ES314057A1 - Procedure for the obtaining of esters of carbaminic acid. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the obtaining of esters of carbaminic acid. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES314057A1 ES314057A1 ES0314057A ES314057A ES314057A1 ES 314057 A1 ES314057 A1 ES 314057A1 ES 0314057 A ES0314057 A ES 0314057A ES 314057 A ES314057 A ES 314057A ES 314057 A1 ES314057 A1 ES 314057A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- formula
- atom
- radicals
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 150000002148 esters Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 150000003254 radicals Chemical class 0.000 abstract 12
- -1 heterocyclic radical Chemical class 0.000 abstract 7
- 150000001875 compounds Chemical class 0.000 abstract 6
- 229910052717 sulfur Inorganic materials 0.000 abstract 5
- 125000004434 sulfur atom Chemical group 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 4
- 125000001424 substituent group Chemical group 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000005840 aryl radicals Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C333/02—Monothiocarbamic acids; Derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Emergency Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Process for obtaining esters of carbaminic acid of formula I ** (See formula) ** wherein each of the radicals Ar1 and Ar2 signify an aryl radical or a heterocyclic radical with aromatic character, each of the radicals R1 and R2 means an aliphatic radical or, taken together, a divalent aliphatic radical, each of the R4 groups and R5 means a hydrogen atom, a lower alkyl radical, a halogen atom or the radical of formula Ia ** (See formula) ** one of the radicals X1 and X2 means one sulfur atom or one oxygen atom and the other one a sulfur atom and R5 a hydrogen atom, an aliphatic radical or an araliphatic radical, characterized in that a) in a compound of formula IV ** (See formula) ** where Rº means a transformable substituent on the radical of formula Ia and each of the radicals Rº 3 and Rº 4 means a hydrogen atom, a lower alkyl radical, a halogen atom or the radical Rº, or in a salt thereof , an R substituent is transformed into the radical of formula Ia, or b) in a compound of formula V ** (See formula) ** where R 'means a transformable substituent on the radical of formula Va ** (See formula) ** it is transformed into the radical Va, and if desired, into a compound obtained, in which X 2 signifies an oxygen atom, the latter being replaced by a sulfur atom and/or, if desired, in a compound obtained in wherein R5 signifies a hydrogen atom, the latter being replaced by an aliphatic radical or an araliphatic radical and/or, if desired, a compound obtained where X1 signifies an oxygen atom and X2 is a sulfur atom, isomerized to a compound in which X 1 means a sulfur atom and X 2 an oxygen atom. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US374849A US3395230A (en) | 1964-06-12 | 1964-06-12 | Bis-phenyl thiocarbamate ester compositions |
| US438066A US3352815A (en) | 1965-03-08 | 1965-03-08 | Aralkyl-phenyl nu-aryl-thiocarbamates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES314057A1 true ES314057A1 (en) | 1966-08-01 |
Family
ID=27006798
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0314057A Expired ES314057A1 (en) | 1964-06-12 | 1965-06-10 | Procedure for the obtaining of esters of carbaminic acid. (Machine-translation by Google Translate, not legally binding) |
Country Status (6)
| Country | Link |
|---|---|
| AT (2) | AT258956B (en) |
| BE (1) | BE665352A (en) |
| ES (1) | ES314057A1 (en) |
| FR (4) | FR1472942A (en) |
| GB (1) | GB1080796A (en) |
| NL (1) | NL6507503A (en) |
-
1965
- 1965-05-24 GB GB2187665A patent/GB1080796A/en not_active Expired
- 1965-06-09 FR FR19965A patent/FR1472942A/en not_active Expired
- 1965-06-10 ES ES0314057A patent/ES314057A1/en not_active Expired
- 1965-06-11 NL NL6507503A patent/NL6507503A/xx unknown
- 1965-06-11 AT AT530765A patent/AT258956B/en active
- 1965-06-11 BE BE665352A patent/BE665352A/xx unknown
- 1965-06-11 AT AT967466A patent/AT259573B/en active
- 1965-08-26 FR FR29505A patent/FR5285M/fr not_active Expired
- 1965-08-26 FR FR29507A patent/FR5220M/fr not_active Expired
- 1965-08-26 FR FR29506A patent/FR5286M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1080796A (en) | 1967-08-23 |
| FR5285M (en) | 1967-08-07 |
| BE665352A (en) | 1965-12-13 |
| FR5286M (en) | 1967-08-07 |
| FR1472942A (en) | 1967-03-17 |
| AT258956B (en) | 1967-12-27 |
| FR5220M (en) | 1967-07-10 |
| AT259573B (en) | 1968-01-25 |
| NL6507503A (en) | 1965-12-13 |
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