ES2926480T3 - Dispositivos y sistemas retentivos para la liberación in situ de principios activos farmacéuticos - Google Patents

Dispositivos y sistemas retentivos para la liberación in situ de principios activos farmacéuticos Download PDF

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Publication number
ES2926480T3
ES2926480T3 ES14824124T ES14824124T ES2926480T3 ES 2926480 T3 ES2926480 T3 ES 2926480T3 ES 14824124 T ES14824124 T ES 14824124T ES 14824124 T ES14824124 T ES 14824124T ES 2926480 T3 ES2926480 T3 ES 2926480T3
Authority
ES
Spain
Prior art keywords
film
compartment
stomach
gastric retention
active ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES14824124T
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English (en)
Spanish (es)
Inventor
Nir Betser
Valery Artmanov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Epitomee Medical Ltd
Original Assignee
Epitomee Medical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epitomee Medical Ltd filed Critical Epitomee Medical Ltd
Application granted granted Critical
Publication of ES2926480T3 publication Critical patent/ES2926480T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/10Trunk
    • A61M2210/1042Alimentary tract
    • A61M2210/1053Stomach

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
ES14824124T 2013-12-05 2014-12-04 Dispositivos y sistemas retentivos para la liberación in situ de principios activos farmacéuticos Active ES2926480T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361912204P 2013-12-05 2013-12-05
PCT/IL2014/051063 WO2015083171A1 (fr) 2013-12-05 2014-12-04 Dispositifs et systèmes de rétention pour la libération in-situ d'agents pharmaceutiques actifs

Publications (1)

Publication Number Publication Date
ES2926480T3 true ES2926480T3 (es) 2022-10-26

Family

ID=52282802

Family Applications (1)

Application Number Title Priority Date Filing Date
ES14824124T Active ES2926480T3 (es) 2013-12-05 2014-12-04 Dispositivos y sistemas retentivos para la liberación in situ de principios activos farmacéuticos

Country Status (10)

Country Link
US (1) US11129793B2 (fr)
EP (1) EP3091962B1 (fr)
JP (3) JP2017502935A (fr)
CN (2) CN105899198A (fr)
AU (1) AU2014358675B2 (fr)
BR (1) BR112016012615B1 (fr)
CA (1) CA2932574C (fr)
ES (1) ES2926480T3 (fr)
IL (1) IL245987B (fr)
WO (1) WO2015083171A1 (fr)

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WO2013183058A2 (fr) 2012-06-07 2013-12-12 Tulip Medical Ltd. Dispositif étendu
EP3091962B1 (fr) * 2013-12-05 2022-06-08 Epitomee Medical Ltd. Dispositifs et systèmes de rétention pour la libération in-situ d'agents pharmaceutiques actifs
US20170266112A1 (en) 2014-06-11 2017-09-21 Massachusetts Institute Of Technology Residence structures and related methods
NZ727659A (en) 2014-06-11 2021-12-24 Massachusetts Inst Technology Residence structures and related methods
US11576859B2 (en) 2015-10-23 2023-02-14 Lyndra Therapeutics, Inc. Gastric residence systems for sustained release of therapeutic agents and methods of use thereof
WO2017100367A1 (fr) 2015-12-08 2017-06-15 Lyndra, Inc. Configurations géométriques de systèmes à résidence gastrique
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JP2019532947A (ja) 2016-09-30 2019-11-14 リンドラ,インコーポレイティド アダマンタン系薬物の持続的送達のための胃内滞留システム
CN110035718B (zh) 2016-12-02 2021-04-06 克雷西奥生物科技有限公司 胃内滞留系统
CA3066658A1 (fr) 2017-06-09 2018-12-13 Lyndra, Inc. Systemes gastriques a demeure avec films modulant le taux de liberation
US11793751B2 (en) * 2017-09-20 2023-10-24 Lyndra Therapeutics, Inc. Encapsulation of gastric residence systems
WO2019111132A1 (fr) 2017-12-04 2019-06-13 Clexio Biosciences Ltd. Système de résidence gastrique à action prolongée
CN108721246B (zh) * 2018-05-29 2021-06-25 王喆明 高分子材料构建的多单元超长效口服制剂及其制备方法
WO2020102629A1 (fr) * 2018-11-15 2020-05-22 Massachusetts Institute Of Technology Dispositifs à demeure à commande thermique
US11389398B2 (en) 2019-05-14 2022-07-19 Clexio Biosciences Ltd. Gastroretentive treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease
US12544310B2 (en) 2020-03-02 2026-02-10 Craft Health Pte Ltd. Method of manufacturing oral dosage forms for extended drug release
CA3200821A1 (fr) 2020-12-07 2022-06-16 Gil Cohen Dispositifs expansibles intragastriques
KR20230170674A (ko) * 2021-03-15 2023-12-19 이피토미 메디칼 엘티디 활성제를 조직으로 전달하기 위한 확장가능한 디바이스
WO2022195476A1 (fr) 2021-03-15 2022-09-22 Clexio Biosciences Ltd. Dispositifs de rétention gastrique pour l'évaluation d'états intragastriques
JP2024531127A (ja) * 2021-08-09 2024-08-29 マサチューセッツ インスティテュート オブ テクノロジー 摂取可能デバイス
AU2023346631A1 (en) * 2022-09-21 2025-05-01 Epitomee Medical Ltd. Controllably disintegrable self-expandable ingestible devices
EP4604932A1 (fr) * 2022-10-18 2025-08-27 Triastek, Inc. Formes galéniques orales de medicaments pour rétention dans l'estomac
CN116077417B (zh) * 2022-12-29 2024-03-22 汤臣倍健股份有限公司 一种胃滞留片剂及制备方法
CN117800668A (zh) * 2023-11-14 2024-04-02 苏州上建杭鑫混凝土有限公司 一种地下高抗渗耐久性混凝土

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BR112016012615A2 (pt) 2017-08-08
US20180250226A1 (en) 2018-09-06
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BR112016012615A8 (pt) 2023-01-03
IL245987B (en) 2020-04-30
IL245987A0 (en) 2016-07-31
JP7291025B2 (ja) 2023-06-14
CA2932574A1 (fr) 2015-06-11
AU2014358675A1 (en) 2016-06-16
CN105899198A (zh) 2016-08-24
EP3091962A1 (fr) 2016-11-16
CN114668960A (zh) 2022-06-28
CA2932574C (fr) 2023-03-07
BR112016012615B1 (pt) 2023-02-07
JP2017502935A (ja) 2017-01-26
US11129793B2 (en) 2021-09-28
EP3091962B1 (fr) 2022-06-08
WO2015083171A1 (fr) 2015-06-11
JP2019196396A (ja) 2019-11-14

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