ES316314A1 - Procedimiento para la produccion de derivados de la podofilotoxina. - Google Patents

Procedimiento para la produccion de derivados de la podofilotoxina.

Info

Publication number: ES316314A1
Authority: ES; Spain
Prior art keywords: signifies; radical; translation; procedure; production
Prior art date: 1964-08-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES0316314A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sandoz AG

Original Assignee

Sandoz AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1964-08-12

Filing date

1965-08-10

Publication date

1966-04-16

1965-08-10 Application filed by Sandoz AG filed Critical Sandoz AG

1966-04-16 Publication of ES316314A1 publication Critical patent/ES316314A1/es

Status Expired legal-status Critical Current

Links

238000004519 manufacturing process Methods 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
150000003254 radicals Chemical class 0.000 abstract 4
125000001424 substituent group Chemical group 0.000 abstract 4
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
125000000204 (C2-C4) acyl group Chemical group 0.000 abstract 1
SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical compound [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 1
RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 abstract 1
229940045696 antineoplastic drug podophyllotoxin derivative Drugs 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
239000012948 isocyanate Substances 0.000 abstract 1
150000002513 isocyanates Chemical class 0.000 abstract 1
125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
GRVDJDISBSALJP-UHFFFAOYSA-N methyloxidanyl Chemical compound [O]C GRVDJDISBSALJP-UHFFFAOYSA-N 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
239000003600 podophyllotoxin derivative Substances 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

ES0316314A 1964-08-12 1965-08-10 Procedimiento para la produccion de derivados de la podofilotoxina. Expired ES316314A1 (es)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
CH1050964A CH454169A (de)	1964-08-12	1964-08-12	Verfahren zur Herstellung von neuen Podophyllotoxin-Derivaten
CH788865		1965-06-04
CH819965		1965-06-11

Publications (1)

Publication Number	Publication Date
ES316314A1 true ES316314A1 (es)	1966-04-16

Family

ID=27175878

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
ES0316314A Expired ES316314A1 (es)	1964-08-12	1965-08-10	Procedimiento para la produccion de derivados de la podofilotoxina.
ES0318460A Expired ES318460A1 (es)	1964-08-12	1965-10-14	Procedimiento para la produccion de derivados de la podofilotoxina.
ES0318461A Expired ES318461A1 (es)	1964-08-12	1965-10-14	Procedimiento para la produccion de derivados de la podofilotoxina.

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
ES0318460A Expired ES318460A1 (es)	1964-08-12	1965-10-14	Procedimiento para la produccion de derivados de la podofilotoxina.
ES0318461A Expired ES318461A1 (es)	1964-08-12	1965-10-14	Procedimiento para la produccion de derivados de la podofilotoxina.

Country Status (14)

Country	Link
AT (1)	AT268540B (fr)
BE (1)	BE668122A (fr)
BR (1)	BR6572038D0 (fr)
CH (1)	CH454169A (fr)
DE (1)	DE1518324A1 (fr)
DK (3)	DK113368B (fr)
ES (3)	ES316314A1 (fr)
FI (1)	FI44410B (fr)
FR (2)	FR1468767A (fr)
GB (1)	GB1114123A (fr)
IL (1)	IL24135A (fr)
NL (1)	NL6510414A (fr)
NO (1)	NO119416B (fr)
OA (1)	OA01792A (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE339423T1 (de) *	2000-11-20	2006-10-15	Song-Bae Kim	Verfahren zur herstellung von 4'-o-substituierten 4'-demethyl-1 desoxypodophyllotoxinderivaten und geometrischen isomeren davon ,und antikrebspräparat, das diese enthält
US7342114B2 (en) *	2003-07-01	2008-03-11	California Pacific Medical Center	Podophyllotoxin derivatives
US10087194B2 (en)	2015-10-27	2018-10-02	California Pacific Medical Center	Podophyllotoxin derivatives and their use
CN106937529B (zh)	2015-10-27	2021-02-05	加州太平洋医疗中心	鬼臼毒素衍生物及其应用

1964
- 1964-08-12 CH CH1050964A patent/CH454169A/de unknown
1965
- 1965-07-30 GB GB32730/65A patent/GB1114123A/en not_active Expired
- 1965-08-06 DE DE19651518324 patent/DE1518324A1/de active Pending
- 1965-08-10 FR FR27816A patent/FR1468767A/fr not_active Expired
- 1965-08-10 BE BE668122D patent/BE668122A/xx unknown
- 1965-08-10 ES ES0316314A patent/ES316314A1/es not_active Expired
- 1965-08-10 NL NL6510414A patent/NL6510414A/xx unknown
- 1965-08-11 OA OA52144A patent/OA01792A/fr unknown
- 1965-08-11 IL IL24135A patent/IL24135A/xx unknown
- 1965-08-11 AT AT823567A patent/AT268540B/de active
- 1965-08-11 BR BR172038/65A patent/BR6572038D0/pt unknown
- 1965-08-11 FI FI1939/65A patent/FI44410B/fi active
- 1965-10-14 ES ES0318460A patent/ES318460A1/es not_active Expired
- 1965-10-14 ES ES0318461A patent/ES318461A1/es not_active Expired
- 1965-11-09 FR FR37802A patent/FR4867M/fr not_active Expired
1966
- 1966-09-21 DK DK490566AA patent/DK113368B/da unknown
- 1966-09-21 DK DK490666AA patent/DK111362B/da unknown
- 1966-11-04 NO NO165461A patent/NO119416B/no unknown
1968
- 1968-03-14 DK DK108468AA patent/DK116294B/da unknown

Also Published As

Publication number	Publication date
CH454169A (de)	1968-04-15
IL24135A (en)	1969-02-27
FR1468767A (fr)	1967-02-10
NL6510414A (fr)	1966-02-14
ES318461A1 (es)	1966-06-01
AT268540B (de)	1969-02-10
FI44410B (fr)	1971-08-02
ES318460A1 (es)	1966-04-01
DK116294B (da)	1969-12-29
DK111362B (da)	1968-08-05
DK113368B (da)	1969-03-17
BR6572038D0 (pt)	1973-08-16
OA01792A (fr)	1970-01-14
FR4867M (fr)	1967-02-27
DE1518324A1 (de)	1969-08-21
NO119416B (fr)	1970-05-19
GB1114123A (en)	1968-05-15
BE668122A (fr)	1966-02-10

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