-01
GEP20156333B (en)	2015-07-27
AR085099A1 (es)	2013-09-11
EA023792B1 (ru)	2016-07-29
CA2824929A1 (en)	2012-08-09
CN103459395A (zh)	2013-12-18
EP2670754A1 (en)	2013-12-11
TW201245198A (en)	2012-11-16
NZ611630A (en)	2015-03-27
US20120302564A1 (en)	2012-11-29
CO6811848A2 (es)	2013-12-16

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