ES264795A1 - Un procedimiento para la preparacion de compuestos quimicos de actividad terapeutica - Google Patents

Un procedimiento para la preparacion de compuestos quimicos de actividad terapeutica

Info

Publication number: ES264795A1
Authority: ES; Spain
Prior art keywords: group; compounds; amino; represent hydrogen; groups
Prior art date: 1960-02-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES0264795A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

WILDER SMITH ARTHUR ERNEST

Original Assignee

WILDER SMITH ARTHUR ERNEST

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1960-02-12

Filing date

1961-02-10

Publication date

1961-08-16

1961-02-10 Application filed by WILDER SMITH ARTHUR ERNEST filed Critical WILDER SMITH ARTHUR ERNEST

1961-08-16 Publication of ES264795A1 publication Critical patent/ES264795A1/es

Status Expired legal-status Critical Current

Links

ZVTQYRVARPYRRE-UHFFFAOYSA-N oxadiazol-4-one Chemical class O=C1CON=N1 ZVTQYRVARPYRRE-UHFFFAOYSA-N 0.000 title abstract 2
JNGDFYLGDPAEBY-UHFFFAOYSA-N oxadiazole-4-thione Chemical class S=C1CON=N1 JNGDFYLGDPAEBY-UHFFFAOYSA-N 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 12
229910052739 hydrogen Inorganic materials 0.000 abstract 8
239000001257 hydrogen Substances 0.000 abstract 8
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 6
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical group C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 3
239000002253 acid Substances 0.000 abstract 3
-1 acylamido Chemical group 0.000 abstract 3
125000004423 acyloxy group Chemical group 0.000 abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 3
125000003277 amino group Chemical group 0.000 abstract 3
125000003710 aryl alkyl group Chemical group 0.000 abstract 3
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 3
125000002462 isocyano group Chemical group *[N+]#[C-] 0.000 abstract 3
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 3
229910052760 oxygen Inorganic materials 0.000 abstract 3
239000001301 oxygen Substances 0.000 abstract 3
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
150000003839 salts Chemical class 0.000 abstract 3
OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 2
YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical group C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical group C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical group C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical group C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 abstract 2
SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical group N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 abstract 2
125000002252 acyl group Chemical group 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000002877 alkyl aryl group Chemical group 0.000 abstract 2
125000003118 aryl group Chemical group 0.000 abstract 2
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
150000002148 esters Chemical class 0.000 abstract 2
125000005843 halogen group Chemical group 0.000 abstract 2
150000002431 hydrogen Chemical group 0.000 abstract 2
125000004356 hydroxy functional group Chemical group O* 0.000 abstract 2
239000000203 mixture Substances 0.000 abstract 2
QQOXBFUTRLDXDP-UHFFFAOYSA-N p-Aminosalicylic acid methyl ester Chemical compound COC(=O)C1=CC=C(N)C=C1O QQOXBFUTRLDXDP-UHFFFAOYSA-N 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
239000000376 reactant Substances 0.000 abstract 2
230000001225 therapeutic effect Effects 0.000 abstract 2
125000002813 thiocarbonyl group Chemical group *C(*)=S 0.000 abstract 2
YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 1
CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical group C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 abstract 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
WETWJCDKMRHUPV-UHFFFAOYSA-N acetyl chloride Chemical compound CC(Cl)=O WETWJCDKMRHUPV-UHFFFAOYSA-N 0.000 abstract 1
239000012346 acetyl chloride Substances 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
125000003368 amide group Chemical group 0.000 abstract 1
230000000202 analgesic effect Effects 0.000 abstract 1
239000002260 anti-inflammatory agent Substances 0.000 abstract 1
230000001741 anti-phlogistic effect Effects 0.000 abstract 1
230000001754 anti-pyretic effect Effects 0.000 abstract 1
239000002221 antipyretic Substances 0.000 abstract 1
150000001733 carboxylic acid esters Chemical group 0.000 abstract 1
150000001735 carboxylic acids Chemical class 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
238000010438 heat treatment Methods 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
230000007062 hydrolysis Effects 0.000 abstract 1
238000006460 hydrolysis reaction Methods 0.000 abstract 1
230000003301 hydrolyzing effect Effects 0.000 abstract 1
229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
239000012948 isocyanate Substances 0.000 abstract 1
150000002513 isocyanates Chemical class 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
LCXHOHRQXZMSQN-UHFFFAOYSA-N methyl 4-acetamido-2-hydroxybenzoate Chemical compound COC(=O)C1=CC=C(NC(C)=O)C=C1O LCXHOHRQXZMSQN-UHFFFAOYSA-N 0.000 abstract 1
239000011707 mineral Substances 0.000 abstract 1
238000007911 parenteral administration Methods 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
JEXVQSWXXUJEMA-UHFFFAOYSA-N pyrazol-3-one Chemical class O=C1C=CN=N1 JEXVQSWXXUJEMA-UHFFFAOYSA-N 0.000 abstract 1
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Chemical group COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
150000003248 quinolines Chemical group 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
ZWZVWGITAAIFPS-UHFFFAOYSA-N thiophosgene Chemical compound ClC(Cl)=S ZWZVWGITAAIFPS-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES0264795A 1960-02-12 1961-02-10 Un procedimiento para la preparacion de compuestos quimicos de actividad terapeutica Expired ES264795A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB5180/60A GB966972A (en)	1960-02-12	1960-02-12	Substituted oxadiazolones and oxadiazolthiones

Publications (1)

Publication Number	Publication Date
ES264795A1 true ES264795A1 (es)	1961-08-16

Family

ID=9791203

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES0264795A Expired ES264795A1 (es)	1960-02-12	1961-02-10	Un procedimiento para la preparacion de compuestos quimicos de actividad terapeutica

Country Status (4)

Country	Link
AT (1)	AT241457B (de)
BE (1)	BE600071A (de)
ES (1)	ES264795A1 (de)
GB (1)	GB966972A (de)

1960
- 1960-02-12 GB GB5180/60A patent/GB966972A/en not_active Expired
1961
- 1961-02-10 BE BE600071A patent/BE600071A/fr unknown
- 1961-02-10 ES ES0264795A patent/ES264795A1/es not_active Expired
- 1961-02-13 AT AT119061A patent/AT241457B/de active

Also Published As

Publication number	Publication date
AT241457B (de)	1965-07-26
BE600071A (fr)	1961-08-10
GB966972A (en)	1964-08-19

Publication	Publication Date	Title
ES431056A1 (es)	1976-10-16	Procedimiento para la preparacion de nuevos n- (metoximetil-furilmetil)-6, 7-benzomorfanos y -morfinanos.
SE340459B (de)	1971-11-22
GB1386865A (en)	1975-03-12	Phosphorinane derivatives and lubricant compositions containing them
GB899842A (en)	1962-06-27	Process for producing 1:3:4-thiadiazines having aromatic substituents
GB1161801A (en)	1969-08-20	1,3,4-Oxadiazoles
ES347178A1 (es)	1969-01-16	Procedimiento para la preparacion de nuevas amidas de aci- do.
ES437151A1 (es)	1977-01-16	Procedimiento para la produccion de derivados de xantina.
ES264795A1 (es)	1961-08-16	Un procedimiento para la preparacion de compuestos quimicos de actividad terapeutica
ES479570A1 (es)	1979-12-01	Un procedimiento para la preparacion de derivaciones 7 &-me-toxicefalosporina.
ES448721A1 (es)	1977-07-16	Un procedimiento para la produccion de compuestos amidicos antibacterianos.
GB1087174A (en)	1967-10-11	Piperidine derivatives
ES296381A1 (es)	1964-04-16	Procedimiento para la obtención de nuevos compuestos polibásicos
GB1287753A (en)	1972-09-06	Substituted anilides and preparations containing them
GB1123466A (en)	1968-08-14	Process for the production of cyanamide dicarboxylic acid esters
ES440532A1 (es)	1977-03-01	Procedimiento para la preparacion de derivados de 3-hidroxi-1, 2, 4-triazol.
ES437081A1 (es)	1977-01-16	Procedimiento para la preparacion de nuevas 1-(n-(para-fluo-robenzoilpropil)-4-piperidil)-ureas.
GB989951A (en)	1965-04-22	Anti-inflammatory pharmaceutical compositions containing n-phenyl anthranilic acid derivatives
ES393554A1 (es)	1974-11-16	Un procedimiento para la preparacion de derivados de tia- zol.
GB1428187A (en)	1976-03-17	6-aminopenicillanic acid derivatives and process for the preparation of the same
ES278797A1 (es)	1963-03-16	Procedimiento para la preparaciën de nuevos fenil-uracilos
ES378249A1 (es)	1972-05-16	Procedimiento para la obtencion de derivados de n-(tiono) fosforil y (tiono) fosfonil - 3 - metil - 5 - hidroxipara- zol.
GB854950A (en)	1960-11-23	Process for the production of heterocyclic carboxylic acids of the pyrazole series, as well as their esters and salts
ES427582A1 (es)	1976-07-16	Metodo para la preparacion de derivados del acido benzoil- benzoico.
ES377921A1 (es)	1972-10-16	Procedimiento para la preparacion de derivados del acido adamantilcarboxamidofenilacetico.
ES301710A1 (es)	1964-09-16	Procedimiento para la preparación de nuevas 1,2-diaril-4-alquil-3,5-dioxo-pirazolidinas