ES343089A1 - Un procedimiento para preparar alfa-6-deoxitetraciclinas. - Google Patents

Un procedimiento para preparar alfa-6-deoxitetraciclinas.

Info

Publication number: ES343089A1
Authority: ES; Spain
Prior art keywords: deoxy; peroxide; mercaptotetracycline; deoxytetracycline; oxytetracycline
Prior art date: 1966-10-31
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES343089A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Inc

Original Assignee

Pfizer Inc

Charles Pfizer and Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1966-10-31

Filing date

1967-07-15

Publication date

1968-08-16

1967-07-15 Application filed by Pfizer Inc, Charles Pfizer and Co Inc filed Critical Pfizer Inc

1968-08-16 Publication of ES343089A1 publication Critical patent/ES343089A1/es

Status Expired legal-status Critical Current

Links

239000002253 acid Substances 0.000 abstract 3
239000003054 catalyst Substances 0.000 abstract 3
150000003839 salts Chemical class 0.000 abstract 3
MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 2
239000004100 Oxytetracycline Substances 0.000 abstract 2
ZQMIGQNCOMNODD-UHFFFAOYSA-N diacetyl peroxide Chemical compound CC(=O)OOC(C)=O ZQMIGQNCOMNODD-UHFFFAOYSA-N 0.000 abstract 2
229960000625 oxytetracycline Drugs 0.000 abstract 2
OZAIFHULBGXAKX-UHFFFAOYSA-N 2,2'-azo-bis-isobutyronitrile Substances N#CC(C)(C)N=NC(C)(C)C#N OZAIFHULBGXAKX-UHFFFAOYSA-N 0.000 abstract 1
239000004098 Tetracycline Substances 0.000 abstract 1
235000019864 coconut oil Nutrition 0.000 abstract 1
239000003240 coconut oil Substances 0.000 abstract 1
RHMZKSWPMYAOAZ-UHFFFAOYSA-N diethyl peroxide Chemical compound CCOOCC RHMZKSWPMYAOAZ-UHFFFAOYSA-N 0.000 abstract 1
150000001451 organic peroxides Chemical class 0.000 abstract 1
150000002978 peroxides Chemical class 0.000 abstract 1
239000011541 reaction mixture Substances 0.000 abstract 1
MOODSJOROWROTO-UHFFFAOYSA-N salicylsulfuric acid Chemical compound OC(=O)C1=CC=CC=C1OS(O)(=O)=O MOODSJOROWROTO-UHFFFAOYSA-N 0.000 abstract 1
CIHOLLKRGTVIJN-UHFFFAOYSA-N tert‐butyl hydroperoxide Chemical compound CC(C)(C)OO CIHOLLKRGTVIJN-UHFFFAOYSA-N 0.000 abstract 1
229960002180 tetracycline Drugs 0.000 abstract 1
229930101283 tetracycline Natural products 0.000 abstract 1
235000019364 tetracycline Nutrition 0.000 abstract 1
150000003522 tetracyclines Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/32—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of salts of sulfonic acids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES343089A 1966-10-31 1967-07-15 Un procedimiento para preparar alfa-6-deoxitetraciclinas. Expired ES343089A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US59047266A	1966-10-31	1966-10-31

Publications (1)

Publication Number	Publication Date
ES343089A1 true ES343089A1 (es)	1968-08-16

Family

ID=24362405

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES343089A Expired ES343089A1 (es)	1966-10-31	1967-07-15	Un procedimiento para preparar alfa-6-deoxitetraciclinas.

Country Status (17)

Country	Link
US (1)	US3484483A (es)
AT (1)	AT273370B (es)
BE (1)	BE701631A (es)
BR (1)	BR6791293D0 (es)
CH (1)	CH514546A (es)
DE (1)	DE1668534C3 (es)
DK (1)	DK119826B (es)
ES (1)	ES343089A1 (es)
FI (1)	FI43733C (es)
FR (1)	FR1531929A (es)
GB (1)	GB1117407A (es)
GR (1)	GR33711B (es)
IL (1)	IL28267A (es)
IT (1)	IT1056003B (es)
NL (1)	NL6709931A (es)
NO (1)	NO118107B (es)
SE (1)	SE334874B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1459861A (en) *	1973-06-21	1976-12-31	Pfizer	Process for 11a-dehalogenation of 11a-halotetracyclines
DK386784A (da) *	1983-08-17	1985-02-18	Hovione Int Ltd	Fremgangsmaade til fremstilling af alfa-6-desoxy-tetracykliner
PT91333B (pt) *	1989-07-31	1995-05-04	Hovione Sociedade Quimica Sa	Processo para a preparacao de um complexo de rodio

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3165531A (en) *	1962-03-08	1965-01-12	Pfizer & Co C	13-substituted-6-deoxytetracyclines and process utilizing the same

1966
- 1966-10-31 US US590472A patent/US3484483A/en not_active Expired - Lifetime
1967
- 1967-01-26 GB GB4037/67A patent/GB1117407A/en not_active Expired
- 1967-07-04 NO NO168936A patent/NO118107B/no unknown
- 1967-07-05 DK DK34767AA patent/DK119826B/da not_active IP Right Cessation
- 1967-07-05 IL IL28267A patent/IL28267A/en unknown
- 1967-07-05 GR GR670133711A patent/GR33711B/el unknown
- 1967-07-10 FI FI671904A patent/FI43733C/fi active
- 1967-07-15 ES ES343089A patent/ES343089A1/es not_active Expired
- 1967-07-17 BR BR191293/67A patent/BR6791293D0/pt unknown
- 1967-07-18 IT IT38239/67A patent/IT1056003B/it active
- 1967-07-18 CH CH1026567A patent/CH514546A/de not_active IP Right Cessation
- 1967-07-18 DE DE19671668534 patent/DE1668534C3/de not_active Expired
- 1967-07-18 AT AT668367A patent/AT273370B/de active
- 1967-07-18 NL NL6709931A patent/NL6709931A/xx unknown
- 1967-07-18 SE SE10650/67*A patent/SE334874B/xx unknown
- 1967-07-19 FR FR114873A patent/FR1531929A/fr not_active Expired
- 1967-07-20 BE BE701631D patent/BE701631A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE1668534C3 (de)	1973-07-05
SE334874B (es)	1971-05-10
US3484483A (en)	1969-12-16
CH514546A (de)	1971-10-31
FI43733C (fi)	1971-06-10
IL28267A (en)	1971-08-25
NL6709931A (es)	1968-05-01
DE1668534A1 (de)	1972-04-13
AT273370B (de)	1969-08-11
DK119826B (da)	1971-03-01
FR1531929A (fr)	1968-07-05
FI43733B (es)	1971-03-01
NO118107B (es)	1969-11-10
GB1117407A (en)	1968-06-19
GR33711B (el)	1968-01-17
BR6791293D0 (pt)	1973-09-06
DE1668534B2 (es)	1972-12-07
IT1056003B (it)	1982-01-30
BE701631A (es)	1968-01-22

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Legal Events

Date	Code	Title	Description
2007-10-16	FD1A	Patent lapsed	Effective date: 19880222