ES363761A1 - Un metodo de preparacion de 5-amino (sustituido)-bencimida-zoles. - Google Patents

Un metodo de preparacion de 5-amino (sustituido)-bencimida-zoles.

Info

Publication number
ES363761A1
ES363761A1 ES363761A ES363761A ES363761A1 ES 363761 A1 ES363761 A1 ES 363761A1 ES 363761 A ES363761 A ES 363761A ES 363761 A ES363761 A ES 363761A ES 363761 A1 ES363761 A1 ES 363761A1
Authority
ES
Spain
Prior art keywords
compound
benzimidazole
reacting
give
appropriate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES363761A
Other languages
English (en)
Inventor
D R Hoff
H Fisher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES363761A1 publication Critical patent/ES363761A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • E—FIXED CONSTRUCTIONS
    • E21—EARTH OR ROCK DRILLING; MINING
    • E21D—SHAFTS; TUNNELS; GALLERIES; LARGE UNDERGROUND CHAMBERS
    • E21D11/00—Lining tunnels, galleries or other underground cavities, e.g. large underground chambers; Linings therefor; Making such linings in situ, e.g. by assembling
    • E21D11/14—Lining predominantly with metal
    • E21D11/28—Longitudinal struts, i.e. longitudinal connections between adjoining arches

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mining & Mineral Resources (AREA)
  • Epidemiology (AREA)
  • Civil Engineering (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Architecture (AREA)
  • Animal Behavior & Ethology (AREA)
  • Structural Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Geochemistry & Mineralogy (AREA)
  • Geology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ES363761A 1967-02-03 1969-02-17 Un metodo de preparacion de 5-amino (sustituido)-bencimida-zoles. Expired ES363761A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61374667A 1967-02-03 1967-02-03
US69649668A 1968-01-09 1968-01-09

Publications (1)

Publication Number Publication Date
ES363761A1 true ES363761A1 (es) 1970-12-16

Family

ID=27087090

Family Applications (4)

Application Number Title Priority Date Filing Date
ES350083A Expired ES350083A1 (es) 1967-02-03 1968-02-02 Un metodo de preparacion de 5-amino (sustituido)-bencimi- dazoles.
ES363762A Expired ES363762A1 (es) 1967-02-03 1969-02-17 Un metodo para la preparacion de 5-amino (sustituido)-ben- cimidazoles.
ES363761A Expired ES363761A1 (es) 1967-02-03 1969-02-17 Un metodo de preparacion de 5-amino (sustituido)-bencimida-zoles.
ES363760A Expired ES363760A1 (es) 1967-02-03 1969-02-17 Un metodo de preparacion de 5-amino (sustituido)-bencimida-zoles.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES350083A Expired ES350083A1 (es) 1967-02-03 1968-02-02 Un metodo de preparacion de 5-amino (sustituido)-bencimi- dazoles.
ES363762A Expired ES363762A1 (es) 1967-02-03 1969-02-17 Un metodo para la preparacion de 5-amino (sustituido)-ben- cimidazoles.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES363760A Expired ES363760A1 (es) 1967-02-03 1969-02-17 Un metodo de preparacion de 5-amino (sustituido)-bencimida-zoles.

Country Status (19)

Country Link
AT (5) AT301244B (es)
BE (2) BE710081A (es)
CH (5) CH545796A (es)
CS (1) CS162651B2 (es)
CY (1) CY653A (es)
DE (2) DE1795711C3 (es)
DK (1) DK139940B (es)
ES (4) ES350083A1 (es)
FI (1) FI52859C (es)
FR (1) FR1580153A (es)
GB (2) GB1198942A (es)
IE (1) IE31812B1 (es)
IT (1) IT1044176B (es)
NL (1) NL157015B (es)
NO (1) NO126484B (es)
OA (1) OA04036A (es)
SE (1) SE346321B (es)
SU (1) SU540569A3 (es)
YU (1) YU33831B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3711608A (en) * 1971-04-13 1973-01-16 Merck & Co Inc The treatment of pain, fever and inflammation with benzimidazoles
US3983130A (en) * 1972-06-02 1976-09-28 E. R. Squibb & Sons, Inc. Anthelmintic isothiocyanobenzoxazoles
US3985755A (en) * 1972-06-02 1976-10-12 E. R. Squibb & Sons, Inc. Pyridine containing isothiocyanobenzoxazoles
US3853894A (en) * 1972-06-02 1974-12-10 Squibb & Sons Inc Isothiocyanobenzimidazoles
MA19290A1 (fr) * 1980-05-22 1982-04-01 Ciba Geigy Ag Derives du benzole,leur preparaton et leur utilisations therapeutiques .
SE8604566D0 (sv) * 1986-10-27 1986-10-27 Haessle Ab Novel compunds
WO2004041277A1 (en) 2002-11-01 2004-05-21 Merck & Co., Inc. Carbonylamino-benzimidazole derivatives as androgen receptor modulators
EP1675844A1 (en) * 2003-10-23 2006-07-05 Sterix Limited Phenyl carboxamide and sulfonamide derivatives for use as 11-beta-hydroxysteroid dehydrogenase
GB0324792D0 (en) 2003-10-23 2003-11-26 Sterix Ltd Compound
ATE435222T1 (de) * 2003-12-18 2009-07-15 Tibotec Pharm Ltd Aminobenzimidazole und benzimidazole als inhibitoren der replikation von respiratory syncytial virus
RU2410382C2 (ru) * 2005-03-17 2011-01-27 Тиботек Фармасьютикалз Лтд 1, 3-дигидробензимидазол-2-илиденовые амины в качестве ингибиторов репликации респираторного синцитиального вируса

Also Published As

Publication number Publication date
DE1695545A1 (de) 1971-05-06
ES363760A1 (es) 1970-12-16
AT289835B (de) 1971-05-10
IT1044176B (it) 1980-03-20
BE710081A (es) 1968-07-30
AT293378B (de) 1971-10-11
CY653A (en) 1972-08-31
DK139940C (es) 1979-10-15
CH545295A (de) 1974-01-31
CH509318A (de) 1971-06-30
DE1795711B2 (de) 1978-09-21
FI52859B (es) 1977-08-31
GB1198942A (en) 1970-07-15
AT289833B (de) 1971-05-10
ES363762A1 (es) 1970-12-16
IE31812L (en) 1968-08-03
OA04036A (fr) 1979-09-30
NL157015B (nl) 1978-06-15
CS162651B2 (es) 1975-07-15
DE1695545B2 (de) 1978-08-31
YU33831B (en) 1978-06-30
SU540569A3 (ru) 1976-12-25
IE31812B1 (en) 1973-01-10
YU21268A (en) 1977-12-31
FR1580153A (es) 1969-09-05
FI52859C (fi) 1977-12-12
NO126484B (es) 1973-02-12
AT289828B (de) 1971-05-10
DE1795711C3 (de) 1979-05-17
DK139940B (da) 1979-05-21
DE1695545C3 (de) 1979-05-03
NL6801482A (es) 1968-08-05
CH545294A (de) 1974-01-31
GB1198941A (en) 1970-07-15
CH545796A (es) 1974-02-15
BE735281A (es) 1969-12-29
CH545293A (de) 1974-01-31
ES350083A1 (es) 1969-11-16
AT301244B (de) 1972-08-25
SE346321B (es) 1972-07-03
DE1795711A1 (de) 1974-02-28

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