ES267046A1 - Un procedimiento para la preparaciën de la hidroxocobalamina - Google Patents
Un procedimiento para la preparaciën de la hidroxocobalaminaInfo
- Publication number
- ES267046A1 ES267046A1 ES0267046A ES267046A ES267046A1 ES 267046 A1 ES267046 A1 ES 267046A1 ES 0267046 A ES0267046 A ES 0267046A ES 267046 A ES267046 A ES 267046A ES 267046 A1 ES267046 A1 ES 267046A1
- Authority
- ES
- Spain
- Prior art keywords
- hydroxocobalamin
- added
- ferrous
- cyanocobalamin
- medium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YOZNUFWCRFCGIH-BYFNXCQMSA-L hydroxocobalamin Chemical compound O[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O YOZNUFWCRFCGIH-BYFNXCQMSA-L 0.000 title abstract 6
- 235000004867 hydroxocobalamin Nutrition 0.000 title abstract 3
- 239000011704 hydroxocobalamin Substances 0.000 title abstract 3
- 229960001103 hydroxocobalamin Drugs 0.000 title abstract 3
- RMRCNWBMXRMIRW-BYFNXCQMSA-M cyanocobalamin Chemical compound N#C[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O RMRCNWBMXRMIRW-BYFNXCQMSA-M 0.000 abstract 4
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 abstract 2
- 235000000639 cyanocobalamin Nutrition 0.000 abstract 2
- 239000011666 cyanocobalamin Substances 0.000 abstract 2
- 229960002104 cyanocobalamin Drugs 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 230000005587 bubbling Effects 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 229960002089 ferrous chloride Drugs 0.000 abstract 1
- 235000003891 ferrous sulphate Nutrition 0.000 abstract 1
- 239000011790 ferrous sulphate Substances 0.000 abstract 1
- 239000000706 filtrate Substances 0.000 abstract 1
- NMCUIPGRVMDVDB-UHFFFAOYSA-L iron dichloride Chemical compound Cl[Fe]Cl NMCUIPGRVMDVDB-UHFFFAOYSA-L 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MC229A MC309A1 (fr) | 1960-06-21 | 1960-06-21 | La transformation de la cyanocobalamine (b12) en hydroxocobalamine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES267046A1 true ES267046A1 (es) | 1961-11-01 |
Family
ID=19737423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0267046A Expired ES267046A1 (es) | 1960-06-21 | 1961-05-02 | Un procedimiento para la preparaciën de la hidroxocobalamina |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE604955A (fr) |
| CH (1) | CH397706A (fr) |
| ES (1) | ES267046A1 (fr) |
| GB (1) | GB918446A (fr) |
| MC (1) | MC309A1 (fr) |
-
1960
- 1960-06-21 MC MC229A patent/MC309A1/fr unknown
-
1961
- 1961-05-02 CH CH511161A patent/CH397706A/fr unknown
- 1961-05-02 ES ES0267046A patent/ES267046A1/es not_active Expired
- 1961-05-15 GB GB1767861A patent/GB918446A/en not_active Expired
- 1961-06-13 BE BE604955A patent/BE604955A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MC309A1 (fr) | 1962-03-21 |
| BE604955A (fr) | 1961-12-13 |
| CH397706A (fr) | 1965-08-31 |
| GB918446A (en) | 1963-02-13 |
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