ES367451A1 - Procedure for preparing i-glicosil-5-azacitosinas. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for preparing i-glicosil-5-azacitosinas. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES367451A1
ES367451A1 ES367451A ES367451A ES367451A1 ES 367451 A1 ES367451 A1 ES 367451A1 ES 367451 A ES367451 A ES 367451A ES 367451 A ES367451 A ES 367451A ES 367451 A1 ES367451 A1 ES 367451A1
Authority
ES
Spain
Prior art keywords
glicosil
azacitosinas
translation
preparing
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES367451A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Czech Academy of Sciences CAS
Original Assignee
Czech Academy of Sciences CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Czech Academy of Sciences CAS filed Critical Czech Academy of Sciences CAS
Publication of ES367451A1 publication Critical patent/ES367451A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/12Triazine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Gripping On Spindles (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1-Glycosyl.5.azacytosines of the general formula wherein R is a glycosyl residue, R2 is a hydrogen atom or an alkyl group and R3 and R4 are each a hydrogen atom, an alkyl group or an aralky] group, are prepared by reaction of a per-acylglycosyl isocyanate of the general formula R5-N=C=O, wherein R5 is a per-acylglycosyl residue, with an acylguanidine of the general formula and subjection of the resulting l-(per-acylglycosyl)-5.azacytosine of the general formula to alcoholysis or ammonolysis.
ES367451A 1968-11-12 1969-05-20 Procedure for preparing i-glicosil-5-azacitosinas. (Machine-translation by Google Translate, not legally binding) Expired ES367451A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS770868 1968-11-12

Publications (1)

Publication Number Publication Date
ES367451A1 true ES367451A1 (en) 1971-04-01

Family

ID=5426669

Family Applications (1)

Application Number Title Priority Date Filing Date
ES367451A Expired ES367451A1 (en) 1968-11-12 1969-05-20 Procedure for preparing i-glicosil-5-azacitosinas. (Machine-translation by Google Translate, not legally binding)

Country Status (12)

Country Link
AT (1) AT292205B (en)
BE (1) BE732796A (en)
CH (1) CH507969A (en)
DE (1) DE1935027A1 (en)
DK (1) DK128008B (en)
ES (1) ES367451A1 (en)
FR (1) FR2023018A1 (en)
GB (1) GB1227692A (en)
IT (1) IT1033029B (en)
NL (1) NL6907961A (en)
NO (1) NO126626B (en)
SE (1) SE350048B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2012888C3 (en) * 1970-03-14 1981-04-02 Schering Ag, 1000 Berlin Und 4619 Bergkamen Process for the preparation of 5-azapyrimidine nucleosides
US6943249B2 (en) 2003-03-17 2005-09-13 Ash Stevens, Inc. Methods for isolating crystalline Form I of 5-azacytidine
US7038038B2 (en) 2003-03-17 2006-05-02 Pharmion Corporation Synthesis of 5-azacytidine
US6887855B2 (en) 2003-03-17 2005-05-03 Pharmion Corporation Forms of 5-azacytidine
HUE055911T2 (en) 2008-05-15 2021-12-28 Celgene Corp Oral compositions containing cytidine analogs and methods for their use
JP6289361B2 (en) 2011-03-31 2018-03-07 セルジーン インターナショナル サルル Synthesis of 5-azacytidine

Also Published As

Publication number Publication date
CH507969A (en) 1971-05-31
IT1033029B (en) 1979-07-10
SE350048B (en) 1972-10-16
DE1935027A1 (en) 1970-06-04
BE732796A (en) 1969-10-16
FR2023018A1 (en) 1970-08-07
NO126626B (en) 1973-03-05
DK128008B (en) 1974-02-18
GB1227692A (en) 1971-04-07
NL6907961A (en) 1970-05-14
AT292205B (en) 1971-08-25

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