ES345738A1 - Procedimiento para la obtencion de 2,3,4,4a,5,6-hexahidro- 1h-pirazino (1,2-a) quinolinas. - Google Patents

Procedimiento para la obtencion de 2,3,4,4a,5,6-hexahidro- 1h-pirazino (1,2-a) quinolinas.

Info

Publication number: ES345738A1
Authority: ES; Spain
Prior art keywords: radical; alpha; pyrazino; compound; oxo group
Prior art date: 1966-10-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES345738A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novartis AG

BASF Schweiz AG

Original Assignee

Ciba Geigy AG

Ciba AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1966-10-05

Filing date

1967-10-04

Publication date

1969-01-16

1966-10-05 Priority claimed from CH1436366A external-priority patent/CH493546A/de

1967-10-04 Application filed by Ciba Geigy AG, Ciba AG filed Critical Ciba Geigy AG

1969-01-16 Publication of ES345738A1 publication Critical patent/ES345738A1/es

Status Expired legal-status Critical Current

Links

KVIOIFKWKBDGAV-UHFFFAOYSA-N 58881-41-7 Chemical compound C1=CC=C2N3C(=O)C4=CC5=CC=CC=C5N4C(=O)C3=CC2=C1 KVIOIFKWKBDGAV-UHFFFAOYSA-N 0.000 title abstract 2
229940111121 antirheumatic drug quinolines Drugs 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
150000003248 quinolines Chemical class 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 5
125000001931 aliphatic group Chemical group 0.000 abstract 4
125000004043 oxo group Chemical group O=* 0.000 abstract 4
125000004432 carbon atom Chemical group C* 0.000 abstract 3
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
CHIINPDGHUONJZ-UHFFFAOYSA-N 2,3,4,4a,5,6-hexahydro-1h-pyrazino[1,2-a]quinoline Chemical compound C1=CC=C2N3CCNCC3CCC2=C1 CHIINPDGHUONJZ-UHFFFAOYSA-N 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000003118 aryl group Chemical group 0.000 abstract 2
229910052799 carbon Inorganic materials 0.000 abstract 2
125000005843 halogen group Chemical group 0.000 abstract 2
125000005842 heteroatom Chemical group 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
239000004215 Carbon black (E152) Substances 0.000 abstract 1
125000004442 acylamino group Chemical group 0.000 abstract 1
125000004423 acyloxy group Chemical group 0.000 abstract 1
125000003302 alkenyloxy group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004429 atom Chemical group 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
150000002118 epoxides Chemical class 0.000 abstract 1
230000032050 esterification Effects 0.000 abstract 1
238000005886 esterification reaction Methods 0.000 abstract 1
238000006266 etherification reaction Methods 0.000 abstract 1
238000005755 formation reaction Methods 0.000 abstract 1
229930195733 hydrocarbon Natural products 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000000546 pharmaceutical excipient Substances 0.000 abstract 1
229940125723 sedative agent Drugs 0.000 abstract 1
239000000932 sedative agent Substances 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

ES345738A 1966-10-05 1967-10-04 Procedimiento para la obtencion de 2,3,4,4a,5,6-hexahidro- 1h-pirazino (1,2-a) quinolinas. Expired ES345738A1 (es)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
CH1436366A CH493546A (de)	1966-10-05	1966-10-05	Verfahren zur Herstellung neuer Pyrazino (1,2-a)-chinoline
CH156167		1967-02-02
CH1136567		1967-08-11

Publications (1)

Publication Number	Publication Date
ES345738A1 true ES345738A1 (es)	1969-01-16

Family

ID=27173078

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES345738A Expired ES345738A1 (es)	1966-10-05	1967-10-04	Procedimiento para la obtencion de 2,3,4,4a,5,6-hexahidro- 1h-pirazino (1,2-a) quinolinas.

Country Status (6)

Country	Link
BE (1)	BE704693A (de)
DE (1)	DE1670474A1 (de)
ES (1)	ES345738A1 (de)
FR (1)	FR1549376A (de)
GB (1)	GB1201620A (de)
NL (1)	NL6713506A (de)

1967
- 1967-09-27 DE DE19671670474 patent/DE1670474A1/de active Pending
- 1967-10-03 GB GB4500667A patent/GB1201620A/en not_active Expired
- 1967-10-03 FR FR1549376D patent/FR1549376A/fr not_active Expired
- 1967-10-04 ES ES345738A patent/ES345738A1/es not_active Expired
- 1967-10-04 BE BE704693D patent/BE704693A/xx unknown
- 1967-10-04 NL NL6713506A patent/NL6713506A/xx unknown

Also Published As

Publication number	Publication date
DE1670474A1 (de)	1971-02-11
GB1201620A (en)	1970-08-12
FR1549376A (de)	1968-12-13
NL6713506A (de)	1968-04-08
BE704693A (de)	1968-04-04

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