ES2649492T3 - (S)-pirlindol o sus sales farmacéuticamente aceptables para uso en medicina - Google Patents

(S)-pirlindol o sus sales farmacéuticamente aceptables para uso en medicina Download PDF

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Publication number
ES2649492T3
ES2649492T3 ES14726444.4T ES14726444T ES2649492T3 ES 2649492 T3 ES2649492 T3 ES 2649492T3 ES 14726444 T ES14726444 T ES 14726444T ES 2649492 T3 ES2649492 T3 ES 2649492T3
Authority
ES
Spain
Prior art keywords
pirlindole
pharmaceutically acceptable
pain
enantiomer
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES14726444.4T
Other languages
English (en)
Spanish (es)
Inventor
Augusto Eugénio PARDAL FILIPE
Pedro Filipe EUFRÁSIO PEDROSO
Susana Marques ALMEIDA PECORELLI
Carlos Alberto Eufrásio CASIMIRO CAIXADO
Ana Sofia da Conceição LOPES
João Carlos DAMIL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tecnimede Sociedade Tecnico Medicinal SA
Original Assignee
Tecnimede Sociedade Tecnico Medicinal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tecnimede Sociedade Tecnico Medicinal SA filed Critical Tecnimede Sociedade Tecnico Medicinal SA
Application granted granted Critical
Publication of ES2649492T3 publication Critical patent/ES2649492T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Furan Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Saccharide Compounds (AREA)
ES14726444.4T 2014-05-09 2014-05-09 (S)-pirlindol o sus sales farmacéuticamente aceptables para uso en medicina Active ES2649492T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/PT2014/000029 WO2015171005A1 (en) 2014-05-09 2014-05-09 (s)-pirlindole or its pharmaceutically acceptable salts for use in medicine

Publications (1)

Publication Number Publication Date
ES2649492T3 true ES2649492T3 (es) 2018-01-12

Family

ID=50819931

Family Applications (1)

Application Number Title Priority Date Filing Date
ES14726444.4T Active ES2649492T3 (es) 2014-05-09 2014-05-09 (S)-pirlindol o sus sales farmacéuticamente aceptables para uso en medicina

Country Status (30)

Country Link
US (1) US9814712B2 (sr)
EP (1) EP3057589B1 (sr)
JP (1) JP6768520B2 (sr)
KR (1) KR102298676B1 (sr)
CN (1) CN106456637B (sr)
AU (1) AU2014393490B2 (sr)
CA (1) CA2948598C (sr)
CY (1) CY1119532T1 (sr)
DK (1) DK3057589T3 (sr)
EC (1) ECSP16086247A (sr)
ES (1) ES2649492T3 (sr)
HR (1) HRP20171651T1 (sr)
HU (1) HUE035071T2 (sr)
IL (1) IL248855B (sr)
LT (1) LT3057589T (sr)
MA (1) MA39447B1 (sr)
MX (1) MX368734B (sr)
NO (1) NO3057589T3 (sr)
NZ (1) NZ726132A (sr)
PH (1) PH12016502233A1 (sr)
PL (1) PL3057589T3 (sr)
PT (1) PT3057589T (sr)
RS (1) RS56591B1 (sr)
RU (1) RU2695647C2 (sr)
SA (1) SA516380264B1 (sr)
SI (1) SI3057589T1 (sr)
SM (1) SMT201700519T1 (sr)
TN (1) TN2016000498A1 (sr)
UA (1) UA118474C2 (sr)
WO (1) WO2015171005A1 (sr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SMT202400359T1 (it) * 2014-05-09 2024-11-15 Tecnimede Sociedade Tecnico Medicinal S Sali mandelati degli enantiomeri del pirlindolo per l'uso in medicina
TN2016000497A1 (en) 2014-05-09 2018-04-04 Tecnimede Sociedade Tecnico Medicinal S (r)-pirlindole and its pharmaceutically acceptable salts for use in medicine
EP3392251A1 (en) 2017-04-21 2018-10-24 Tecnimede-Sociedade Tecnico-Medicinal, S.A. Process for the preparation of pirlindole enantiomers and its salts
EP3392250A1 (en) * 2017-04-21 2018-10-24 Tecnimede-Sociedade Tecnico-Medicinal, S.A. Process for the preparation of piperazine ring for the synthesis of pyrazinocarbazole derivatives
MX2018011142A (es) 2018-09-13 2019-10-10 Federico Amezcua Amezcua Combinacion farmaceutica sinergica de un inhibidor selectivo de la ciclooxigenasa 2 y un derivado de antraquinona.
EP3900716A1 (en) * 2020-04-21 2021-10-27 Dompe' Farmaceutici S.P.A. Co-crystal of gabapentin, ketoprofen and lysine, pharmaceutical compositions and their medical use
CN117717546A (zh) * 2023-10-20 2024-03-19 四川大学华西医院 一种吲哚类衍生物在制备预防和/或治疗疼痛的药物中的用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1558231A4 (en) * 2002-10-03 2010-09-08 Cypress Bioscience Inc DOSAGE CLIMBING AND FRICTIONAL DAILY DOSE OF ANTIDEPRESSANTS TO TREAT NEUROLOGICAL DISORDERS
AU2003292936A1 (en) * 2002-12-24 2004-07-22 Neurochem (International) Limited Therapeutic formulations for the treatment of beta-amyloid related diseases
JP2007505831A (ja) * 2003-09-15 2007-03-15 ベクトゥラ・リミテッド 肺吸入による、早漏を治療するための医薬品組成物
EP1688161A1 (en) * 2004-11-02 2006-08-09 Switch Biotech Aktiengesellschaft Use of pirlindole for the treatment of diseases which are characterized by proliferation of t-lymphocytes and/or hyperproliferation of keratinocytes in particular atopic dermatitis and psoriasis
SMT202400359T1 (it) * 2014-05-09 2024-11-15 Tecnimede Sociedade Tecnico Medicinal S Sali mandelati degli enantiomeri del pirlindolo per l'uso in medicina

Also Published As

Publication number Publication date
CN106456637A (zh) 2017-02-22
SMT201700519T1 (it) 2018-01-11
EP3057589A1 (en) 2016-08-24
JP6768520B2 (ja) 2020-10-14
WO2015171005A1 (en) 2015-11-12
CN106456637B (zh) 2020-06-09
KR102298676B1 (ko) 2021-09-07
CA2948598A1 (en) 2015-11-12
MX2016014699A (es) 2017-05-02
UA118474C2 (uk) 2019-01-25
NO3057589T3 (sr) 2017-12-30
HUE035071T2 (en) 2018-05-02
PH12016502233A1 (en) 2017-02-06
SI3057589T1 (sl) 2017-12-29
EP3057589B1 (en) 2017-08-02
RU2016148183A (ru) 2018-06-13
HRP20171651T1 (hr) 2017-12-15
RU2016148183A3 (sr) 2018-06-13
RS56591B1 (sr) 2018-02-28
US9814712B2 (en) 2017-11-14
MX368734B (es) 2019-10-14
PL3057589T3 (pl) 2018-01-31
CY1119532T1 (el) 2018-03-07
NZ726132A (en) 2019-02-22
TN2016000498A1 (en) 2018-04-04
US20170143709A1 (en) 2017-05-25
LT3057589T (lt) 2017-11-27
ECSP16086247A (es) 2017-02-24
RU2695647C2 (ru) 2019-07-25
IL248855A0 (en) 2017-01-31
KR20170002434A (ko) 2017-01-06
JP2017518979A (ja) 2017-07-13
CA2948598C (en) 2021-06-08
MA39447A1 (fr) 2017-10-31
SA516380264B1 (ar) 2019-07-29
AU2014393490B2 (en) 2020-01-02
PT3057589T (pt) 2017-11-29
DK3057589T3 (da) 2017-11-13
IL248855B (en) 2020-05-31
MA39447B1 (fr) 2018-05-31
AU2014393490A1 (en) 2016-11-24

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