ES336150A1 - Amides of Aliphatic Carboxylic Acids their Production and Use - Google Patents
Amides of Aliphatic Carboxylic Acids their Production and UseInfo
- Publication number
- ES336150A1 ES336150A1 ES336150A ES336150A ES336150A1 ES 336150 A1 ES336150 A1 ES 336150A1 ES 336150 A ES336150 A ES 336150A ES 336150 A ES336150 A ES 336150A ES 336150 A1 ES336150 A1 ES 336150A1
- Authority
- ES
- Spain
- Prior art keywords
- reacting
- acid
- formula
- alkanol
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000007933 aliphatic carboxylic acids Chemical class 0.000 title 1
- 150000001408 amides Chemical class 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- CTSLXHKWHWQRSH-UHFFFAOYSA-N oxalyl chloride Chemical compound ClC(=O)C(Cl)=O CTSLXHKWHWQRSH-UHFFFAOYSA-N 0.000 abstract 2
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 abstract 1
- ICSNLGPSRYBMBD-UHFFFAOYSA-N 2-aminopyridine Chemical class NC1=CC=CC=N1 ICSNLGPSRYBMBD-UHFFFAOYSA-N 0.000 abstract 1
- XSBAKONFFCSERK-UHFFFAOYSA-N 2-aminopyridine-3-carbonyl chloride Chemical compound NC1=NC=CC=C1C(Cl)=O XSBAKONFFCSERK-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- 150000001718 carbodiimides Chemical class 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- -1 trihaloethyl ester Chemical class 0.000 abstract 1
- 125000006004 trihaloethyl group Chemical group 0.000 abstract 1
- 239000011701 zinc Substances 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Corsets Or Brassieres (AREA)
Abstract
N-Pyridyl-amides of Formula I wherein R 1 -CO- represents the acyl radical of an alkanoic acid, alkenoic acid or alkapolyene acid having 6 to 22 carbon atoms, R 2 represents hydrogen or C 1-4 alkyl and R 3 represents C 1-4 alkyl, and their acid addition salts, are prepared by esterifying a compound of Formula II The esterification may be performed by reacting a compound II with a diazo-alkane, or with a C 1-4 alkanol in the presence of a carbodiimide, or with carbonyl-1,11-diimidazole followed by reacting the product with a C 1-4 alkanol, or with oxalyl chloride followed by reacting the resulting N-(chlorocarbonyl-pyridyl)-amide with a C 1-4 alkanol. Starting materials of Formula II are prepared by reacting a trihaloethyl ester of Formula III with zinc in a liquid organic acid. Trihaloethyl esters of Formula III are prepared by reacting an amino- or C 1-4 -alkylaminopyridine carboxylic acid with a 2,2,2-trihaloethanol, and acylating the resulting amino- or C 1-4 -alkylamino-pyridine carboxylic acid trihaloethyl ester.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH123866A CH495986A (en) | 1966-01-28 | 1966-01-28 | Aliphatic carboxylic acid amides having antiviral and |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES336150A1 true ES336150A1 (en) | 1968-04-01 |
Family
ID=4205698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES336150A Expired ES336150A1 (en) | 1966-01-28 | 1967-01-27 | Amides of Aliphatic Carboxylic Acids their Production and Use |
Country Status (15)
| Country | Link |
|---|---|
| AT (1) | AT265262B (en) |
| BE (1) | BE693265A (en) |
| CH (1) | CH495986A (en) |
| DE (1) | DE1695008A1 (en) |
| DK (1) | DK115261B (en) |
| ES (1) | ES336150A1 (en) |
| FI (1) | FI48078C (en) |
| FR (1) | FR1510321A (en) |
| GB (1) | GB1179261A (en) |
| GR (1) | GR35674B (en) |
| IL (1) | IL27339A (en) |
| NL (1) | NL6701361A (en) |
| NO (1) | NO122422B (en) |
| SE (1) | SE325571B (en) |
| YU (1) | YU32360B (en) |
-
1966
- 1966-01-28 CH CH123866A patent/CH495986A/en not_active IP Right Cessation
-
1967
- 1967-01-26 FI FI22467A patent/FI48078C/en active
- 1967-01-27 YU YU14967A patent/YU32360B/en unknown
- 1967-01-27 NL NL6701361A patent/NL6701361A/xx unknown
- 1967-01-27 FR FR92774A patent/FR1510321A/en not_active Expired
- 1967-01-27 AT AT80267A patent/AT265262B/en active
- 1967-01-27 GR GR670135674A patent/GR35674B/en unknown
- 1967-01-27 NO NO16659367A patent/NO122422B/no unknown
- 1967-01-27 DK DK50867A patent/DK115261B/en unknown
- 1967-01-27 BE BE693265D patent/BE693265A/xx unknown
- 1967-01-27 DE DE19671695008 patent/DE1695008A1/en active Pending
- 1967-01-27 IL IL2733967A patent/IL27339A/en unknown
- 1967-01-27 SE SE122167A patent/SE325571B/xx unknown
- 1967-01-27 GB GB411567A patent/GB1179261A/en not_active Expired
- 1967-01-27 ES ES336150A patent/ES336150A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK115261B (en) | 1969-09-22 |
| FI48078B (en) | 1974-02-28 |
| BE693265A (en) | 1967-07-27 |
| SE325571B (en) | 1970-07-06 |
| FR1510321A (en) | 1968-01-19 |
| GB1179261A (en) | 1970-01-28 |
| CH495986A (en) | 1970-09-15 |
| AT265262B (en) | 1968-10-10 |
| GR35674B (en) | 1968-10-17 |
| NL6701361A (en) | 1967-07-31 |
| DE1695008A1 (en) | 1971-02-25 |
| YU14967A (en) | 1974-04-30 |
| YU32360B (en) | 1974-10-31 |
| NO122422B (en) | 1971-06-28 |
| IL27339A (en) | 1971-04-28 |
| FI48078C (en) | 1974-06-10 |
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