ES2684856B1 - Metodo para producir una matriz de tejido descelularizado - Google Patents

Metodo para producir una matriz de tejido descelularizado Download PDF

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Publication number
ES2684856B1
ES2684856B1 ES201890038A ES201890038A ES2684856B1 ES 2684856 B1 ES2684856 B1 ES 2684856B1 ES 201890038 A ES201890038 A ES 201890038A ES 201890038 A ES201890038 A ES 201890038A ES 2684856 B1 ES2684856 B1 ES 2684856B1
Authority
ES
Spain
Prior art keywords
decelularized
producing
fabric matrix
fabric
matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES201890038A
Other languages
English (en)
Other versions
ES2684856A2 (es
ES2684856R1 (es
Inventor
Pardo Iratxe Madarieta
Urquia Nerea Garcia
Garcia Rubén Fernandez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fundacion Tecnalia Research and Innovation
Original Assignee
Fundacion Tecnalia Research and Innovation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fundacion Tecnalia Research and Innovation filed Critical Fundacion Tecnalia Research and Innovation
Publication of ES2684856A2 publication Critical patent/ES2684856A2/es
Publication of ES2684856R1 publication Critical patent/ES2684856R1/es
Application granted granted Critical
Publication of ES2684856B1 publication Critical patent/ES2684856B1/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
ES201890038A 2015-12-30 2016-12-29 Metodo para producir una matriz de tejido descelularizado Active ES2684856B1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15203113 2015-12-30
EP15203113 2015-12-30
PCT/EP2016/082849 WO2017114902A1 (en) 2015-12-30 2016-12-29 Method for producing a decellularized tissue matrix

Publications (3)

Publication Number Publication Date
ES2684856A2 ES2684856A2 (es) 2018-10-04
ES2684856R1 ES2684856R1 (es) 2018-10-09
ES2684856B1 true ES2684856B1 (es) 2019-07-31

Family

ID=55168107

Family Applications (1)

Application Number Title Priority Date Filing Date
ES201890038A Active ES2684856B1 (es) 2015-12-30 2016-12-29 Metodo para producir una matriz de tejido descelularizado

Country Status (2)

Country Link
ES (1) ES2684856B1 (es)
WO (1) WO2017114902A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108079375B (zh) * 2018-02-08 2021-01-15 北京桀亚莱福生物技术有限责任公司 一种内置生物套及其制备方法与应用
CN118846235A (zh) * 2019-12-30 2024-10-29 广东泓志生物科技有限公司 大网膜脱细胞基质材料的制备方法及软骨组织的构建方法
CN114796614B (zh) * 2021-09-13 2024-02-06 暨南大学 一种人脂肪组织脱细胞外基质及其制备与应用
WO2024206945A2 (en) * 2023-03-31 2024-10-03 Sinuse Corp. Allogeneic and xenogeneic subcutaneous adipose tissue and methods for preserving same
EP4704933A1 (en) 2023-05-03 2026-03-11 Volumina Medical SA Devices and methods for preparing and conditioning biological assemblies for minimally invasive delivery for tissue engineering, cell therapies and other therapeutic applications
CN116850347B (zh) * 2023-09-01 2025-01-07 北京药有为医药科技有限公司 一种可注射型脂肪脱细胞外基质复合材料的水凝胶
CN118370871B (zh) * 2024-06-24 2024-09-06 北京帝康医药投资管理有限公司 一种脱细胞生物网膜制备方法及由其制得的脱细胞生物网膜
CN118641745B (zh) * 2024-08-13 2024-10-22 浙江大学 一种基于厚切技术的全组织三维结构脱细胞基质制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996032905A1 (en) * 1995-04-19 1996-10-24 St. Jude Medical, Inc. Matrix substrate for a viable body tissue-derived prosthesis and method for making the same

Also Published As

Publication number Publication date
ES2684856A2 (es) 2018-10-04
WO2017114902A1 (en) 2017-07-06
ES2684856R1 (es) 2018-10-09

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