ES340298A1 - Procedimiento de preparacion de derivados de 1-(5-nitro fu-ril 2-acrilideno)-amino hidantoina. - Google Patents

Procedimiento de preparacion de derivados de 1-(5-nitro fu-ril 2-acrilideno)-amino hidantoina.

Info

Publication number: ES340298A1
Authority: ES; Spain
Prior art keywords: furyl; nitro; group; compounds; hydantoin
Prior art date: 1966-05-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES340298A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Clin Byla SA

Original Assignee

Clin Byla SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1966-05-09

Filing date

1967-05-09

Publication date

1968-06-01

1967-05-09 Application filed by Clin Byla SA filed Critical Clin Byla SA

1968-06-01 Publication of ES340298A1 publication Critical patent/ES340298A1/es

Status Expired legal-status Critical Current

Links

150000001469 hydantoins Chemical class 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 10
HGINCPLSRVDWNT-UHFFFAOYSA-N Acrolein Chemical compound C=CC=O HGINCPLSRVDWNT-UHFFFAOYSA-N 0.000 abstract 4
125000004093 cyano group Chemical group *C#N 0.000 abstract 4
229940091173 hydantoin Drugs 0.000 abstract 4
150000003839 salts Chemical class 0.000 abstract 4
150000008064 anhydrides Chemical class 0.000 abstract 3
WJRBRSLFGCUECM-UHFFFAOYSA-N hydantoin Chemical compound O=C1CNC(=O)N1 WJRBRSLFGCUECM-UHFFFAOYSA-N 0.000 abstract 3
QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 2
125000004423 acyloxy group Chemical group 0.000 abstract 2
229910052783 alkali metal Inorganic materials 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 2
125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 abstract 2
-1 5 - Nitro - 2 - furyl Chemical group 0.000 abstract 1
NLHHRLWOUZZQLW-UHFFFAOYSA-N Acrylonitrile Chemical compound C=CC#N NLHHRLWOUZZQLW-UHFFFAOYSA-N 0.000 abstract 1
VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
239000005977 Ethylene Substances 0.000 abstract 1
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
AKGUXECGGCUDCV-UXBLZVDNSA-N [(e)-benzylideneamino]urea Chemical compound NC(=O)N\N=C\C1=CC=CC=C1 AKGUXECGGCUDCV-UXBLZVDNSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
150000001266 acyl halides Chemical class 0.000 abstract 1
125000001931 aliphatic group Chemical group 0.000 abstract 1
150000001340 alkali metals Chemical class 0.000 abstract 1
125000004450 alkenylene group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004466 alkoxycarbonylamino group Chemical group 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
229910021529 ammonia Inorganic materials 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
229940027988 antiseptic and disinfectant nitrofuran derivative Drugs 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
238000007796 conventional method Methods 0.000 abstract 1
125000004122 cyclic group Chemical group 0.000 abstract 1
TZOORMAATWHZDU-UHFFFAOYSA-N ethyl 3-(benzylideneamino)-2,5-dioxoimidazolidine-1-carboxylate Chemical compound C(C1=CC=CC=C1)=NN1C(=O)N(C(=O)C1)C(=O)OCC TZOORMAATWHZDU-UHFFFAOYSA-N 0.000 abstract 1
VEUUMBGHMNQHGO-UHFFFAOYSA-N ethyl chloroacetate Chemical compound CCOC(=O)CCl VEUUMBGHMNQHGO-UHFFFAOYSA-N 0.000 abstract 1
150000004820 halides Chemical class 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
ORTFAQDWJHRMNX-UHFFFAOYSA-N hydroxidooxidocarbon(.) Chemical compound O[C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-N 0.000 abstract 1
125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
150000002762 monocarboxylic acid derivatives Chemical class 0.000 abstract 1
IAIWVQXQOWNYOU-FPYGCLRLSA-N nitrofural Chemical class NC(=O)N\N=C\C1=CC=C([N+]([O-])=O)O1 IAIWVQXQOWNYOU-FPYGCLRLSA-N 0.000 abstract 1
150000007530 organic bases Chemical class 0.000 abstract 1
238000007911 parenteral administration Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
125000001302 tertiary amino group Chemical group 0.000 abstract 1
238000011200 topical administration Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

ES340298A 1966-05-09 1967-05-09 Procedimiento de preparacion de derivados de 1-(5-nitro fu-ril 2-acrilideno)-amino hidantoina. Expired ES340298A1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR60765A FR1489091A (fr)	1966-05-09	1966-05-09	Nouvelles hydantoïnes et leur préparation
FR71098A FR6481M (fr)	1966-05-09	1966-07-27

Publications (1)

Publication Number	Publication Date
ES340298A1 true ES340298A1 (es)	1968-06-01

Family

ID=26170520

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES340298A Expired ES340298A1 (es)	1966-05-09	1967-05-09	Procedimiento de preparacion de derivados de 1-(5-nitro fu-ril 2-acrilideno)-amino hidantoina.

Country Status (5)

Country	Link
BE (1)	BE698146A (fr)
DE (1)	DE1670627A1 (fr)
ES (1)	ES340298A1 (fr)
FR (2)	FR1489091A (fr)
GB (1)	GB1173212A (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5332832A (en) *	1989-07-26	1994-07-26	Procter & Gamble Pharmaceuticals, Inc.	Nitrofurantoin crystals
PL185120B1 (pl) *	1997-03-17	2003-02-28	Adamed Sp Z Oo	Sposób┴wytwarzania┴1-{[3-(5-nitro-2-furylo)-2-propenylideno]-amino}-2,4-imidazolidynodionu
US20030220415A1 (en) *	2002-05-10	2003-11-27	Auburn University And Vanson Halosource, Inc.	Heterocyclic amine diol compounds and their biocidal derivatives
CN101792433B (zh) *	2009-12-10	2011-11-30	浙江科技学院	一种1-((3-(5-硝基-2-呋喃基)烯丙亚基)氨基)海因合成方法
LV15081B (lv)	2014-05-29	2016-11-20	Olainfarm, A/S	Furazidīna polimorfās formas
CN116283912B (zh) *	2023-01-16	2025-02-14	宜宾屏山纺联科技开发有限公司	一种氨基海因席夫碱4-吡啶季铵盐前体化合物及其制备方法和应用

1966
- 1966-05-09 FR FR60765A patent/FR1489091A/fr not_active Expired
- 1966-07-27 FR FR71098A patent/FR6481M/fr not_active Expired
1967
- 1967-05-06 DE DE19671670627 patent/DE1670627A1/de active Pending
- 1967-05-08 GB GB21364/67A patent/GB1173212A/en not_active Expired
- 1967-05-08 BE BE698146D patent/BE698146A/xx unknown
- 1967-05-09 ES ES340298A patent/ES340298A1/es not_active Expired

Also Published As

Publication number	Publication date
FR1489091A (fr)	1967-07-21
FR6481M (fr)	1968-11-25
DE1670627A1 (de)	1971-02-11
GB1173212A (en)	1969-12-03
BE698146A (fr)	1967-10-16

Publication	Publication Date	Title
GB1301754A (fr)	1973-01-04
GB1447599A (en)	1976-08-25	Derivatives of alpha-methyldopa
ES340298A1 (es)	1968-06-01	Procedimiento de preparacion de derivados de 1-(5-nitro fu-ril 2-acrilideno)-amino hidantoina.
GB1224546A (en)	1971-03-10	5-(nitrofurfurylidine) thiazoline- and thiazolidine 4-ones
GB1367598A (en)	1974-09-18	Derivatives of delta 1-pyrroline their method of preparation and their applications
GB1232787A (fr)	1971-05-19
GB1212460A (en)	1970-11-18	Naphthacene derivatives
GB1141249A (en)	1969-01-29	New quinazoline compounds and methods for their production
GB1173687A (en)	1969-12-10	Pyridyl-Tetrahydroisoquinolines
GB1059175A (en)	1967-02-15	Heterocyclic compounds which have pharmacodynamic activity and/or which are intermediates in the preparation of products having pharmacodynamic activity
GB1441872A (en)	1976-07-07	Nitrobenzophenones
GB1441873A (en)	1976-07-07	Diamino-benzophenones
GB1147832A (en)	1969-04-10	Fluorene xanthene and thioxanthene derivatives
GB1115135A (en)	1968-05-29	Nitroalkenyl aryloxycarboxylic acids
GB1238693A (fr)	1971-07-07
GB1262052A (en)	1972-02-02	Dibenzofuran derivatives
GB1185273A (en)	1970-03-25	Derivatives of Phthalimidines
ES342806A1 (es)	1968-08-16	Procedimiento para la preparacion de derivados de difenila-mina.
ES348973A1 (es)	1969-03-16	Un procedimiento de preparacion del (dioxido-2,5 pirrolidi-no-i)-i (perhidroazepino-i)-4 butino-2.
GB1472344A (en)	1977-05-04	Methylene dibenzocycloheptanes
GB1420759A (en)	1976-01-14	Piperidine derivatives
GB1496072A (en)	1977-12-21	Triazolo-benzodiazepine derivatives
ES351898A1 (es)	1969-06-16	Procedimiento para la preparacion de derivados de dibenzo- ciclohepteno.
GB1315575A (en)	1973-05-02	Schiffs bases from 2-aminoimidazole derivatives and the preparation thereof
ES356167A1 (es)	1970-01-01	Procedimiento para la obtencion de nuevos derivados de te- traciclina.