ES2926480T3 - Dispositivos y sistemas retentivos para la liberación in situ de principios activos farmacéuticos - Google Patents
Dispositivos y sistemas retentivos para la liberación in situ de principios activos farmacéuticos Download PDFInfo
- Publication number
- ES2926480T3 ES2926480T3 ES14824124T ES14824124T ES2926480T3 ES 2926480 T3 ES2926480 T3 ES 2926480T3 ES 14824124 T ES14824124 T ES 14824124T ES 14824124 T ES14824124 T ES 14824124T ES 2926480 T3 ES2926480 T3 ES 2926480T3
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- film
- compartment
- stomach
- gastric retention
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- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 229960003107 tramadol hydrochloride Drugs 0.000 description 1
- 235000013337 tricalcium citrate Nutrition 0.000 description 1
- WEAPVABOECTMGR-UHFFFAOYSA-N triethyl 2-acetyloxypropane-1,2,3-tricarboxylate Chemical compound CCOC(=O)CC(C(=O)OCC)(OC(C)=O)CC(=O)OCC WEAPVABOECTMGR-UHFFFAOYSA-N 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
- 210000002438 upper gastrointestinal tract Anatomy 0.000 description 1
- 229960004688 venlafaxine Drugs 0.000 description 1
- PNVNVHUZROJLTJ-UHFFFAOYSA-N venlafaxine Chemical compound C1=CC(OC)=CC=C1C(CN(C)C)C1(O)CCCCC1 PNVNVHUZROJLTJ-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/10—Trunk
- A61M2210/1042—Alimentary tract
- A61M2210/1053—Stomach
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US201361912204P | 2013-12-05 | 2013-12-05 | |
| PCT/IL2014/051063 WO2015083171A1 (fr) | 2013-12-05 | 2014-12-04 | Dispositifs et systèmes de rétention pour la libération in-situ d'agents pharmaceutiques actifs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2926480T3 true ES2926480T3 (es) | 2022-10-26 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| ES14824124T Active ES2926480T3 (es) | 2013-12-05 | 2014-12-04 | Dispositivos y sistemas retentivos para la liberación in situ de principios activos farmacéuticos |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11129793B2 (fr) |
| EP (1) | EP3091962B1 (fr) |
| JP (3) | JP2017502935A (fr) |
| CN (2) | CN105899198A (fr) |
| AU (1) | AU2014358675B2 (fr) |
| BR (1) | BR112016012615B1 (fr) |
| CA (1) | CA2932574C (fr) |
| ES (1) | ES2926480T3 (fr) |
| IL (1) | IL245987B (fr) |
| WO (1) | WO2015083171A1 (fr) |
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| WO2013183058A2 (fr) | 2012-06-07 | 2013-12-12 | Tulip Medical Ltd. | Dispositif étendu |
| EP3091962B1 (fr) * | 2013-12-05 | 2022-06-08 | Epitomee Medical Ltd. | Dispositifs et systèmes de rétention pour la libération in-situ d'agents pharmaceutiques actifs |
| US20170266112A1 (en) | 2014-06-11 | 2017-09-21 | Massachusetts Institute Of Technology | Residence structures and related methods |
| NZ727659A (en) | 2014-06-11 | 2021-12-24 | Massachusetts Inst Technology | Residence structures and related methods |
| US11576859B2 (en) | 2015-10-23 | 2023-02-14 | Lyndra Therapeutics, Inc. | Gastric residence systems for sustained release of therapeutic agents and methods of use thereof |
| WO2017100367A1 (fr) | 2015-12-08 | 2017-06-15 | Lyndra, Inc. | Configurations géométriques de systèmes à résidence gastrique |
| CN109310639A (zh) | 2016-05-27 | 2019-02-05 | 林德拉有限公司 | 用于胃驻留系统的材料结构 |
| JP2019532947A (ja) | 2016-09-30 | 2019-11-14 | リンドラ,インコーポレイティド | アダマンタン系薬物の持続的送達のための胃内滞留システム |
| CN110035718B (zh) | 2016-12-02 | 2021-04-06 | 克雷西奥生物科技有限公司 | 胃内滞留系统 |
| CA3066658A1 (fr) | 2017-06-09 | 2018-12-13 | Lyndra, Inc. | Systemes gastriques a demeure avec films modulant le taux de liberation |
| US11793751B2 (en) * | 2017-09-20 | 2023-10-24 | Lyndra Therapeutics, Inc. | Encapsulation of gastric residence systems |
| WO2019111132A1 (fr) | 2017-12-04 | 2019-06-13 | Clexio Biosciences Ltd. | Système de résidence gastrique à action prolongée |
| CN108721246B (zh) * | 2018-05-29 | 2021-06-25 | 王喆明 | 高分子材料构建的多单元超长效口服制剂及其制备方法 |
| WO2020102629A1 (fr) * | 2018-11-15 | 2020-05-22 | Massachusetts Institute Of Technology | Dispositifs à demeure à commande thermique |
| US11389398B2 (en) | 2019-05-14 | 2022-07-19 | Clexio Biosciences Ltd. | Gastroretentive treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease |
| US12544310B2 (en) | 2020-03-02 | 2026-02-10 | Craft Health Pte Ltd. | Method of manufacturing oral dosage forms for extended drug release |
| CA3200821A1 (fr) | 2020-12-07 | 2022-06-16 | Gil Cohen | Dispositifs expansibles intragastriques |
| KR20230170674A (ko) * | 2021-03-15 | 2023-12-19 | 이피토미 메디칼 엘티디 | 활성제를 조직으로 전달하기 위한 확장가능한 디바이스 |
| WO2022195476A1 (fr) | 2021-03-15 | 2022-09-22 | Clexio Biosciences Ltd. | Dispositifs de rétention gastrique pour l'évaluation d'états intragastriques |
| JP2024531127A (ja) * | 2021-08-09 | 2024-08-29 | マサチューセッツ インスティテュート オブ テクノロジー | 摂取可能デバイス |
| AU2023346631A1 (en) * | 2022-09-21 | 2025-05-01 | Epitomee Medical Ltd. | Controllably disintegrable self-expandable ingestible devices |
| EP4604932A1 (fr) * | 2022-10-18 | 2025-08-27 | Triastek, Inc. | Formes galéniques orales de medicaments pour rétention dans l'estomac |
| CN116077417B (zh) * | 2022-12-29 | 2024-03-22 | 汤臣倍健股份有限公司 | 一种胃滞留片剂及制备方法 |
| CN117800668A (zh) * | 2023-11-14 | 2024-04-02 | 苏州上建杭鑫混凝土有限公司 | 一种地下高抗渗耐久性混凝土 |
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-
2014
- 2014-12-04 EP EP14824124.3A patent/EP3091962B1/fr active Active
- 2014-12-04 CN CN201480072619.1A patent/CN105899198A/zh active Pending
- 2014-12-04 CA CA2932574A patent/CA2932574C/fr active Active
- 2014-12-04 BR BR112016012615-7A patent/BR112016012615B1/pt active IP Right Grant
- 2014-12-04 AU AU2014358675A patent/AU2014358675B2/en active Active
- 2014-12-04 CN CN202210337069.8A patent/CN114668960A/zh active Pending
- 2014-12-04 ES ES14824124T patent/ES2926480T3/es active Active
- 2014-12-04 US US15/101,045 patent/US11129793B2/en active Active
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- 2014-12-04 JP JP2016536242A patent/JP2017502935A/ja active Pending
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| Publication number | Publication date |
|---|---|
| AU2014358675B2 (en) | 2019-10-03 |
| BR112016012615A2 (pt) | 2017-08-08 |
| US20180250226A1 (en) | 2018-09-06 |
| JP2021193122A (ja) | 2021-12-23 |
| BR112016012615A8 (pt) | 2023-01-03 |
| IL245987B (en) | 2020-04-30 |
| IL245987A0 (en) | 2016-07-31 |
| JP7291025B2 (ja) | 2023-06-14 |
| CA2932574A1 (fr) | 2015-06-11 |
| AU2014358675A1 (en) | 2016-06-16 |
| CN105899198A (zh) | 2016-08-24 |
| EP3091962A1 (fr) | 2016-11-16 |
| CN114668960A (zh) | 2022-06-28 |
| CA2932574C (fr) | 2023-03-07 |
| BR112016012615B1 (pt) | 2023-02-07 |
| JP2017502935A (ja) | 2017-01-26 |
| US11129793B2 (en) | 2021-09-28 |
| EP3091962B1 (fr) | 2022-06-08 |
| WO2015083171A1 (fr) | 2015-06-11 |
| JP2019196396A (ja) | 2019-11-14 |
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