ES2674361T3 - Combinación de un inhibidor de ALK y un inhibidor de CDK para el tratamiento de enfermedades celulares proliferativas - Google Patents
Combinación de un inhibidor de ALK y un inhibidor de CDK para el tratamiento de enfermedades celulares proliferativas Download PDFInfo
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- ES2674361T3 ES2674361T3 ES14766301.7T ES14766301T ES2674361T3 ES 2674361 T3 ES2674361 T3 ES 2674361T3 ES 14766301 T ES14766301 T ES 14766301T ES 2674361 T3 ES2674361 T3 ES 2674361T3
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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Landscapes
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| US201361871275P | 2013-08-28 | ||
| PCT/US2014/053244 WO2015031666A1 (en) | 2013-08-28 | 2014-08-28 | Combination of an alk inhibitor and a cdk inhibitor for the treatment of cell proliferative diseases |
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| ES2674361T3 true ES2674361T3 (es) | 2018-06-29 |
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| EP (1) | EP3038652B1 (2) |
| JP (1) | JP6479812B2 (2) |
| KR (1) | KR20160047521A (2) |
| CN (1) | CN106029099A (2) |
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| BR (1) | BR112016004358A8 (2) |
| CA (1) | CA2922684A1 (2) |
| ES (1) | ES2674361T3 (2) |
| MX (1) | MX2016002580A (2) |
| RU (1) | RU2016110874A (2) |
| WO (1) | WO2015031666A1 (2) |
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| KR101772134B1 (ko) | 2015-04-14 | 2017-08-29 | 한국화학연구원 | N2-(2-메톡시페닐)피리미딘 유도체, 이의 제조 방법 및 이를 유효 성분으로 함유하는 암의 예방 또는 치료용 약학적 조성물 |
| US11208630B2 (en) * | 2015-12-24 | 2021-12-28 | University Of Florida Research Foundation, Incorporated | AAV production using suspension adapted cells |
| US11395821B2 (en) | 2017-01-30 | 2022-07-26 | G1 Therapeutics, Inc. | Treatment of EGFR-driven cancer with fewer side effects |
| MX2020007312A (es) | 2018-01-08 | 2021-01-08 | G1 Therapeutics Inc | Regimenes de dosificacion superior de g1t38. |
| US20220143049A1 (en) | 2019-03-21 | 2022-05-12 | Onxeo | A dbait molecule in combination with kinase inhibitor for the treatment of cancer |
| EP3947368B1 (en) * | 2019-04-04 | 2025-09-03 | Dana-Farber Cancer Institute, Inc. | Bifunctional compounds comprising a cdk2/5 ligand, a linker and a e3 ubiquitin ligase binding degron for the treatment of cancer |
| EP4054579A1 (en) | 2019-11-08 | 2022-09-14 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Methods for the treatment of cancers that have acquired resistance to kinase inhibitors |
| EP4062938A4 (en) | 2019-11-18 | 2023-11-29 | Chugai Seiyaku Kabushiki Kaisha | COMBINATION MEDICINAL PRODUCTS |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| TW202146017A (zh) | 2020-03-05 | 2021-12-16 | 美商輝瑞股份有限公司 | 間變性淋巴瘤激酶抑制劑及周期蛋白依賴型激酶抑制劑之組合 |
| US20230381176A1 (en) * | 2020-09-25 | 2023-11-30 | Ascentage Pharma (Suzhou) Co., Ltd. | A pharmaceutical composition and use thereof for treatment of cancer |
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- 2014-08-28 CA CA2922684A patent/CA2922684A1/en not_active Abandoned
- 2014-08-28 CN CN201480059490.0A patent/CN106029099A/zh active Pending
- 2014-08-28 RU RU2016110874A patent/RU2016110874A/ru not_active Application Discontinuation
-
2017
- 2017-08-25 AU AU2017219093A patent/AU2017219093A1/en not_active Abandoned
-
2018
- 2018-07-16 US US16/035,774 patent/US20180318305A1/en not_active Abandoned
- 2018-09-27 AU AU2018236813A patent/AU2018236813A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP3038652B1 (en) | 2018-03-21 |
| RU2016110874A (ru) | 2017-10-04 |
| WO2015031666A1 (en) | 2015-03-05 |
| AU2014312261A1 (en) | 2016-03-10 |
| MX2016002580A (es) | 2016-10-26 |
| JP2016529285A (ja) | 2016-09-23 |
| RU2016110874A3 (2) | 2018-06-27 |
| EP3038652A1 (en) | 2016-07-06 |
| AU2018236813A1 (en) | 2018-10-18 |
| US20180318305A1 (en) | 2018-11-08 |
| KR20160047521A (ko) | 2016-05-02 |
| US20160361314A1 (en) | 2016-12-15 |
| JP6479812B2 (ja) | 2019-03-06 |
| AU2017219093A1 (en) | 2017-09-14 |
| BR112016004358A8 (pt) | 2020-02-11 |
| CA2922684A1 (en) | 2015-03-05 |
| CN106029099A (zh) | 2016-10-12 |
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