ES293280A1 - Procedimiento de preparación de derivados 1-hidroximetil desacetilamino colchícicos - Google Patents

Procedimiento de preparación de derivados 1-hidroximetil desacetilamino colchícicos

Info

Publication number: ES293280A1
Authority: ES; Spain
Prior art keywords: carbon atoms; radical; acid; derivative; hydroxymethyl
Prior art date: 1962-11-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES293280A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sanofi Aventis France

Original Assignee

Roussel Uclaf SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1962-11-09

Filing date

1963-11-07

Publication date

1964-01-01

1962-11-09 Priority claimed from FR914928A external-priority patent/FR1359642A/fr

1963-11-07 Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA

1964-01-01 Publication of ES293280A1 publication Critical patent/ES293280A1/es

Status Expired legal-status Critical Current

Links

-1 1-hydroxymethyl Chemical group 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 5
IAKHMKGGTNLKSZ-INIZCTEOSA-N (S)-colchicine Chemical compound C1([C@@H](NC(C)=O)CC2)=CC(=O)C(OC)=CC=C1C1=C2C=C(OC)C(OC)=C1OC IAKHMKGGTNLKSZ-INIZCTEOSA-N 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 2
150000002148 esters Chemical class 0.000 abstract 2
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
229910021627 Tin(IV) chloride Inorganic materials 0.000 abstract 1
230000002378 acidificating effect Effects 0.000 abstract 1
150000008064 anhydrides Chemical class 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 abstract 1
150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
239000003054 catalyst Substances 0.000 abstract 1
239000003638 chemical reducing agent Substances 0.000 abstract 1
AOGYCOYQMAVAFD-UHFFFAOYSA-N chlorocarbonic acid Chemical compound OC(Cl)=O AOGYCOYQMAVAFD-UHFFFAOYSA-N 0.000 abstract 1
229960001338 colchicine Drugs 0.000 abstract 1
125000004122 cyclic group Chemical group 0.000 abstract 1
230000032050 esterification Effects 0.000 abstract 1
238000005886 esterification reaction Methods 0.000 abstract 1
238000006266 etherification reaction Methods 0.000 abstract 1
150000002170 ethers Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
HPGGPRDJHPYFRM-UHFFFAOYSA-J tin(iv) chloride Chemical compound Cl[Sn](Cl)(Cl)Cl HPGGPRDJHPYFRM-UHFFFAOYSA-J 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
- C07D311/44—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3
- C07D311/46—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3 unsubstituted in the carbocyclic ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ES293280A 1962-11-09 1963-11-07 Procedimiento de preparación de derivados 1-hidroximetil desacetilamino colchícicos Expired ES293280A1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR914928A FR1359642A (fr)	1962-10-11	1962-11-09	Dérivés colchiciniques et procédé de préparation
FR919491A FR1359662A (fr)	1962-10-11	1962-12-21	Dérivés colchiciques et procédé de préparation

Publications (1)

Publication Number	Publication Date
ES293280A1 true ES293280A1 (es)	1964-01-01

Family

ID=26198328

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES293280A Expired ES293280A1 (es)	1962-11-09	1963-11-07	Procedimiento de preparación de derivados 1-hidroximetil desacetilamino colchícicos

Country Status (3)

Country	Link
BE (1)	BE639707A (es)
DK (3)	DK108092C (es)
ES (1)	ES293280A1 (es)

1963
- 1963-10-31 DK DK551564AA patent/DK108092C/da active
- 1963-10-31 DK DK512963AA patent/DK106856C/da active
- 1963-10-31 DK DK551664AA patent/DK105766C/da active
- 1963-11-07 ES ES293280A patent/ES293280A1/es not_active Expired
- 1963-11-08 BE BE639707A patent/BE639707A/fr unknown

Also Published As

Publication number	Publication date
DK105766C (da)	1966-11-07
DK106856C (da)	1967-03-28
BE639707A (fr)	1964-05-08
DK108092C (da)	1967-08-28

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