ES2969795T3 - A disinfectant and cleaning composition - Google Patents

Abstract

The present invention relates to a composition comprising: 0.5% to 4% by weight of hydrogen peroxide; from 0.1% to 0.5% by weight of an organic phosphonic acid; from 0.25% to 0.8% by weight of lactic acid; and that has a pH of 2 to 3.6 and processes for its preparation. It also refers to its use as a disinfectant and cleaner and to a method of disinfection and/or cleaning by applying it to a surface. (Automatic translation with Google Translate, without legal value)

Description

DESCRIPTION

A disinfectant and cleaning composition

The present application claims the benefit of European Patent Application EP20382501.3 filed on June 10, 2020.

The present invention relates to the field of disinfection. In particular, it refers to a stable, non-toxic and non-corrosive composition containing hydrogen peroxide, effective for use as a disinfectant and cleaning composition. It also relates to processes for its preparation and a method for its use.

Background of the technique

Hydrogen peroxide solutions have been used for many years for various purposes, including whitening, disinfecting and cleaning a variety of surfaces ranging from skin, hair, mucous membranes to contact lenses, instruments, household and industrial surfaces.

In particular, hydrogen peroxide compositions are especially attractive because hydrogen peroxide exhibits broad-spectrum antimicrobial activity and because it decomposes into harmless products (i.e., water and oxygen). Broad-spectrum antimicrobial activity is important in situations where harmful organisms are present, but their identity is unknown. Likewise, apart from the disinfectant activity of hydrogen peroxide, it is also a reference product due to its versatile effect as a cleaner that helps eliminate limescale, calcium stains and yellow stains.

Unfortunately, using hydrogen peroxide also has some drawbacks. One of the most significant problems with hydrogen peroxide compositions is the inherent instability of hydrogen peroxide solutions and the time required for hydrogen peroxide to disinfect a surface to which it has been applied. In fact, unless strict conditions are met, hydrogen peroxide solutions begin to decompose into oxygen gas and water in an extremely short time. Typical hydrogen peroxide solutions used for the purposes mentioned above are in the range of about 0.5% to about 10% by weight of hydrogen peroxide in water. The rate at which such dilute hydrogen peroxide solutions decompose will, of course, depend on some factors such as pH and the presence of trace amounts of various metallic impurities (such as copper or chromium), which may act as a catalyst. to decompose it. Furthermore, at moderately elevated temperatures, the rate of decomposition of such dilute aqueous hydrogen peroxide solutions is greatly accelerated. Therefore, a common difficulty in formulating such a hydrogen peroxide composition is ensuring that it remains stable during storage but is sufficiently active during use, which is particularly difficult to achieve in liquid compositions.

One solution has been to stabilize hydrogen peroxide by adding stabilizing agents. Typically, these stabilizing agents are chelators or sequestering agents that are added to hydrogen peroxide solutions to combat decomposition due to the presence of traces of impurities (mainly dissolved metals). Many types of compounds have been used to fulfill this function, such as diols; quinones; stannate salts; pyrophosphates; phenolsulfate; sodium stannate; N,N-lower alkylaniline; sulfamic acid; sulfolane; and straight chain di-alkylsulfones and lower sulfoxides; phosphonic acids and their salts; different aromatic compounds and salts of aminocarboxylic acids; acrylic acid polymers; polyphosphates; polyaminopolyphosphonic acids and/or their salts. However, many of the compounds suggested above have several problems and challenges associated with them, such as toxicity, environmental impact and poor performance. Aside from concerns about toxicity and environmental impact, many of these require specific conditions to provide adequate hydrogen peroxide stability, such as specific pH levels or relatively low concentrations of hydrogen peroxide. It is known in the state of the art that the control of the pH of the hydrogen peroxide composition is approximately 2.5 and 5.5, as well as the use of low hydrogen peroxide is appropriate for having a stable composition but not They provide enough disinfecting, cleaning and/or whitening power to be useful for numerous home and professional situations. Other disadvantages of using hydrogen peroxide are related to its high toxicity and corrosive properties that cause serious health and safety risks. In particular, at high concentrations in laboratory or industrial environments, hydrogen peroxide is a strong oxidant and can be corrosive to the eyes, skin and respiratory system, causing skin burns and tissue damage. In fact, they are associated with job security. At lower concentrations such as "household grade" concentrations, hydrogen peroxide is generally considered safe to use, but should never be inhaled and/or ingested. In fact, even at low concentrations, hydrogen peroxide should be handled and stored carefully, whether at home or in the workplace.

Likewise, hydrogen peroxide is known to be highly corrosive and has significant material incompatibility problems. In particular, hydrogen peroxide can damage both metal surfaces such as metal pipes and instruments and surfaces of organic materials such as carbonate-based surfaces (such as marble), which is undesirable. However, in most cases, the reduction of the undesirable corrosive effect of hydrogen peroxide solutions is achieved by reducing the amount of active ingredients or increasing the pH values, compromising their disinfectant and/or cleaning activity. In particular, when the cleaning activity is especially critical involving the removal of limescale, calcium stains, yellow stains, as well as the removal of soap (scum, soap scum and stains) and grease, the addition of active ingredients is required. that have one or more of the activities mentioned above. However, the introduction of more components, and particularly active ingredients, can make the preparation of compositions difficult since certain components can affect the stability and/or activity of other components of the composition. Document WO 2006/097666 A1 refers to a cleaning and/or disinfectant composition for hard surfaces that comprises an acid constituent; anionic surfactant; suspended inclusions that appear as visibly discernible, discrete particulate materials; thickening constituent and an oxidizing constituent.

Therefore, from what is known in the art, it follows that there is still a need to provide safe, stable hydrogen peroxide disinfectant and cleaning compositions, without having material compatibility problems.

Summary of the invention

The inventors have provided a stable hydrogen peroxide composition that has an effective disinfectant activity and that achieves a very deep and at the same time broad cleaning effect.

In particular, the inventors have discovered that the use of a low amount of hydrogen peroxide (0.5% to 4%) and lactic acid (0.25% to 0.8%) together with an amount of organic acid 0.1% to 0.5% phosphonic acid makes it possible to provide a stable composition to be stored without decomposition of hydrogen peroxide; and have at the same time the appropriate pH and concentration of active ingredients to provide a double effective disinfectant and cleaning effect. These effects are carried out without causing corrosion and/or damage to the surface that has been treated. And, furthermore, without causing inhalation problems and skin damage to the person who applies the composition to the surface that has been treated.

As indicated above, in this type of composition there are interactions between the components that can affect its activity and/or the stability of the composition. Specifically, organic phosphonic acid is known to effectively stabilize hydrogen peroxide. However, the inventors have surprisingly discovered that the organic phosphonic acid has a negative effect on the lactic acid present in the composition, greatly compromising its anti-lime effect. In fact, the inventors have surprisingly discovered that, contrary to the knowledge established in the state of the art, increasing the amount of lactic acid in the presence of organic phosphonic acid does not improve the anti-limescale effect of the composition, but undesirably increases the incompatibility with commonly used materials in both the home and workplace and instruments. On the contrary, the decrease in the amount of lactic acid below the concentration normally used in this type of compositions to the claimed amount of lactic acid (from 0.25% to 0.8%) of the compositions of the present invention together with an amount of organic phosphonic acid of 0.1% to 0.5%, it allows optimal stabilization of hydrogen peroxide and the double and broad disinfectant and cleaning effect without compromising safety, toxicity and compatibility with the surfaces to be treated.

As shown in the experimental data, on the one hand, the composition of the present invention has broad-spectrum antimicrobial activity with a short exposure time (approximately 5 minutes against enveloped bacteria and viruses). In particular, the composition has been shown to be effective against gram-positive and gram-negative bacteria, fungi and enveloped viruses without the need to rinse the surface after application, even with low amounts of hydroxyperoxide. In fact, due to its harmlessness, it is also appropriate for the treatment of surfaces that are usually in contact with food.

On the other hand, as also demonstrated in the Examples, the composition of the invention is useful as a cleaning product because it is capable of removing lime, soap (scum, soap scum and stains) and grease from inanimate surfaces, without damaging the treated surface thanks to the very low or no reactivity towards materials, substrates and fabrics. Therefore, the composition of the invention has an effective cleaning activity of any surface regardless of whether a calcareous effect, a soap removal activity and/or a grease removal effect is needed. In fact, the composition of the invention includes the appropriate active cleaning ingredients and achieves a very deep and broad cleaning effect without affecting the disinfectant activity or the stability of the composition.

Finally, the present application also includes a toxicity, irritability and corrosion test that demonstrates that the composition of the invention can be considered non-toxic, non-irritant and safe for use as a disinfectant and cleaner for inanimate surfaces, including those that are formed by or have metals or delicate organic materials. Additionally, the use of the composition of the invention with a low amount of active ingredients, particularly hydrogen peroxide, results in an improved shelf life and facilitates packaging without involving any health and safety risk.

Therefore, the first aspect of the invention refers to a composition comprising: 0.5% to 4% by weight of hydrogen peroxide; from 0.1% to 0.5% by weight of an organic phosphonic acid; from 0.25% to 0.8% by weight of lactic acid; and having a pH of 2 to 3.6.

The second aspect of the invention relates to a process for preparing the composition of the first aspect of the invention.

The third aspect of the invention relates to a use of the composition of the first aspect of the invention as a disinfectant and cleaner.

Finally, the fourth aspect of the invention relates to a method for disinfecting and cleaning an inanimate surface comprising applying a composition as defined in the first aspect of the invention.

Detailed description of the invention

All terms and expressions as used in this application, unless otherwise indicated, will be understood in their usual meaning, as known in the art. Other more specific definitions for certain terms and expressions, as used in the present application, are as set forth below and are intended to apply uniformly throughout the specification and claims, unless a definition expressly set forth otherwise provide a broader definition.

For the purposes of the present invention, any given range includes both the lower and upper ends of the range. Ranges and values given, such as temperatures, times, and the like, should be considered approximate unless specifically stated otherwise.

The term "percent (%) by weight" refers to the percentage of each ingredient in the composition relative to the total weight.

The term "about" or the expression "about", as used herein, refers to a range of values ±10% of a specified value. For example, the expression "about 10" or "about 10" includes ±10% of 10, that is, 9 to 11.

The first aspect relates to a stable disinfectant and cleaner comprising 0.5% to 4% by weight of hydrogen peroxide; 0.1% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.8% by weight of lactic acid; and having a pH of 2 to 3.6.

In one embodiment, the composition comprises 0.5% to 4% by weight of hydrogen peroxide. In one embodiment, the composition comprises from 1% to 3.5% by weight of hydrogen peroxide. In one embodiment, the composition comprises 1% to 3% by weight of hydrogen peroxide. In one embodiment, the composition comprises 1.5% to 3% by weight of hydrogen peroxide. In one embodiment, the composition comprises 1.5% to 2.5% by weight of hydrogen peroxide. In one embodiment, the composition comprises approximately 1.5% by weight of hydrogen peroxide. In one embodiment, the composition comprises from 0.5% to less than 2% by weight of hydrogen peroxide. In one embodiment, the composition comprises from 1% to less than 2% by weight of hydrogen peroxide. In one embodiment, the composition comprises approximately 1.5% by weight of hydrogen peroxide. In one embodiment, the composition comprises equal to or greater than 2% to 4% by weight of hydrogen peroxide. In one embodiment, the composition comprises equal to or greater than 2.5% to 3.5% by weight of hydrogen peroxide. In one embodiment, the composition comprises approximately 2.5% by weight of hydrogen peroxide. As mentioned above, the compositions of the present invention are advantageous because they have a double effect as a disinfectant and cleaner (anti-limescale and soap remover). Particularly, the compositions of the present invention have bactericidal, fungicidal and viricidal activity.

The composition of the present invention comprises 0.1% to 0.5% by weight of an organic phosphonic acid. In one embodiment, the composition comprises 0.18% to 0.4% by weight of an organic phosphonic acid. In one embodiment, the composition comprises 0.2% to 0.35% by weight of an organic phosphonic acid. In one embodiment, the composition comprises 0.2% to 0.3% by weight of an organic phosphonic acid. In one embodiment, the composition comprises about 0.3% by weight of an organic phosphonic acid. The term "organic phosphonic acid" encompasses organic monophosphonic acids and organic biphosphonic acids. In one embodiment, the composition is one wherein the organic phosphonic acid is selected from the group consisting of dimethylaminomethane diphosphonic acid, 1-amino-1-phenylmethane diphosphonic acid, tris(methylenephosphonic) amino acid (ATMP), ethylenediamine tetra-( methylenephosphonic acid) (EDTMP), 2-hydroxyphosphonocarboxylic acid (HPAA), 2-phosphonobutane-1,2,4-tricarboxylic acid (PBTCA), polyhydric alcohol phosphate ester (PAPE), bis-(hexamethylenetriaminepenta(methylenephosphonic acid)) (BHMTPMPA ), aminoacetic acid-N-di-(methylenephosphonic acid), diethylenetriaminepenta(methylene)phosphonic acid (DTMPA) and 1-hydroxyethane-1,1-diphosphonic acid. In one embodiment, the composition is one wherein the organic phosphonic acid is 1-hydroxyethylidene-1,1-diphosphonic acid. The terms 1-hydroxyethylidene-1,1-diphosphonic acid and etidronic acid and the abbreviation HEDP refer to the same compound that is marketed under the name Dequest 2010 LC.

The composition of the invention comprises 0.25% to 0.8% by weight of lactic acid. In one embodiment, the composition comprises 0.25% to 0.75% by weight of lactic acid. In one embodiment, the composition comprises 0.3% to 0.75% by weight of lactic acid. In one embodiment, the composition comprises 0.35% to 0.75% by weight of lactic acid. In one embodiment, the composition comprises 0.35% to 0.5% by weight of lactic acid. In one embodiment, the composition comprises approximately 0.35% by weight of lactic acid. The term "lactic acid" is the international non-proprietary name for 2-hydroxypropionic acid which has the CAS number 50-21-5. The structure of lactic acid corresponds to the following formula:

In one embodiment, the composition comprises:

from 1% to 3.5% by weight of hydrogen peroxide;

from 0.18% to 0.4% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.75% by weight of lactic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition comprises:

from 1.5% to 3% by weight of hydrogen peroxide;

0.2% to 0.3% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.35% to 0.75% by weight of lactic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition comprises:

from 1.5% to 2.5% by weight of hydrogen peroxide;

0.2% to 0.3% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.35% to 0.5% by weight of lactic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition comprises:

about 1.5% by weight hydrogen peroxide;

about 0.3% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; approximately 0.35% by weight of lactic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition comprises:

about 2.5% by weight hydrogen peroxide;

about 0.3% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; approximately 0.35% by weight of lactic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention further comprises one or more additives. In one embodiment, the composition further comprises one or more additives selected from the group consisting of solvents, surfactants, enhancers, pH adjusting agent, pH buffering agents, thickening/viscosity modifying agent, perfumes or fragrances, preservatives; dyes and other colorants; UV ray absorbers or antioxidant agents, fabric softening compositions; static control agents; optical opacifiers and foam regulators.

In one embodiment, the composition of the invention comprises one or more solvents. In one embodiment, the composition of the invention comprises one or more miscible organic solvents. In one embodiment, the composition of the invention comprises one or more miscible organic solvents that are water-miscible organic solvents. Examples of water-miscible solvents include alcohols, ethers, ketones, esters and a mixture thereof. In one embodiment, the composition of the invention comprises one or more water-miscible organic solvents selected from the group consisting of alcohol (C2-Ca), alkyl (C1-C4)-CO-alkyl (C1-C4), alkyl (C1 -C4HO-(C-i-C4)alkyl, (C1-C4)alkyl-CO-O-(C1-C4)alkyl and a mixture thereof If present, the amount of solvents in the compositions of the present invention is. 2 to 7% by weight; in particular 3 to 6% by weight. In one embodiment, the composition of the invention comprises one or more alcohols (C2-Ca). wherein at least one hydrogen atom is substituted with a hydroxyl group and containing the number of carbon atoms specified in the description or claims. The term "alkane" refers to a saturated, branched or linear hydrocarbon, containing the. number of carbon atoms specified in the description or in the claims. Examples include ethanol, n-propanol, isopropanol, butanol, isobutanol and sec-butanol. The term "alkyl" refers to a saturated linear or branched hydrocarbon chain containing the number of carbon atoms specified in the description or claims. Examples include, but are not limited to, the methyl, ethyl, propyl, isopropyl, butyl, isobutyl, sec-butyl and fert-butyl group. The alkyl group may be optionally substituted. In one embodiment, the solvent is one or more alcohols as defined above. In one embodiment, the composition of the invention comprises ethanol as an alcoholic solvent. In one embodiment, the solvent is one or more ethers of formula (C1-C4)-O-(C1-C4)alkyl. In one embodiment, the composition of the invention comprises one or more ethers as solvents selected from the group consisting of (3-methoxy-3-methyl-1-butanol) (MMB), di(propylene glycol) n-butyl ether (marketed under the name Dowanol Dpnb), di(propylene) glycol and a mixture thereof. In one embodiment, the composition comprises di(propylene glycol) n-butyl ether as a solvent. In one embodiment, the composition comprises di(propylene) glycol as a solvent. In one embodiment, the composition comprises a combination of one or more alcohols as defined above and one or more ethers as defined above. In one embodiment, the composition comprises a mixture of ethanol and di(propylene glycol) n-butyl ether as solvents.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

0.1% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.8% by weight of lactic acid;

2 to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol), di(propylene) glycol and mixture thereof; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

from 0.3% to 1% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; 0.2% to 0.8% by weight of lactic acid;

3 to 6% by weight of ethanol; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

from 0.3% to 1% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; 0.2% to 0.8% by weight of lactic acid;

3 to 6% by weight of a mixture of ethanol and di(propylene glycol) n-butyl ether; and having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

from 0.3% to 1% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; 0.2% to 0.8% by weight of lactic acid;

3 to 6% by weight of di(propylene) glycol; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

2 to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol), di(propylene) glycol and mixture thereof; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

3 to 6% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol), di(propylene) glycol and mixture thereof; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

2 to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol), di(propylene) glycol and mixture thereof; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

3 to 6% by weight of ethanol; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

3 to 6% by weight of a mixture of ethanol and di(propylene glycol) n-butyl ether; and having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

3 to 6% by weight of di(propylene) glycol; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

2 to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol), di(propylene) glycol and mixture thereof; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

3 to 6% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol), di(propylene) glycol and mixture thereof; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

All embodiments disclosed in the present invention for the components of the composition (i.e., hydrogen peroxide, organic phosphoric acid and lactic acid), as well as the pH value, also apply to the aforementioned composition comprising one or more solvents.

In one embodiment, the composition of the invention further comprises one or more surfactants as an additive. The term "surfactant" refers to a material that lowers the surface tension of a liquid and the interfacial tension between two liquids, allowing them to spread more easily. Surfactants have a hydrophilic head that is attracted to water molecules and a hydrophobic tail that repels water and simultaneously binds itself to oil and grease in dirt. These opposing forces separate dirt and suspend it in water, having the ability to remove it from surfaces when the surfactants are dissolved in water. If present, the amount of surfactant in the composition of the present invention is 0.1 to 6.5% by weight of the composition. In one embodiment, the amount of surfactant in the composition of the present invention is 0.5% to 5% by weight of the composition. In one embodiment, the amount of surfactant in the composition of the present invention is 1% to 4% by weight of the composition. In one embodiment, the amount of surfactant in the composition of the present invention is 1% to 3% by weight of the composition. In one embodiment, the amount of surfactant in the composition of the present invention is 1.5% to 2% by weight of the composition.

Surfactant can be divided into three different groups: nonionic, ionic (either anionic or cationic) or zwitterionic (or amphoteric where the head of the surfactant contains two groups with opposite charges) surfactant.

In one embodiment, the composition of the invention further comprises one or more amphoteric surfactants. As used herein, "amphoteric surfactant" encompasses a surfactant that contains a head with two oppositely charged groups (e.g., positive and negative). Therefore, amphoteric surfactants can be anionic (negatively charged), cationic (positively charged), or nonionic (no charge) in solution, depending on the acidity or pH of the water. In one embodiment, the composition further comprises one or more amphoteric surfactants selected from the group consisting of amine oxides and betaines. Examples of amine oxides suitable for the present invention include, but are not limited to, decyldimethylaminoxide, dodecyldimethylamine oxide, tridecyldimethylamine oxide, tetradecyldimethylamine oxide, pentadecyldimethylamine oxide, hexadecyldimethylamine oxide, heptadecyldimethylamine oxide, octadecyldimethylamine oxide, dodecyldipropylamine oxide, tetradecyldipropylamine oxide, hexadecyldipropylamine oxide, tetradecyldibutylamine oxide, octadecyldibutylamine oxide, bis(2-hydroxyethyl)dodecylamine oxide, bis(2-hydroxyethyl)-3-dodecoxy-1-hydroxypropylamine oxide, dimethyl-(2- hydroxydodecyl)amine, 3,6,9-trioctadecyldimethylamine oxide or 3-dodecoxy-2-hydroxypropyldi-(2-hydroxyethyl)amine oxide. Examples of betaines suitable for the present invention include, but are not limited to, amidobetaines, amidosulfobetaines, cocodimethyl carboxymethyl betaine, cocoamidopropyl betaine, cocobetaine, lauryl amidopropyl betaine, oleyl betaine, lauryl dimethyl carboxymethyl betaine, lauryl dimethyl alphacarboxyethyl betaine, cetyl dimethyl carboxymethyl betaine, lauryl bis-(2-hydroxyethyl)carboxymethyl betaine, stearyl bis-(2-hydroxypropyl)carboxymethyl betaine, oleyl dimethyl gamma-carboxypropyl betaine, lauryl bis-(2-hydroxypropyl)alpha-carboxyethyl betaine, coco dimethyl sulfopropyl betaine, stearyl dimethyl sulfopropyl betaine , lauryl dimethyl sulfoethyl betaine, or lauryl bis-(2-hydroxyethyl)sulfopropyl betaine. In one embodiment, the composition further comprises one or more amphoteric surfactants selected from the group consisting of amine oxides as defined above. In one embodiment, the composition further comprises decyldimethylaminoxide. Decyldimethylaminoxide is marketed under the name tegotens.® DO. In one embodiment, if present, the amount of amphoteric surfactants is 0.1 to 2.5% by weight of the composition. In one embodiment, if present, the amount of amphoteric surfactants is 0.2 to 1.5% by weight of the composition. In one embodiment, if present, the amount of amphoteric surfactants is 0.3 to 1% by weight of the composition. In one embodiment, if present, the amount of amphoteric surfactants is 0.4 to 1% by weight of the composition. In one embodiment, if present, the amount of amphoteric surfactants is 0.4 to 0.6% by weight of the composition.

In one embodiment, the composition of the invention further comprises one or more nonionic surfactants. Examples of nonionic surfactants suitable for the present invention include, but are not limited to, ethoxylated and propoxylated alcohols, especially C10-20 alcohols that have reacted with 2 to 100 moles of ethylene oxide and/or propylene oxide per mole of alcohol, especially ethoxylates of primary alcohols containing about 8 to 18 carbon atoms in a straight or branched chain configuration that have been reacted with about 5 to 30 moles of ethylene oxide, for example, the ethoxylates of decyl alcohol, cetyl alcohol , lauryl alcohol or myristyl alcohol; ethoxylates of secondary aliphatic alcohols containing 8 to 18 carbon atoms in a straight or branched chain configuration with 5 to 30 moles of ethylene oxide; condensation of aliphatic alcohols containing from about 8 to about 20 carbon atoms with ethylene oxide and propylene oxide; polyethylene glycol and polyethylene oxide; ethoxylated castor oil; ethoxylated hydrogenated castor oil; ethoxylated coconut oil; ethoxylated lanolin; ethoxylated tall oil; ethoxylated tallow alcohol; and sorbitan ester ethoxylates; alkyl polyglucosides, in particular C8/C10 polyglucosides, C8/C10 wheat bran glucoside known under the trade name Appyclean 6781 from Wheat oleo, C12/C14 polyglucosides, polyethoxylated fatty alcohols, in particular C12/C15 alcohol with 7 units ethoxylated, C9/C11 with 4 ethoxylated units, C9/C18 with 5 ethoxylated units, ethoxylated fatty acids such as ethoxylated oleic acids, ethoxylated sorbitan esters such as sorbitan laurate with 20 ethoxylated units, ethoxylated triglycerides such as lard, tallow , peanut oil, butter oil, cottonseed oil, flax oil, olive oil, palm oil, grapeseed oil, fish oil, soybean oil, castor oil, rapeseed oil, oil copra, polyethoxylated coconut oil, alkylpolyglucosamides, glucamides such as capryloyl/caprylmethylglucamide known under the trade name GlucoPure Wet, amine oxides such as C10/C18 alkyl dimethylamine oxides, C8/C22 alkoxyethyldihydroxyethylamine oxides, ethoxylated polyglycerol esters such as cocoate of glyceret 17, glycerin caprylate caprate 7, glycerin stearate 20, ethoxylated amines, ethoxylated fatty amides or copolymers of propylene oxide and ethylene oxides. In one embodiment, the composition of the invention further comprises one or more nonionic surfactants as defined herein. In one embodiment, the composition of the invention further comprises a nonionic surfactant selected from the group consisting of C8/C10 wheat bran glucoside, capryloyl/caprylmethylglucamide and a mixture thereof. If present, the amount of nonionic surfactants in the composition of the present invention is 0% to 4% by weight. In one embodiment, the amount of nonionic surfactants in the composition of the present invention is 0.2% to 4% by weight. In one embodiment, the amount of nonionic surfactants in the composition of the present invention is 0.5% to 2% by weight. In one embodiment, the amount of nonionic surfactants in the composition of the present invention is 1% to 2% by weight. In one embodiment, the amount of nonionic surfactants in the composition of the present invention is 1.2% to 1.7% by weight. In one embodiment, the amount of nonionic surfactants in the composition of the present invention is approximately 1.5% by weight.

In one embodiment, the composition of the invention further comprises a nonionic surfactant which is a C8/C10 wheat bran glucoside in an amount of 0.2 to 4% by weight of the composition. In one embodiment, the composition of the invention further comprises a nonionic surfactant which is a C8/C10 wheat bran glycoside in an amount of 0.5 to 2% by weight of the composition. In one embodiment, the composition of the invention further comprises a nonionic surfactant which is a C8/C10 wheat bran glucoside in an amount of 0.8 to 1.5% by weight of the composition. In one embodiment, the composition of the invention further comprises a nonionic surfactant which is a C8/C10 wheat bran glucoside in an amount of about 1% by weight of the composition.

In one embodiment, the composition of the invention further comprises a nonionic surfactant that is, capryloyl/caprylmethylglucamide in an amount of 0.2 to 4% by weight of the composition. In one embodiment, the composition of the invention further comprises a nonionic surfactant that is, capryloyl/caprylmethylglucamide in an amount of 0.3 to 2% by weight of the composition. In one embodiment, the composition of the invention further comprises a nonionic surfactant that is, capryloyl/caprylmethylglucamide in an amount of 0.4 to 1.5% by weight of the composition. In one embodiment, the composition of the invention further comprises a nonionic surfactant that is, capryloyl/caprylmethylglucamide in an amount of 0.5 to 0.8% by weight of the composition. In one embodiment, the composition of the invention further comprises a nonionic surfactant that is, capryloyl/caprylmethylglucamide in an amount of approximately 0.5% by weight of the composition.

In one embodiment, the composition of the invention further comprises one or more amphoteric surfactants and one or more nonionic surfactants as defined herein. In one embodiment, the composition of the invention further comprises decyldimethylaminoxide (commercially available under the name tegotens® DO) as an amphoteric surfactant and a C8/C10 wheat bran glucoside, capryloyl/caprylmethylglucamide or a mixture thereof as nonionic surfactants.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide; 0.1% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid;

from 0.25% to 0.8% by weight of lactic acid;

from 0.1% to 6.5% by weight of surfactants; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

0.1% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.8% by weight of lactic acid;

from 0.1% to 2.5% by weight of amphoteric surfactants as defined above; particularly decyldimethylaminoxide;

from 0.2% to 4% by weight of nonionic surfactants as defined above; particularly C8/C10 wheat bran glucoside, capryloyl/caprylmethylglucamide or a mixture thereof; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

0.1% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.8% by weight of lactic acid;

from 0.2% to 4% by weight of amphoteric surfactants as defined above; particularly decyldimethylaminoxide; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

0.3% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.8% by weight of lactic acid;

from 0.2% to 4% by weight of nonionic surfactants as defined above; particularly C8/C10 wheat bran glucoside, capryloyl/caprylmethylglucamide or a mixture thereof; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

0.3% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.8% by weight of lactic acid;

from 0.1% to 6.5% by weight of surfactants;

3 to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol) and di(propylene) glycol and mixture thereof; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

0.3% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.8% by weight of lactic acid;

3 to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol) and di(propylene) glycol and mixture thereof;

from 0.1% to 2.5% by weight of amphoteric surfactants as defined above; particularly decyldimethylaminoxide; from 0.2% to 4% by weight of nonionic surfactants as defined above; particularly C8/C10 wheat bran glucoside, capryloyl/caprylmethylglucamide or a mixture thereof; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

0.3% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.8% by weight of lactic acid;

3 to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol) and di(propylene) glycol and mixture thereof;

from 0.2% to 4% by weight of amphoteric surfactants as defined above; particularly decyldimethylaminoxide; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

0.3% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.8% by weight of lactic acid;

3 to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol) and di(propylene) glycol and mixture thereof;

from 0.2% to 4% by weight of nonionic surfactants as defined above; particularly C8/C10 wheat bran glucoside, capryloyl/caprylmethylglucamide or a mixture thereof; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

from 0.1% to 6.5% by weight of surfactants; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

from 0.1% to 2.5% by weight of amphoteric surfactants as defined above; particularly decyldimethylaminoxide;

from 0.2% to 4% by weight of nonionic surfactants as defined above; particularly C8/C10 wheat bran glucoside, capryloyl/caprylmethylglucamide or a mixture thereof; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

from 0.2% to 4% by weight of amphoteric surfactants as defined above; particularly decyldimethylaminoxide; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

from 0.2% to 4% by weight of nonionic surfactants as defined above; particularly C8/C10 wheat bran glucoside, capryloyl/caprylmethylglucamide or a mixture thereof; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

from 0.1% to 6.5% by weight of surfactants;

3 to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol) and di(propylene) glycol and mixture thereof; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

3 to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol) and di(propylene) glycol and mixture thereof;

from 0.1% to 2.5% by weight of amphoteric surfactants as defined above; particularly decyldimethylaminoxide;

from 0.2% to 4% by weight of nonionic surfactants as defined above; particularly C8/C10 wheat bran glucoside, capryloyl/caprylmethylglucamide or a mixture thereof; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

3 to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol) and di(propylene) glycol and mixture thereof;

from 0.2% to 4% by weight of amphoteric surfactants as defined above; particularly decyldimethylaminoxide; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

3 to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol) and di(propylene) glycol and mixture thereof;

from 0.2% to 4% by weight of nonionic surfactants as defined above; particularly C8/C10 wheat bran glucoside, capryloyl/caprylmethylglucamide or a mixture thereof; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

All embodiments disclosed in the present invention for the components of the composition (i.e., hydrogen peroxide, organic phosphoric acid, lactic acid and solvents), as well as the pH value, also apply to the aforementioned composition comprising surfactants .

In one embodiment, the composition of the invention further comprises one or more enhancers. The enhancer is commonly used to stabilize the composition. The term "booster" encompasses chelating agents (chelating agents), sequestering agents (sequestrants), detergent boosters, water-soluble salts thereof and a mixture thereof. For the purposes of the invention, the term "water-soluble enhancer salts" encompasses inorganic alkaline enhancer salts that may be used alone or in admixture with other enhancers, but without limitation, salts of alkali metal carbonates or of ammonia or substituted ammonium, silicates, phosphates and polyphosphates and borates. Water-soluble organic alkaline enhancers that are useful in the present invention include alkanolamines and cyclic amines. Examples of alcohols suitable for the present invention include, but are not limited to, phosphonic acids and phosphonates, phosphates, aminocarboxylates and their derivatives, including salts of hydroxyethylenediaminetetraacetic acid (HEDTA), and diethylenetriaminepentaacetic acid and tetrasodium salt of glutamic acid, N acid, N-diacetic (marketed as Dissolvine GL-47®); pyrophosphates, polyphosphates, ethylenediamine and ethylenediamine derivatives, hydroxy acids and mono-, di- and tri-carboxylates and their corresponding acids, aluminosilicates, nitroloacetates and their derivatives, and mixtures thereof. Examples of organic chelators include polyanionic compositions such as polyacrylic acid compounds, N-hydroxyethylenediaminetriacetic acid (HEDTA), ethylenediaminetetraacetic acid (EDTa), nitrilotriacetic acid (NTA), diethylenetriaminepentaacetic acid (DTPA), ethylenediaminetetrapropionic acid, triethylenetetraaminohexaacetic acid (TTHA), and the respective alkali metal, ammonium and its substituted ammonium salts; aminophosphonates, including ethylenediaminetetramethylene phosphonates, nitrilotrismethylenephosphonates and diethylenetriamine-(pentamethylenephosphonate), for example. Other suitable sequestering agents include water-soluble polycarboxylate polymers. Such homopolymeric and copolymeric chelating agents include polymeric compositions with pendant carboxylic acid (-CO2H) groups and include polyacrylic acid, polymethacrylic acid, polymaleic acid, acrylic acid-methacrylic acid copolymers, acrylic-maleic copolymers, hydrolyzed polyacrylamide, hydrolyzed methacrylamide, hydrolyzed copolymers of acrylamidemethacrylamide, hydrolyzed polyacrylonitrile, hydrolyzed polymethacrylonitrile, hydrolyzed copolymers of acrylonitrilemethacrylonitrile, or mixtures thereof. Water-soluble salts or partial salts of these polymers or copolymers such as their respective alkali metal (e.g., sodium or potassium) or ammonium salts may also be used. Examples of biodegradable aminocarboxylate marketed or derived thereof are Dissolvine GL-38® and Dissolvine GL-47®, both marketed by Akzo; Trilón M® marketed by BASF; Baypure CX100® marketed by Bayer; Versene EDG® marketed by Dow; HIDS® marketed by Nippon Shakubai; Octaquest E30® and Octaquest A65® both marketed by Finetex/Innospec Octel. In one embodiment, the one or more enhancers are aminocarboxylates and their derivatives as defined herein. In one embodiment, the composition further comprises one or more aminocarboxylate enhancers selected from the group consisting of methylglycine N,N-diacetic acid trisodium salt (MGDA- marketed as Dissolvine M-40®) and glutamic acid tetrasodium salt, N,N-diacetic (marketed as Dissolvine GL-38®). In one embodiment, the composition further comprises glutamic acid tetrasodium salt, N,N-diacetic acid (marketed as Dissolvine GL-38®) as a enhancer. If present, the amount of enhancers in the composition of the present invention is 0.04 to 1% by weight. In particular, the amount of aminocarboxylate enhancers, particularly tetrasodium salt of N,N-diacetic acid (marketed as Dissolvine GL-38®), in the composition of the present invention is 0.04 to 0.1% by weight.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

0.1% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.8% by weight of lactic acid;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

0.1% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.8% by weight of lactic acid;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid;

3 to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol) and di(propylene) glycol and mixture thereof; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

0.1% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.8% by weight of lactic acid;

from 0.1% to 6.5% by weight of surfactants;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

0.1% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.8% by weight of lactic acid;

from 0.1% to 2.5% by weight of amphoteric surfactants as defined above; particularly decyldimethylaminoxide;

from 0.2% to 4% by weight of nonionic surfactants as defined above; particularly C8/C10 wheat bran glucoside, capryloyl/caprylmethylglucamide or a mixture thereof;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

0.1% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.8% by weight of lactic acid;

from 0.1% to 2.5% by weight of amphoteric surfactants as defined above; particularly decyldimethylaminoxide;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

0.1% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.8% by weight of lactic acid;

from 0.2% to 4% by weight of nonionic surfactants as defined above; particularly C8/C10 wheat bran glucoside, capryloyl/caprylmethylglucamide or a mixture thereof;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

0.1% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.8% by weight of lactic acid;

from 0.1% to 6.5% by weight of surfactants;

3% to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol) and di(propylene) glycol and mixture thereof;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

0.1% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.8% by weight of lactic acid;

from 0.1% to 2.5% by weight of amphoteric surfactants as defined above; particularly decyldimethylaminoxide;

from 0.2% to 4% by weight of nonionic surfactants as defined above; particularly C8/C10 wheat bran glucoside, capryloyl/caprylmethylglucamide or a mixture thereof;

3% to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol) and di(propylene) glycol and mixture thereof;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

0.1% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.8% by weight of lactic acid;

from 0.1% to 2.5% by weight of amphoteric surfactants as defined above; particularly decyldimethylaminoxide;

3% to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol) and di(propylene) glycol and mixture thereof;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

0.1% to 0.5% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.25% to 0.8% by weight of lactic acid;

from 0.1% to 2.5% by weight of amphoteric surfactants as defined above; particularly decyldimethylaminoxide;

3 to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol) and di(propylene) glycol and mixture thereof;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid;

3 to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol) and di(propylene) glycol and mixture thereof; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

from 0.1% to 6.5% by weight of surfactants;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

from 0.1% to 2.5% by weight of amphoteric surfactants as defined above; particularly decyldimethylaminoxide;

from 0.2% to 4% by weight of nonionic surfactants as defined above; particularly C8/C10 wheat bran glucoside, capryloyl/caprylmethylglucamide or a mixture thereof;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

from 0.1% to 2.5% by weight of amphoteric surfactants as defined above; particularly decyldimethylaminoxide;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

from 0.2% to 4% by weight of nonionic surfactants as defined above; particularly C8/C10 wheat bran glucoside, capryloyl/caprylmethylglucamide or a mixture thereof;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

from 0.1% to 6.5% by weight of surfactants;

3% to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol) and di(propylene) glycol and mixture thereof;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

from 0.1% to 2.5% by weight of amphoteric surfactants as defined above; particularly decyldimethylaminoxide;

from 0.2% to 4% by weight of nonionic surfactants as defined above; particularly C8/C10 wheat bran glucoside, capryloyl/caprylmethylglucamide or a mixture thereof;

3% to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol) and di(propylene) glycol and mixture thereof;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

from 0.1% to 2.5% by weight of amphoteric surfactants as defined above; particularly decyldimethylaminoxide;

3% to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol) and di(propylene) glycol and mixture thereof;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

1% to 3% by weight of hydrogen peroxide;

from 0.2% to 0.35% by weight of an organic phosphonic acid, particularly 1-hydroxyethylidene-1,1-diphosphonic acid; from 0.3% to 0.75% by weight of lactic acid;

from 0.1% to 2.5% by weight of amphoteric surfactants as defined above; particularly decyldimethylaminoxide;

3 to 7% by weight of one or more solvents, particularly ethanol, n-butyl ether of di(propylene glycol) and di(propylene) glycol and mixture thereof;

0.04 to 1% by weight of one or more enhancers, particularly aminocarboxylate enhancers such as tetrasodium salt of glutamic acid, N,N-diacetic acid; and

having a pH of 2 to 3.6; particularly from 2.4 to 3.2.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

from 0.1% to 0.5% by weight of an organic phosphonic acid;

from 0.25% to 0.8% by weight of lactic acid;

from 0.1 to 6.5% by weight of surfactants;

3 to 7% by weight of solvents; and

0 to 1% by weight of enhancers;

the sum of all components being 100% by weight; and

having a pH of 2 to 3.6.

In one embodiment, the composition of the invention comprises:

from 0.5% to 4% by weight of hydrogen peroxide;

0.1% to 0.5% by weight of 1-hydroxyethylidene-1,1-diphosphonic acid (HEDP);

from 0.25% to 0.8% by weight of lactic acid;

from 0.1 to 2.5% by weight of decyldimethylaminoxide;

0.2 to 4% by weight of C8/C10 wheat bran glycoside;

0 to 4% by weight of capryloyl/caprylmethylglucamide;

3 to 7% by weight of ethanol

0 to 1% by weight of tetrasodium salt of glutamic acid, N,N-diacetic acid;

sufficient amount up to 100% by weight of water;

the sum of all components being 100% by weight; and

having a pH of 2 to 3.6.

All embodiments disclosed in the present invention for the components of the composition (i.e., hydrogen peroxide, organic phosphoric acid, lactic acid, solvents, surfactants), as well as the pH value, also apply to the above-mentioned composition which includes enhancers.

Other conventional additives may also be included in the composition of the present invention, provided that each ingredient is compatible with the other ingredients of the composition and the presence of the ingredient does not adversely affect the stability and properties of the composition. Each additional ingredient can be used to modify the composition of the present invention in a conventional manner and can be present in an effective amount, that is, in the amount necessary to achieve the desired disinfectant and cleaning effect without negatively affecting its stability, toxicity and material compatibility. Examples of conventional additives are selected from the group consisting of thickening/viscosity modifying agent, perfumes or fragrances, preservatives; dyes and other colorants; UV ray absorbers or antioxidant agents, fabric softening compositions; static control agents; optical opacifiers, such as polystyrene particles; and foam regulators, such as dimethylpolysiloxane. Appropriate additional conventional additives as defined above and their amounts can be readily determined by those skilled in the art according to the type of formulation being prepared.

As previously disclosed, the composition of the present invention has a pH of 2 to 3.6. In one embodiment, the composition has a pH of 2 to 3.5. In one embodiment, the composition has a pH of 2.4 to 3.5. In one embodiment, the composition has a pH of 2.4 to 3.2. In one embodiment, the composition has a pH of 2.8 to 3.2. The pH is measured using the methods known in the state of the art. In the present invention, pH is measured according to CIPAC guideline MT75.3. This pH is appropriate to have a stable, non-toxic state with efficient disinfectant and cleaning properties.

In one embodiment, the composition further comprises one or more pH adjusting agents. The terms "pH adjusting agent" or "pH regulator" have the same meaning and are used interchangeably. They refer to acids or bases that can be used to adjust the pH of the finished composition to the desired level, without affecting the stability of the composition and its disinfectant and cleaning properties. The acid(s) and/or base(s) may be added to the composition in any suitable form, such as anhydrous, hydrated, aqueous or salt. In one embodiment, the pH adjusting agent is a base. Examples of suitable bases include alkali and alkaline earth metal hydroxides, ammonium hydroxide, substituted ammonium hydroxides (such as primary, secondary, tertiary or quaternary ammonium hydroxides) and mixtures thereof. In one embodiment, the pH adjusting agent is an acid. Examples of suitable acids include sulfur-containing acid, such as a sulfonic acid, sulfuric acid, an alkali metal bisulfate, phosphoric acid and nitric acid. If present, the amount of the pH adjusting agent in the composition of the present invention is such that it has the appropriate pH value of the compositions of the present invention.

In one embodiment, the composition further comprises one or more pH buffering agents. The term "pH buffering agent" is an acid in an amount sufficient to control the pH within the desired acidic pH range of the composition as defined above. The presence of one or more pH buffering agents makes it possible to minimize pH changes, particularly after dilution. Examples of buffering agent of appropriate pH include weak inorganic acids of phosphoric acid, strong organic acids of sulfonic acids, weak organic acids of phosphoric acid, phosphonic acid, boronic acid and mono- or multicarboxylic acid (such as acetic acid, citric acid). If present, the amount of the pH buffering agent of the present invention is 0.25 to 0.50% by weight.

The composition of the first aspect of the invention can be packaged and used to treat a given surface in any suitable format known to one skilled in the art, such as liquid compositions, foam composition, gel composition or impregnated on solid surfaces (such as wipes). In one embodiment, the composition of the invention is a liquid format. In particular, the liquid format is a water-based solution composition that can be presented in the form of a spray, aerosol, bottle, doypack and sachet. The liquid compositions of the present invention may be packaged in manually operated dispensing containers (such as a trigger or pump dispenser). In said dispenser, the liquid composition can be divided into fine liquid droplets resulting in an aerosol/spray that is directed onto the surface to be treated. In one embodiment, the composition of the invention is in gel format. When the composition is a gel, the composition further comprises one or more gelling agents. The appropriate gelling agents and their amounts can be easily determined by those skilled in the art according to the type of formulation being prepared. Examples of suitable gelling agents include, acrylates/palmeth-25 acrylate copolymer (POLYGe L W301), 2-propenoic acid, homopolymer (POLYGEL CA) and a mixture thereof. The gel compositions of the present invention can be packaged in manually operated dispensing containers, bottle, doypack and sachet. In one embodiment, the composition of the invention is in foam format. When the composition is a foam, the composition further comprises one or more foaming agents. Appropriate foaming agents and their amounts can be easily determined by those skilled in the art according to the type of formulation being prepared. Examples of suitable foaming agents include any of the surfactants defined above in the present invention. The foam compositions of the present invention can be packaged in manually operated dispensing containers. In one embodiment, the composition of the invention is in the form of wipes, such as disposable towels, incorporated/impregnated/moistened with the composition of the first aspect of the invention.

The second aspect of the invention relates to a process for preparing the composition of the first aspect of the invention.

The compositions of the present invention can be prepared according to methods well known in the state of the art according to the type of formulation being prepared.

In one embodiment, the process for preparing the composition of the first aspect of the invention comprises: Step a) providing an aqueous mixture of the organic phosphonic acid and, if present, additives (such as surfactants, solvents and enhancers);

Step b) add hydrogen peroxide and lactic acid simultaneously or sequentially to the resulting aqueous mixture obtained in step a) until having a composition that has a pH of 2 to 3.6; and optionally step c) adjust the volume of the mixture obtained in step b) by adding the appropriate amount of water. In one embodiment, the process for preparing the composition of the first aspect of the invention comprises: Step a) providing an aqueous mixture of the organic phosphonic acid and, if present, additives except fragrance additives (such as surfactants, solvents and enhancers);

Step a') add the fragrance to the mixture resulting from step a); and

Step b) add hydrogen peroxide and lactic acid simultaneously or sequentially to the resulting aqueous mixture obtained in step a) until having a composition that has a pH of 2 to 3.6.

In one embodiment, steps a), a'), b) and c) are carried out under continuous stirring. In one embodiment, steps a), a') and b) are carried out at room temperature. The term "ambient temperature" refers to a temperature of the surroundings, without heating or cooling, and is generally 20°C to 25°C.

In one embodiment, step a) is carried out by simultaneously adding the organic phosphonic acid and the additives (if present). In one embodiment, step b) comprises: first, adding the organic phosphonic acid; and secondly the simultaneous or sequential addition of the additives (if present). The addition of the additives can be done in any order.

In one embodiment, step b) is carried out by simultaneously adding hydrogen peroxide and lactic acid. In one embodiment, step b) comprises: first, the addition of hydrogen peroxide followed by the addition of lactic acid.

In one embodiment, step a) comprises mixing 80% to 100% of the total amount of water to provide the aqueous mixture containing the organic phosphonic acid of step a).

In an alternative embodiment, for the preparation of the composition of the first aspect of the invention it comprises: c) providing an aqueous mixture of the organic phosphonic acid, the lactic acid and, if present, the additives (such as surfactants, solvents and enhancers) ; and

d) separately add hydrogen peroxide and water to the mixture resulting from step c), where the addition is carried out simultaneously or sequentially until obtaining a composition that has a pH of 2 to 3.6.

This process is advantageous because it can be done in batches or continuously.

In one embodiment, steps c) and d) are performed with continuous stirring. In one embodiment, steps c) and d) are performed at room temperature.

In one embodiment, step c) is carried out by simultaneously adding the organic phosphonic acid and the additives (if present). The addition of the additives can be done in any order.

The third aspect of the invention relates to the use of the composition of the first aspect of the invention as a disinfectant and cleaner. As used herein, the terms "disinfectant" and "disinfector" have the same meaning and are used interchangeably. They refer to their ability to destroy, prevent, render harmless and/or exert a controlling effect on any harmful organism (including bacteria, fungi, spores, viruses, molds and yeasts), which exist on an inanimate surface.

For the purposes of the invention, a composition is considered effective as a disinfectant with bactericidal and fungicidal activity where the composition complies with the bactericidal and fungicidal activity of the UNE-EN13697: 20l5 standard on surfaces, which includes, among others, Pseudomona aeroginosa and Aspergillus brasiliensis as microorganisms of reference.For example, the composition of the present invention is reduced by at least 4 log units against Pseudomona aeroginosa and at least 3 log units against Aspergillus brasiliensis as shown in the experimental section. And, for the purposes of the invention, a composition is considered effective as a disinfectant with viricidal activity where the composition reduces at least by a number of 4 log units against relevant viruses such as Vaccinia virus and Coronavirus 229E as shown in the experimental section.

The composition of the invention includes the effective amount of each ingredient to perform its disinfectant action. The composition of the present invention is also suitable for use as a cleaning agent. The terms "cleaning agent" or "cleaning composition" refer to a composition that when applied to inanimate surfaces, effectively removes foreign matter located on the surface. For the purposes of the invention, the term "cleaner" encompasses a composition capable of removing lime, soap (scum, soap scum and stains) and grease from inanimate surfaces. For the purposes of the invention, a composition is considered effective as a cleaning agent where laboratory results according to the IKW method (available on the website https://www.ikw.org/fileadmin/ikw/downloads/Haushaltspflege /HP_EQ_AZR_2017_E.pdf on May 5, 2020) show a low number of traces (equal to or less than 2.5) and a cleanliness between 6-10 out of 10; and the elimination of lime and soap residues is greater than 70% as shown in the experimental section.

Also part of the invention is a method of disinfecting and cleaning an inanimate surface comprising contacting the inanimate surface with the composition of the first aspect of the present invention. The term "inanimate surfaces" encompasses hard surfaces such as those typically found in hospital environments (e.g., operating rooms, surgical areas, recovery areas, mobile equipment such as stretchers, beds and the like), medical laboratories, medical treatment environments , gastronomic services, food processing and those found in residential and commercial spaces such as kitchens, toilets, such as tiles, walls, floors, chrome, glass, smooth vinyl, any plastic, laminated wood, table, sinks, kitchen countertops , tableware, sanitary accessories such as sinks, showers, shower curtains, sinks and toilets. The term "inanimate surfaces" also includes objects such as medical instruments and food service equipment, such as utensils.

In one embodiment, the method for disinfecting and cleaning of the present invention comprises contacting the surface with the composition for an exposure time of 1 min to 15 min, depending on the activity to be carried out. As demonstrated in the experimental data, only the compositions of the present invention are non-toxic, non-irritant and allow efficient disinfectant activity and achieve a very deep and at the same time broad cleaning effect with a short exposure time and without causing damage to the surface to be treated.

Throughout the description and in the claims, the word "comprise" and variations thereof are not intended to exclude other technical characteristics, additives, components or steps. Likewise, the word "understand" covers the case of "consist of." Additional objects, advantages and features of the invention will be apparent to those skilled in the art upon examination of the description or may be learned by practicing the invention. The following examples are provided by way of illustration and are not intended to be limiting of the present invention. Likewise, the present invention covers all possible combinations of particular and preferred embodiments described herein.

Examples

1. Compositions

1.1. Compositions of the invention

The qualitative and quantitative composition of the disinfectant and cleaning liquid solutions of the present invention are shown in Tables 1 and 2, where the amount of each of the components is expressed in percentage by weight.

Tables 1 and 2 show the composition of the invention that has an effective cleaning effect and disinfectant activity.

T l 1

continuation

T l 2

1.2. Comparative compositions of the invention

The qualitative and quantitative comparative composition that is outside the scope of the present invention is shown in Table 3, where the amount of each of the components is expressed in percentage by weight.

In particular, comparative compositions 1, 4, 5, 7 and 9 comprise an amount of lactic acid outside the claimed ranges (the amount of lactic acid in Comp. Ex. 1 and 4 is greater than the claimed range, and in the Ex. Comp. 5, 7 and 9 is less than the claimed interval). Furthermore, comparative compositions 1 and 4 do not comprise an organic phosphonic acid; and comparative composition 5 also has a pH value higher than the claimed range. Furthermore, the comparative compositions of Examples 6 and 8 do not contain lactic acid. And, comparative compositions 2 and 3 contain formic acid instead of lactic acid.

T l

continuation

2. Preparation procedure

The compositions of the invention and the comparative composition as defined above were prepared following the general process as defined below using the ingredients and quantities specified in Tables 1, 2 and 3 respectively.

General procedure

Stage a) In a container with 90% of the amount of total water specified in the corresponding table; the organic phosphonic acid, and, if present, additives (such as surfactants, solvents, enhancers and fragrances) were added sequentially under stirring until a clear solution was obtained;

Step b) Hydrogen peroxide was added to the resulting mixture obtained in step b) with stirring, followed by the addition of the acid until the pH of the solution was adjusted to that specified in the corresponding table; and Step c) 20% of the amount of water was added to the solution obtained in step c) to obtain the final composition.

The resulting compositions can be packaged in small 100 ml containers or large 30 Tn reactors.

Alternatively, the fragrances (if present) can be added separately to the rest of the additives (which are added in step a), Particularly, the fragrances can be added to the resulting mixture obtained in step a) while maintaining stirring. until obtaining a homogeneous solution (step a').

3. Stability evaluation

The evaluation of the stability of the compositions of examples 2, 3 and 5 of the present invention and comparative example 4 was carried out. The method used was based on the CIPAC MT46.3 protocol.

Method:

The tested compositions were stored at 54 °C ± 2 °C for a period of 2 weeks in their commercial packaging material (PE bottle). Only Example 5 was stored at 40°C for 12 weeks, which is an equivalent stability condition. The determination of the hydrogen peroxide content of the tested compositions was carried out according to the CIPAC MT46.3 protocol. The % degradation is calculated using the following equation:

(initial %H2O2 - final %H2O2)/initial %H2O2

The determination of the pH value was carried out following the CIPAC MT75.3 guideline.

A second determination of hydrogen peroxide content was measured from doped compositions containing 10 ppm Fe. The % degradation is calculated using the following equation: (initial %H2O2 - final %H2O2)/initial %H2O2.

The results of the stability tests of the tested compositions are summarized in the following Table:

As shown in the results of the physical and chemical evaluation test, there are no significant changes in color, odor, pH values, packaging and weight loss, as well as in the spray characterization test for the tested compositions of the present invention. On the contrary, significant instability changes were observed in the comparative compositions tested that include an amount of lactic acid outside the claimed ranges, which is an amount of approximately 2% but the organic phosphonic acid is absent.

Likewise, the percentage of hydrogen peroxide degraded after subjecting the tested compositions to the stability test conditions shows that hydrogen peroxide is only stable in the composition of the invention, while the comparative compositions have a degree of peroxide degradation of hydrogen equal to or greater than 9%.

Therefore, the overall results show that only the compositions of the present invention comprising hydrogen peroxide, organic phosphonic acid and lactic acid in the claimed amounts comply with the specifications established by FAO/WHO to ensure toxicological safety. and ensure adequate disinfectant and cleaning efficiency.

4. Disinfectant test

The objective of the tests disclosed below is the evaluation of the biocidal activity of the compositions of the present invention in comparison with comparative compositions that are outside the scope of the present invention. In particular, the bactericidal, fungicidal and/or viricidal activity was measured for the compositions tested (Examples 1, 2, 4, 5 and 7; and Comp. Ex. 6, 7 and 8).

The disinfectant test procedure is based on European Standards (Guidance on the Biocidal Product Regulation):

Phase II - stage I: UNE-EN1276:2010 (5 min), UNE-EN1650:2008+A1:2013 (15 min);

Phase II - stage II: UNE-EN13697:2015 (5 min bacteria and 15 min fungi);

Phase II - stage II: DIN-EN16615:2015 adapted to the dirty conditions of the domestic environment (5 min bacteria and 15 min fungi);

Phase II - stage I: UNE-EN14476:2014 (Vaccinia) (5 min); based on EN14476:2013 (H1N1 virus and herpes virus) (5 min); based on NF-EN14476:2013+A2:2019 (human coronavirus 229 E) (5 min);

The microorganisms, fungi and study viruses tested were: Pseudomonas aeruginosa, Staphylococcus aureus, Enterococcus hirae (EH), Escherichia coli, Candida albicans, Aspergillus brasiliensis (AB), H1N1 virus, Human coronavirus 229E and Vaccinia virus.

The conditions for each test are published in the BPR guide (Regulation (EU) 528/2012) and depend on the organisms to be analyzed and the use of the composition. For the current case, the conditions are the following:

- Contact time: 5 min for bacteria and viruses and 15 min for yeasts and molds.

- Test conditions (clean or dirty): Dirty conditions for home care products.

- Temperature: 20 °C

The disinfectant test results are summarized in the following table:

As shown in the table above, the compositions of the present invention are shown to be biocides. In particular, the compositions of the invention show a triple bactericidal, fungicidal and viricidal activity even comprising a low amount of hydrogen peroxide of 0.5 to 2% by weight (Ex. 1, 2, 4 and 5).

At the same time, comparative compositions that do not contain lactic acid (Comp. Ex. 6 and 8) or contain it in a very low amount that is outside the claimed range (Comp. Ex. 7 which has 0.09%) do not They have an efficient disinfectant effect. Surprisingly, the ineffective disinfectant effect is not enhanced even by increasing the amount of hydrogen peroxide up to 2.5% by weight (Comp. Ex. 9).

5. Cleaner test

The objective of the tests disclosed below is the qualitative evaluation of the cleaning capacity of the compositions of the present invention in comparison with comparative compositions that are outside the scope of the present invention. In particular, the lime and soap removal capacity, the trace evaluation test and the degreasing effect are measured.

5.1. Lime and soap test

The lime and soap removal effect of the compositions of the present invention were measured (Ex. 2 and 4). The objective of this test is the qualitative and quantitative evaluation of the cleaning capacity of the above-mentioned tested compositions in terms of removing lime and soap from surfaces.

Particularly, the effect that a consumer can see in domestic cleaning through the use of the tested compositions was evaluated. In particular, the procedure is based on contact for 5 min of the tested compositions with a surface impregnated with a mixture of lime and soap. The hard surface can be a metal or ceramic tile since they are the most representative surfaces in the domestic environment. After 5 min of exposure, the surface should be treated with distilled water and the effectiveness evaluated.

The test procedure is disclosed in this document below:

1. Clean the tile with acidic water.

2. Rinse with distilled water.

3. Dry the tile

4. Prepare the solution for spraying (continue stirring before testing):

to. 85% ethanol

b. 5% calcium stearate

c. 10% distilled water

5. Tare the tile and spray from above and with continuous movements to distribute the product over the entire surface. 3-4 g of solution should be deposited per tile.

6. Continue drying the tile for 1 hour at room temperature.

7. Place the tile in the oven at 180°C for 1 hour.

8. After 1 hour, remove the tile from the oven and let it cool to room temperature.

9. Let it rest for 1 hour.

10. With the tile in a horizontal position, place the rings on top with a separation of a few cm between them. 11. Take 1.5 ml of product with a pipette and distribute it in the gap of the ring.

12. Let it act for 5 minutes.

13. After 5 minutes, place the tile upright and clean it with distilled water.

The ability to remove limescale from the surface shows the effectiveness of the composition on the surface using a visual scale rate. In particular, the scaling rate was determined by evaluating the circle of the tile (exiting the ring). The less lime remains in the circle (brighter circle), the greater the cleaning effectiveness against lime and soap.

The results are expressed as follows:

The degree of lime and soap removal is expressed as a percentage of the initial amount. The higher the percentage, the better the soap and limescale removal effect.

5.2. Trace evaluation test

The trace test of the compositions of the present invention was carried out (Ex. 2 and 4). The objective of this test is the quantitative evaluation of the amount of visual residue remaining on the treated surface after the application of the tested compositions. The amount of visual debris on a surface correlates with its brightness. The greater the number of visual residues, the less shiny the surface will be.

The method used is the HP_EQ_AZR_2017_E protocol (IKW Recommendation for the Quality Assessment of the Product Performance of All-Purpose Cleaners 2014).

The amount of traces on the surface is scored from 0 to 10, with 0 being no presence of traces (total elimination of visual residue) and 10 being no elimination of visual residue. Therefore, the lower the score number, the better the trace removal.

5.3. Degreaser evaluation test

The degreasing evaluation test of the compositions of the present invention was carried out (Ex. 2 and 4). The objective of this test is the quantitative evaluation of the amount of grease and dirt particles remaining on the treated surface after the application of the tested compositions.

The method used is the HP_EQ_AZR_2017_E protocol (IKW Recommendation for the Quality Assessment of the Product Performance of All-Purpose Cleaners 2014).

The amount of fat on the surface is scored from 0 to 10, with 0 being no fat removal and 10 being no fat removal (total fat removal). Therefore, the higher the score number, the better the fat removal.

5.4. Results

The following table summarizes the results of the soap and lime scale test, the trace evaluation test, and the degreaser evaluation test.

As shown in the above results, the compositions of the present invention can be used as cleaning compositions. In particular, they are proven to be highly effective as an anti-limescale agent and also useful for removing soap from commonly used surfaces in both the home and workplace, including delicate surfaces such as metal surfaces and organic-based surfaces. . Likewise, it is also demonstrated that the composition of the present invention is also effective as a degreasing agent while giving shine to the treated surface without damaging it.

6. Material compatibility

6.1. marble block test

The effect on lime of the compositions of the present invention (Ex. 1, 2 and 4) and comparative example 1-4 was carried out by the procedure based on marble block contact.

The objective of this test is the quantitative evaluation of the aggression on a marble slab caused by the previously mentioned tested compositions. In particular, the procedure is based on the contact of marble block specimens with the tested composition for 5 min and after that time, the evaluation of the weight loss of CaCO3 due to the effect of the composition was determined.

The result is expressed as the % CaCO3 loss which is calculated using the following formula:

Weightloss

x 1000 = % of C to C o 3

Starting weight

The following table summarizes the loss of CaCO3 after surface treatment with the tested compositions.

The aforementioned results show that the compositions of the present invention do not have a high impact on CaCO3 deposits although with high concentrations of lactic acid. Likewise, these results also show that the change of lactic acid for another acid such as formic acid in the same amount (Ex. Comp. 2 and 3) does not cause an increase in aggression to the marble slabs either.

6.2. Wood surface test

The compositions of the present invention (Ex. 2 and 5) were subjected to the materials compatibility test based on the UNE-EN 13442 Standard (Wood floors and interior and exterior wood wall coverings. Determination of resistance to chemical agents) changing the surface of the paper on a chalky or metallic surface.

The objective of this test is the qualitative evaluation of the damage caused by the application of the aforementioned tested compositions on the aforementioned hard surfaces. In particular, the objective is the determination of the resistance of the calcareous or metallic element to a predetermined proportion of chemical agents to which it could be exposed during its useful life.

UNE-EN 13442 Method: A paper impregnated with one of the previously mentioned tested compositions was placed on the test surface and covered with a Petri dish to prevent evaporation.

After a specified period of time, the paper is removed, the test surface is washed and dried, and visible changes are analyzed. These changes are evaluated against a numerical classification code.

The procedure of the method is summarized below in this document:

- Place the test surfaces in a horizontal position.

- The piece of filter paper is immersed in the tested composition for (30±1) s, removed with tweezers and the excess is drained off the edge of the container. The filter paper is quickly placed on the test surface and quickly covered with an inverted Petri dish. The filter paper should not touch the walls of the Petri dish.

- The position of each paper impregnated with the tested composition on each test surface is noted. - The duration established for each of the tested surfaces is 24 hours (+/-1). After that time, the Petri dish and filter paper are removed with tweezers. Paper fibers adhered to the test surface are not removed (if any). The excess of tested composition is absorbed with absorbent paper or cloth without rubbing and the surface is allowed to rest for 24 hours without covering.

- After 24 hours of standing, the test surface is cleaned by rubbing it lightly with the absorbent paper or cloth soaked in the cleaning solution and then with another soaked in distilled water. Finally, the surface is carefully cleaned with a dry cloth.

- During this time, the reference area of the test surface that has not been exposed to the tested composition is cleaned and dried in the same manner.

- The tested surface is left uncovered (30 ± 1) min.

Results: The damage caused by the tested compositions was evaluated by visual examination. A numerical value is associated with the tested area compared to the reference area, which has not been exposed to the tested compositions according to the following classification code:

The results of the compatibility test carried out on calcareous and aluminum surfaces are summarized in the following table:

Visual examination of surfaces treated with the compositions of the invention demonstrates that they have moderate-good/very good compatibility with the surface (code value > 3), which means that the use of the composition of the present invention is compatible with the most used material in professional and domestic installations.

7. Toxicological evaluation

7.1. In vitro skin irritation test

The composition of the present invention (Ex. 5) was subjected to use testing under dermatological control by evaluating the skin acceptability of the tested composition, applied under normal conditions of use for 3 weeks.

The objective of this test is the determination of the attack on the integrity of the skin due to lesions in the epidermis and the appearance of an inflammatory reaction in the dermis, resulting in macroscopically visible phenomena, which manifest from redness (erythema) to edema. . In humans, the use test is carried out under dermatological control, allowing to verify the absence of reactions of discomfort or cumulative irritation associated with the application of the tested composition for 3-4 weeks under normal conditions of use, in subjects who met inclusion criteria. specific.

In summary, this test allows us to appreciate the effectiveness and cosmetic acceptability of the tested compositions of the present invention.

Inclusion criteria:

Number of subjects: 22

Gender: both

Age: 18 to 70 years

Origin: Caucasian

Others: 100% sensitive hand skin

Healthy subjects with a history of atopy: 20-25% maximum

Methodology:

Area: hands

Application and duration: once a day at least for 3 weeks

Conditions of application: by the subjects themselves, at home (beginning D1 and ending D21) under normal conditions of use.

Concomitant application of other products: usual cleansing and moisturizing cream.

Skin Acceptability Assessments:

- Clinical examinations by the dermatologist on days D1 and D22.

- Questionnaire to be completed by the subject

Analysis of data:

Calculation of the frequency of occurrence of the following reactions:

- all reactions observed in the entire study

- reactions noted by the subjects themselves (discomfort, irritation)

- reactions observed by the researcher

- reactions that require modification in the application rate, or its interruption

- reactions considered "relevant"

- adverse reactions.

Interpretation of the results obtained in the experimental conditions of use adopted, based on: - the expected effects, according to the study monitor,

- the type of compositions tested

- analysis of the nature, location, intensity, frequency, duration and period of onset of reactions. Conclusions:

The analysis of the results obtained revealed, in terms of irritation or discomfort, a very good acceptability of the composition of the present invention in all the subjects who participated in the study. In particular, the dermatologist observed no abnormal clinical signs after 3 weeks of application.

No subject of any of the 22 healthy adults with sensitive hand skin reported having had or observed, after repeating the application under normal conditions of use, once a day and for at least 3 consecutive weeks, any skin reaction of irritation or discomfort. .

Appointment list

1. UNE-EN13697:2015

2. IKW Method (available on the website https://www.ikw.org/fileadmin/ikw/downloads/Haushaltspflege/HP_EQ_AZR_2017_E.pdf on May 5, 2020 3. CIPAC Guideline MT75.3.

4. UNE-EN1276:2010

5. UNE-EN1650:2008+A1:2013

6. UNE-EN13697:2015

7. DIN-EN16615:2015

8. UNE-EN14476:2014

9. EN14476:2013

10. NF-EN14476:2013+A2:2019

11. BPR Guide (Regulation (EU) 528/2012)

12. Protocol HP_EQ_A<z>R_2017_E (IKW Recommendation for the Quality Assessment of the Product Performance of All-Purpose Cleaners 2014)

13. UNE-EN 13442 (Wood floors and interior and exterior wood wall coverings. Determination of resistance to chemical agents)

Claims (15)

1. A composition comprising: from 0.5% to 4% by weight of hydrogen peroxide; from 0.1% to 0.5% by weight of an organic phosphonic acid; from 0.25% to 0.8% by weight of lactic acid; and having a pH of 2 to 3.6. 2. The composition according to claim 1, comprising: from 1% to 3.5% by weight of hydrogen peroxide; from 0.18% to 0.4% by weight of an organic phosphonic acid; from 0.25% to 0.75% by weight of lactic acid; and having a pH of 2 to 3.6. 3. The composition according to any of claims 1 or 2, comprising: 1% to 3% by weight of hydrogen peroxide; from 0.2% to 0.35% by weight of an organic phosphonic acid; from 0.3% to 0.75% by weight of lactic acid; and having a pH of 2 to 3.6. 4. The composition according to any of claims 1-3, wherein the organic phosphonic acid is 1-hydroxyethylidene-1,1-diphosphonic acid. 5. The composition according to any of claims 1-4, further comprising one or more additives selected from the group consisting of solvents, surfactants, enhancers, pH adjusting agent, pH buffering agents, thickening agent/modifier. viscosity, perfumes or fragrances, preservatives; dyes and other colorants; UV ray absorbers or antioxidant agents, fabric softening compositions; static control agents; optical opacifiers and foam regulators. 6. The composition according to claim 5, wherein the one or more additives are one or more solvents selected from the group consisting of alcohols, ethers, ketones, esters and a mixture thereof. 7. The composition according to claim 6, wherein the one or more solvents are selected from the group consisting of ethanol, di(propylene glycol) n-butyl ether, di(propylene) glycol and a mixture thereof. 8. The composition according to any of claims 5-7, wherein the one or more additives are one or more surfactants selected from the group consisting of amphoteric surfactants, nonionic surfactants and a mixture thereof. 9. The composition according to claim 8, wherein: Amphoteric surfactants comprise one or more amine oxides selected from the group consisting of decyldimethylaminoxide, dodecyldimethylamine oxide, tridecyldimethylamine oxide, tetradecyldimethylamine oxide, pentadecyldimethylamine oxide, hexadecyldimethylamine oxide, heptadecyldimethylamine oxide, octadecyldimethylamine oxide, dodecyldipropylamine oxide, tetradecyldipropylamine oxide, hexadecyldipropylamine oxide, tetradecyldibutylamine oxide, octadecyldibutylamine oxide, bis(2-hydroxyethyl)dodecylamine oxide, bis(2-hydroxyethyl)-3-dodecoxy-1-hydroxypropylamine oxide, dimethyl-(2-hydroxydodecyl)amine oxide, 3,6,9-trioctadecyldimethylamine oxide and 3-dodecoxy-2-hydroxypropyldi-(2-hydroxyethyl)amine oxide; and The one or more nonionic surfactants are selected from the group consisting of C8/C10 wheat bran glucoside, capryloyl/caprylmethylglucamide and a mixture thereof. 10. The composition according to any of claims 5-9, wherein the one or more additives are one or more enhancers selected from the group consisting of chelating agents, sequestering agents, detergent enhancers and a mixture thereof. 11. The composition according to claim 10, wherein the one or more enhancers are selected from the group consisting of methylglycine N,N-diacetic acid trisodium salt; tetrasodium salt of glutamic acid, N,N-diacetic acid and a mixture thereof. 12. The composition according to claim 1, comprising: from 0.5% to 4% by weight of hydrogen peroxide; from 0.1% to 0.5% by weight of an organic phosphonic acid; from 0.25% to 0.8% by weight of lactic acid; from 0.1 to 6.5% by weight of surfactants; 3 to 7% by weight of solvents; and 0 to 1% by weight of enhancers; the sum of all components being 100% by weight; and having a pH of 2 to 3.6. 13. The composition according to claim 1, comprising: from 0.5% to 4% by weight of hydrogen peroxide; 0.1% to 0.5% by weight of 1-hydroxyethylidene-1,1-diphosphonic acid (HEDP); from 0.25% to 0.8% by weight of lactic acid; from 0.1 to 2.5% by weight of decyldimethylaminoxide; 0.2 to 4% by weight of C8/C10 wheat bran glycoside; 0 to 4% by weight of capryloyl/caprylmethylglucamide; 3 to 7% by weight of ethanol 0 to 1% by weight of tetrasodium salt of glutamic acid, N,N-diacetic acid; sufficient amount up to 100% by weight of water; the sum of all components being 100% by weight; and having a pH of 2 to 3.6. 14. Use of the composition defined in any of claims 1-13 as a disinfectant and cleaning agent. 15. A method of disinfecting and cleaning an inanimate surface comprising applying a composition as defined in any of claims 1-13. REFERENCES CITED IN THE DESCRIPTION This list of references cited by the applicant is solely for the convenience of the reader. It is not part of the European patent document. Despite the care taken in compiling the references, errors or omissions cannot be excluded and the EPO denies all liability in this regard. Patent documents cited in the description •EP 20382501[0001] •WO 2006097666 A1[0009]