ES2653667T3 - Péptidos anfifílicos para la oclusión del escape de aire torácico - Google Patents

Péptidos anfifílicos para la oclusión del escape de aire torácico Download PDF

Info

Publication number
ES2653667T3
ES2653667T3 ES12828087.2T ES12828087T ES2653667T3 ES 2653667 T3 ES2653667 T3 ES 2653667T3 ES 12828087 T ES12828087 T ES 12828087T ES 2653667 T3 ES2653667 T3 ES 2653667T3
Authority
ES
Spain
Prior art keywords
peptide
occlusion
air leak
amphiphilic peptides
aqueous solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES12828087.2T
Other languages
English (en)
Inventor
Satoru Kobayashi
Satoshi Okada
Kentaro Takamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3D Matrix Ltd
Original Assignee
3D Matrix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47756984&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2653667(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 3D Matrix Ltd filed Critical 3D Matrix Ltd
Application granted granted Critical
Publication of ES2653667T3 publication Critical patent/ES2653667T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Un péptido para usar en la oclusión de escapes de aire del pulmón, caracterizado porque el péptido es un péptido anfifílico con una secuencia de aminoácidos Ac-(RADA)4-CONH2 (SEQ ID NO:1), que comprende residuos de aminoácidos con los aminoácidos hidrófilos y los aminoácidos hidrófobos unidos alternativamente, en donde el péptido es un péptido de autoensamblaje que muestra una estructura en lámina beta en solución acuosa en presencia de pH fisiológico y/o en presencia de un catión, y en donde el péptido se proporciona en una solución acuosa al 2.5 % (peso del péptido a volumen).

Description

imagen1
imagen2
imagen3
imagen4
imagen5
imagen6
imagen7
imagen8
imagen9
imagen10
imagen11
12
imagen12
imagen13
imagen14
imagen15
imagen16
17

Claims (1)

  1. imagen1
ES12828087.2T 2011-09-02 2012-08-31 Péptidos anfifílicos para la oclusión del escape de aire torácico Active ES2653667T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161530695P 2011-09-02 2011-09-02
US201161530695P 2011-09-02
PCT/IB2012/002172 WO2013030673A2 (en) 2011-09-02 2012-08-31 Amphiphilic peptides for thoracic air leakage occlusion

Publications (1)

Publication Number Publication Date
ES2653667T3 true ES2653667T3 (es) 2018-02-08

Family

ID=47756984

Family Applications (1)

Application Number Title Priority Date Filing Date
ES12828087.2T Active ES2653667T3 (es) 2011-09-02 2012-08-31 Péptidos anfifílicos para la oclusión del escape de aire torácico

Country Status (5)

Country Link
US (1) US20140329914A1 (es)
EP (1) EP2750687B1 (es)
JP (2) JP6034868B2 (es)
ES (1) ES2653667T3 (es)
WO (1) WO2013030673A2 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2011118341A (ru) 2008-10-06 2012-11-20 3-Д Матрикс, Лтд. (Jp) Агент для окклюзии тканей
US20150105336A1 (en) * 2012-03-09 2015-04-16 3-D Matrix, Ltd. Mucosa-elevating agent
WO2014008400A2 (en) 2012-07-06 2014-01-09 3-D Matrix, Inc. Fill-finish process for peptide solutions
SG11201506232VA (en) * 2013-03-06 2015-09-29 3D Matrix Ltd Surgical methods employing purified amphiphilic peptide compositions
EP3116522B1 (en) * 2014-03-10 2019-05-08 3-D Matrix Ltd. Autoassembling peptides for the treatment of pulmonary leakage
RU2016139369A (ru) * 2014-03-10 2018-04-10 3-Д Матрикс, Лтд. Композиции самоорганизующихся пептидов
JP6554121B2 (ja) * 2014-03-10 2019-07-31 株式会社スリー・ディー・マトリックス 気管支閉鎖剤としての自己組織化ペプチド
US10245299B2 (en) 2014-03-10 2019-04-02 3-D Matrix, Ltd. Autoassembling peptides for the treatment of pulmonary bulla
BR112016019510A2 (pt) 2014-03-10 2017-10-24 3 D Matrix Ltd esterilização e filtração de composições de peptídeos
US10814038B2 (en) 2016-01-06 2020-10-27 3-D Matrix, Ltd. Combination compositions
BR112018068941A2 (pt) 2016-03-18 2019-04-16 3-D Matrix, Ltd. prevenção de adesão de tecidos biológicos
US11174288B2 (en) 2016-12-06 2021-11-16 Northeastern University Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria
JP6973779B2 (ja) * 2017-07-07 2021-12-01 国立大学法人滋賀医科大学 肺手術時の空気漏れ検出用組成物
EP3818071A2 (en) 2018-07-03 2021-05-12 3-D Matrix, Ltd. Ionic self-assembling peptides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1879606T3 (da) * 2005-04-25 2013-09-23 Massachusetts Inst Technology Selvorganiserende peptider til fremme af hæmostase
WO2008073392A2 (en) * 2006-12-11 2008-06-19 3D Matrix, Inc. Compositions and methods for cardiac tissue protection and regeneration
JP5497451B2 (ja) * 2007-12-05 2014-05-21 株式会社スリー・ディー・マトリックス 創傷治癒・皮膚再建材
RU2011118341A (ru) * 2008-10-06 2012-11-20 3-Д Матрикс, Лтд. (Jp) Агент для окклюзии тканей

Also Published As

Publication number Publication date
JP6034868B2 (ja) 2016-11-30
JP2014527543A (ja) 2014-10-16
US20140329914A1 (en) 2014-11-06
EP2750687A2 (en) 2014-07-09
EP2750687A4 (en) 2015-03-18
WO2013030673A2 (en) 2013-03-07
WO2013030673A3 (en) 2013-10-31
EP2750687B1 (en) 2017-12-06
JP2017043604A (ja) 2017-03-02

Similar Documents

Publication Publication Date Title
ES2653667T3 (es) Péptidos anfifílicos para la oclusión del escape de aire torácico
ES2512141T3 (es) Análogo peptídico de oxintomodulina
ES2486675T3 (es) Análogo de péptido de oxintomodulina
ES2616658T3 (es) Péptidos que mimetizan el factor de crecimiento y sus usos
Nongonierma et al. The scientific evidence for the role of milk protein-derived bioactive peptides in humans: A Review
ES2606173T3 (es) Composición farmacéutica para el tratamiento y/o la prevención del cáncer
IN2014CN03098A (es)
Aoki et al. Peptide-based delivery to bone
ES2621809T3 (es) Inhibidores de TFPI y procedimientos de uso
CO6501168A2 (es) Inhibidor de la map cinasa p38
AR088392A1 (es) Macrociclos peptidomimeticos
WO2012137150A3 (en) Cell penetrating peptides for intracellular delivery of molecules
EP3363458A3 (en) A peptide
ES2488407T3 (es) Preparación farmacéutica que contiene lipasa de origen bacteriano
NZ593524A (en) A nonapeptide with anti-tumour activity
AR069220A1 (es) Procedimiento de obtencion de albumina humana de alta eficacia para su uso en terapia de detoxificacion
ES2525758T3 (es) Composición que comprende un péptido y un inhibidor de la neuraminidasa vírica
AR083126A1 (es) Composicion vacunal para el control de las infestaciones por ectoparasitos
ES2544954T3 (es) Péptidos multiméricos ramificados para diagnóstico y terapia de tumores
PE20150198A1 (es) Composicion farmaceutica para el tratamiento de la forma pulmonar de mal de montana por falta de oxigeno y presion de aire reducida
NZ756128A (en) Novel peptides and analogs for use in the treatment of oral mucositis
BR112012025044A2 (pt) método para conservar adjuvantes de alum e vacinas com adjuvantes de alum
MX2017015482A (es) Peptidos lipidados resistentes a proteasas.
TR201901259T4 (tr) Karaciğere özgü tanı için hidrofobik modifiye peptidler.
ES2496447T3 (es) Procedimiento de preparación de un aminoácido a partir de 2-aminobutirolactona