ES2965754T3 - 2-Iminobiotina para uso en el tratamiento de lesiones de células cerebrales - Google Patents

2-Iminobiotina para uso en el tratamiento de lesiones de células cerebrales Download PDF

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Publication number
ES2965754T3
ES2965754T3 ES16825913T ES16825913T ES2965754T3 ES 2965754 T3 ES2965754 T3 ES 2965754T3 ES 16825913 T ES16825913 T ES 16825913T ES 16825913 T ES16825913 T ES 16825913T ES 2965754 T3 ES2965754 T3 ES 2965754T3
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ES
Spain
Prior art keywords
iminobiotin
individual
day
administered
dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES16825913T
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English (en)
Spanish (es)
Inventor
Paul Willem Theresia Josef Leufkens
Cacha Marie Pétronelle Cathérine Dorothée Peeters
Huibert Alexander Tjabbes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neurophyxia BV
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Neurophyxia BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Neurophyxia BV filed Critical Neurophyxia BV
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Publication of ES2965754T3 publication Critical patent/ES2965754T3/es
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41881,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES16825913T 2015-12-16 2016-12-16 2-Iminobiotina para uso en el tratamiento de lesiones de células cerebrales Active ES2965754T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15200492 2015-12-16
PCT/NL2016/050880 WO2017105237A1 (en) 2015-12-16 2016-12-16 2-iminobiotin for use in the treatment of brain cell injury

Publications (1)

Publication Number Publication Date
ES2965754T3 true ES2965754T3 (es) 2024-04-16

Family

ID=54936830

Family Applications (1)

Application Number Title Priority Date Filing Date
ES16825913T Active ES2965754T3 (es) 2015-12-16 2016-12-16 2-Iminobiotina para uso en el tratamiento de lesiones de células cerebrales

Country Status (11)

Country Link
US (3) US10525039B2 (pl)
EP (1) EP3389653B1 (pl)
JP (1) JP6975165B2 (pl)
AU (1) AU2016372396B2 (pl)
CA (1) CA3008790A1 (pl)
DK (1) DK3389653T3 (pl)
ES (1) ES2965754T3 (pl)
FI (1) FI3389653T3 (pl)
PL (1) PL3389653T3 (pl)
PT (1) PT3389653T (pl)
WO (1) WO2017105237A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3389653T (pt) * 2015-12-16 2023-12-28 Neurophyxia B V 2-iminobiotina para utilização no tratamento de lesão celular cerebral
EP3749091A4 (en) * 2018-02-09 2022-01-12 Yale University Methods, systems and compositions for normothermic ex vivo restoration and preservation of intact organs
MX2023011285A (es) * 2021-03-23 2023-11-22 Neurophyxia B V 2-iminobiotina para uso en el tratamiento de accidente cerebrovascular.
WO2022203505A1 (en) * 2021-03-23 2022-09-29 Neurophyxia B.V. 2-iminobiotin for use in the treatment of stroke

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2359646C (en) 1999-01-21 2008-12-02 Bristol-Myers Squibb Company Complex of ras-farnesyltransferase inhibitor and sulfobutylether-7-.beta.-cyclodextrin or 2-hydroxypropyl-.beta.-cyclodextrin and method
US7087633B2 (en) * 2000-03-31 2006-08-08 Universitair Medisch Centrum Method for treating perinatal asphyxia in a human or animal neonate
AU777022B2 (en) 2000-03-31 2004-09-30 Neurophyxia B.V. Composition for the prevention and/or treatment, in newborn babies, of the effects of complications during childbirth
US7319090B2 (en) 2002-11-27 2008-01-15 University Of North Carolina At Chapel Hill Methods of treating cerebral ischemia
WO2008040360A2 (en) 2006-10-04 2008-04-10 Neurokey A/S Use of hypothermia inducing drugs to treat ischemia
CN103037904B (zh) 2010-05-26 2015-04-22 纽柔菲克西亚有限公司 2-亚氨基生物素制剂及其应用
SG11201407326XA (en) * 2012-05-23 2014-12-30 Cellix Bio Private Ltd Compositions and methods for treatment of mucositis
GB2504263B (en) * 2012-06-08 2015-09-16 Gw Pharma Ltd Synergistic therapies for neuroprotection
US10092591B2 (en) 2014-02-27 2018-10-09 University Of Alaska Fairbanks Methods and compositions for the treatment of ischemic injury to tissue using therapeutic hypothermia
PT3389653T (pt) 2015-12-16 2023-12-28 Neurophyxia B V 2-iminobiotina para utilização no tratamento de lesão celular cerebral

Also Published As

Publication number Publication date
US11426387B2 (en) 2022-08-30
EP3389653B1 (en) 2023-11-08
AU2016372396B2 (en) 2022-04-14
DK3389653T3 (da) 2024-01-02
US20200147049A1 (en) 2020-05-14
WO2017105237A1 (en) 2017-06-22
AU2016372396A1 (en) 2018-06-28
FI3389653T3 (fi) 2023-12-18
CA3008790A1 (en) 2017-06-22
US10722496B2 (en) 2020-07-28
PT3389653T (pt) 2023-12-28
US10525039B2 (en) 2020-01-07
EP3389653A1 (en) 2018-10-24
JP2019501969A (ja) 2019-01-24
US20190262316A1 (en) 2019-08-29
US20200338046A1 (en) 2020-10-29
PL3389653T3 (pl) 2024-02-26
JP6975165B2 (ja) 2021-12-01

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