ES318432A1 - Procedimiento para la obtencion de una amina secundaria. - Google Patents

Procedimiento para la obtencion de una amina secundaria.

Info

Publication number: ES318432A1
Authority: ES; Spain
Prior art keywords: isopropoxy; phenoxy; propane; formula; isopropylamino
Prior art date: 1964-10-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES0318432A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novartis AG

BASF Schweiz AG

Original Assignee

Ciba Geigy AG

Ciba AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1964-10-14

Filing date

1965-10-13

Publication date

1966-07-16

1964-10-14 Priority claimed from CH1336164A external-priority patent/CH455834A/de

1965-08-05 Priority claimed from CH1103365A external-priority patent/CH497378A/de

1965-10-13 Application filed by Ciba Geigy AG, Ciba AG filed Critical Ciba Geigy AG

1966-07-16 Publication of ES318432A1 publication Critical patent/ES318432A1/es

Status Expired legal-status Critical Current

Links

238000000034 method Methods 0.000 title abstract 2
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 2
238000006243 chemical reaction Methods 0.000 abstract 2
239000012458 free base Substances 0.000 abstract 2
TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical group [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
YDOOFGNGBOQBCC-UHFFFAOYSA-N 1-(propan-2-ylamino)-3-(2-propan-2-yloxyphenoxy)propan-2-ol Chemical compound CC(C)NCC(O)COC1=CC=CC=C1OC(C)C YDOOFGNGBOQBCC-UHFFFAOYSA-N 0.000 abstract 1
LXJBPJMZBPNPRD-UHFFFAOYSA-N 1-(propan-2-ylamino)-3-(2-propan-2-yloxyphenoxy)propan-2-one Chemical compound C(C)(C)NCC(COC1=C(C=CC=C1)OC(C)C)=O LXJBPJMZBPNPRD-UHFFFAOYSA-N 0.000 abstract 1
XFXYEKNMJKVAMS-UHFFFAOYSA-N 1-amino-3-(2-propan-2-yloxyphenoxy)propan-2-ol Chemical compound C(C)(C)OC1=C(OCC(CN)O)C=CC=C1 XFXYEKNMJKVAMS-UHFFFAOYSA-N 0.000 abstract 1
GEKWRHKUUMZHKS-UHFFFAOYSA-N 2-[(2-propan-2-yloxyphenoxy)methyl]oxirane Chemical compound CC(C)OC1=CC=CC=C1OCC1OC1 GEKWRHKUUMZHKS-UHFFFAOYSA-N 0.000 abstract 1
ZNCUUYCDKVNVJH-UHFFFAOYSA-N 2-isopropoxyphenol Chemical compound CC(C)OC1=CC=CC=C1O ZNCUUYCDKVNVJH-UHFFFAOYSA-N 0.000 abstract 1
YKBZGEJJKPNRSI-UHFFFAOYSA-N 3-(propan-2-ylamino)propane-1,2-diol Chemical compound CC(C)NCC(O)CO YKBZGEJJKPNRSI-UHFFFAOYSA-N 0.000 abstract 1
SNVXAAGRJNDUPV-UHFFFAOYSA-N 3-amino-4-methyl-1-(2-propan-2-yloxyphenoxy)pentan-2-ol Chemical compound C(C)(C)C(C(COC1=C(C=CC=C1)OC(C)C)O)N SNVXAAGRJNDUPV-UHFFFAOYSA-N 0.000 abstract 1
CIRYSSBUFOLMCE-UHFFFAOYSA-N C(C)(C)OC1=C(OCC(CO)O)C=CC=C1 Chemical compound C(C)(C)OC1=C(OCC(CO)O)C=CC=C1 CIRYSSBUFOLMCE-UHFFFAOYSA-N 0.000 abstract 1
MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical compound [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 1
238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
230000007062 hydrolysis Effects 0.000 abstract 1
238000006460 hydrolysis reaction Methods 0.000 abstract 1
125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
JJWLVOIRVHMVIS-UHFFFAOYSA-N isopropylamine Chemical compound CC(C)N JJWLVOIRVHMVIS-UHFFFAOYSA-N 0.000 abstract 1
AQFROTXMDPNEJE-UHFFFAOYSA-N n-(oxiran-2-ylmethyl)propan-2-amine Chemical compound CC(C)NCC1CO1 AQFROTXMDPNEJE-UHFFFAOYSA-N 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
150000003335 secondary amines Chemical class 0.000 abstract 1
LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Emergency Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Cardiology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ES0318432A 1964-10-14 1965-10-13 Procedimiento para la obtencion de una amina secundaria. Expired ES318432A1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CH1336164A CH455834A (de)	1964-10-14	1964-10-14	Verfahren zur Herstellung des neuen 1-Isopropylamino-2-hydroxy-3-(2'-isopropoxy-phenoxy)-propans oder seinen Salzen
CH1103365A CH497378A (de)	1965-08-05	1965-08-05	Verfahren zur Herstellung des neuen 1-Isopropylamino-2-hydroxy-3-(2'-isopropoxy-phenoxy)-propans und seiner Salze

Publications (1)

Publication Number	Publication Date
ES318432A1 true ES318432A1 (es)	1966-07-16

Family

ID=25707709

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES0318432A Expired ES318432A1 (es)	1964-10-14	1965-10-13	Procedimiento para la obtencion de una amina secundaria.

Country Status (7)

Country	Link
JP (2)	JPS4822688B1 (de)
AT (2)	AT268249B (de)
CH (3)	CH455836A (de)
DE (1)	DE1493568A1 (de)
ES (1)	ES318432A1 (de)
NL (1)	NL6513264A (de)
SE (1)	SE335357B (de)

1964
- 1964-10-14 CH CH1583367A patent/CH455836A/de unknown
- 1964-10-14 CH CH1583167A patent/CH455835A/de unknown
- 1964-10-14 CH CH1583467A patent/CH455837A/de unknown
1965
- 1965-09-30 JP JP40059557A patent/JPS4822688B1/ja active Pending
- 1965-10-13 SE SE13277/65A patent/SE335357B/xx unknown
- 1965-10-13 ES ES0318432A patent/ES318432A1/es not_active Expired
- 1965-10-13 AT AT225667A patent/AT268249B/de active
- 1965-10-13 AT AT920067A patent/AT266084B/de active
- 1965-10-13 NL NL6513264A patent/NL6513264A/xx unknown
1967
- 1967-09-23 JP JP42060898A patent/JPS4825176B1/ja active Pending
1969
- 1969-04-09 DE DE19691493568 patent/DE1493568A1/de active Pending

Also Published As

Publication number	Publication date
CH455835A (de)	1968-05-15
SE335357B (de)	1971-05-24
NL6513264A (de)	1966-04-15
CH455836A (de)	1968-05-15
AT266084B (de)	1968-11-11
DE1493568A1 (de)	1969-04-10
CH455837A (de)	1968-05-15
AT268249B (de)	1969-02-10
JPS4822688B1 (de)	1973-07-07
JPS4825176B1 (de)	1973-07-26

Publication	Publication Date	Title
ES301814A1 (es)	1965-01-01	Procedimiento para la obtencion de nuevos acidos aminicos.
CH614448A5 (en)	1979-11-30	Process for the preparation of novel tertiary amines and their acid addition salts, and compounds thus prepared
ES300822A1 (es)	1964-09-16	Procedimiento para la obtención de nuevos derivados fenilalcanolamínicos
ES308785A1 (es)	1965-12-16	Procedimiento para la preparacion de derivados de benzimidazolona.
ES414956A1 (es)	1976-06-16	Procedimiento para la preparacion de 4-(4-bifenilil)-buta- noles.
ES317257A1 (es)	1966-07-16	Procedimiento para la obtencion de aminas.
ES317256A1 (es)	1966-08-01	Procedimiento para la obtencion de aminas secundarias.
ES320749A1 (es)	1966-11-16	Procedimiento para la obtencion de 1-isopropilamino - 2-hidroxi-3-(o-propargiloxi-fenoxi) - propano.
ES325827A1 (es)	1967-02-16	Procedimiento para producir compuestos de 2-fenoxi-2-fenilacetamida.
ES327297A1 (es)	1967-07-16	Procedimiento para la obtencion de compuestos derivados de la quinazolina.
ES283494A1 (es)	1963-02-16	Procedimiento de preparación de compuestos de acciones terapéuticas
ES310979A1 (es)	1966-01-16	Procedimiento para la preparacion de nuevas ureas sustituidas.
ES307984A1 (es)	1965-06-16	Procedimiento para la preparacion de nuevas amidas de acido ariloxiacetico.
ES307939A1 (es)	1965-06-16	Procedimiento para la obtencion de derivados heterociclicos de urea sulfonica.
ES287547A1 (es)	1963-06-16	Procedimiento para la producción de ácido n-(2,3-dimetilfenil) antranílico y sus sales
ES313320A1 (es)	1965-12-16	Procedimiento para la obtencion de nuevos compuestos pirimidinicos.
ES327104A1 (es)	1967-03-16	Procedimiento para la preparacion de diesteres insaturados.
ES297157A1 (es)	1964-05-16	Procedimiento para la obtenciën de compuestos activos para la circulaciën
ES311820A1 (es)	1965-07-01	Procedimiento para la produccion de derivados indolicos.
ES337051A1 (es)	1968-01-16	Procedimiento para la obtencion de la n-(5 - nitro -2- tia-zolil)-oxamida.
ES408926A1 (es)	1976-03-01	Un procedimiento de preparacion de piperidinas sustituidas.
ES289179A1 (es)	1963-12-16	Procedimiento para preparar sales de (n)-cuasi fosfonio
ES244148A1 (es)	1959-01-16	Procedimiento para la obtenciën de nuevos bencimidazoles
ES314012A1 (es)	1966-03-01	Procedimiento para la obtencion de nuevas tiosemicarbazonas.
ES309744A1 (es)	1966-01-16	Procedimiento para la obtencion de aminas.