ES370887A1 - Procedimiento para la preparacion de 4-6-dicloro-4,6-estra-dienos. - Google Patents
Procedimiento para la preparacion de 4-6-dicloro-4,6-estra-dienos.Info
- Publication number
- ES370887A1 ES370887A1 ES370887A ES370887A ES370887A1 ES 370887 A1 ES370887 A1 ES 370887A1 ES 370887 A ES370887 A ES 370887A ES 370887 A ES370887 A ES 370887A ES 370887 A1 ES370887 A1 ES 370887A1
- Authority
- ES
- Spain
- Prior art keywords
- estradiene
- dichloro
- esterified
- formula
- hydroxy group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002158 estradienes Chemical class 0.000 title 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- YZUBKLFLODRYOH-OSHGBCRDSA-N (8R,9S,10R,13S,14S)-4,6-dichloro-13-methyl-1,2,3,8,9,10,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene Chemical compound ClC1=C2C(=C[C@H]3[C@@H]4CCC[C@@]4(C)CC[C@@H]3[C@H]2CCC1)Cl YZUBKLFLODRYOH-OSHGBCRDSA-N 0.000 abstract 1
- FTMSFFBXKBQQIA-PDFKHUOFSA-N (8R,9S,10R,13S,14S)-6-chloro-13-methyl-1,2,3,8,9,10,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene Chemical compound ClC1=C[C@H]2[C@@H]3CCC[C@@]3(C)CC[C@@H]2[C@H]2CCCC=C12 FTMSFFBXKBQQIA-PDFKHUOFSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000001412 tetrahydropyranyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19681793422 DE1793422C3 (de) | 1968-09-13 | 4,6-Dichlor-4,6-östradiene, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel, sowie rac-u.nat. 6-Chlor- lTbeta-acetoxy-ie-methyl-17 a-äthinyl-4,6-östradien-3-on als Ausgangsverbindungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES370887A1 true ES370887A1 (es) | 1971-07-01 |
Family
ID=5707698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES370887A Expired ES370887A1 (es) | 1968-09-13 | 1969-08-26 | Procedimiento para la preparacion de 4-6-dicloro-4,6-estra-dienos. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3812166A (de) |
| AT (1) | AT289307B (de) |
| BE (1) | BE738803A (de) |
| BR (1) | BR6912323D0 (de) |
| CH (1) | CH536294A (de) |
| DK (1) | DK121656B (de) |
| ES (1) | ES370887A1 (de) |
| FR (1) | FR2018070A1 (de) |
| GB (1) | GB1287602A (de) |
| IL (1) | IL32973A (de) |
| NL (1) | NL164041C (de) |
| SE (1) | SE352080B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0111872D0 (en) * | 2001-05-15 | 2001-07-04 | Northwick Park Inst For Medica | Therapeutic agents and methods |
| NZ534912A (en) * | 2002-02-04 | 2007-08-31 | Alfama Investigacao E Desenvol | supramolecule aggregate comprising CO containing organometallic or transition metal complex and anti-inflammatory agent or biphosphonate phosphonate derivative |
| US20080026984A1 (en) * | 2002-02-04 | 2008-01-31 | Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda | Methods for treating inflammatory disease by administering aldehydes and derivatives thereof |
| US7968605B2 (en) * | 2002-02-04 | 2011-06-28 | ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. | Methods for treating inflammatory disease by administering aldehydes and derivatives thereof |
| GB2395432B (en) * | 2002-11-20 | 2005-09-14 | Northwick Park Inst For Medica | Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs |
| GB0601394D0 (en) | 2006-01-24 | 2006-03-01 | Hemocorm Ltd | Therapeutic delivery of carbon monoxide |
| EP2699242B1 (de) | 2011-04-19 | 2017-11-01 | Alfama, Inc. | Kohlenmonoxidfreisetzende moleküle und ihre verwendungen |
| JP6134710B2 (ja) | 2011-07-21 | 2017-05-24 | アルファーマ インコーポレイテッドＡｌｆａｍａ，Ｉｎｃ． | 一酸化ルテニウム放出分子およびその使用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH499505A (de) * | 1966-02-23 | 1970-11-30 | Hoffmann La Roche | Verfahren zur Herstellung von halogenierten Steroiden |
-
1969
- 1969-08-05 CH CH1186569A patent/CH536294A/de not_active IP Right Cessation
- 1969-08-26 ES ES370887A patent/ES370887A1/es not_active Expired
- 1969-08-27 US US00853480A patent/US3812166A/en not_active Expired - Lifetime
- 1969-09-02 DK DK469169AA patent/DK121656B/da not_active IP Right Cessation
- 1969-09-05 AT AT847669A patent/AT289307B/de not_active IP Right Cessation
- 1969-09-05 GB GB44022/69A patent/GB1287602A/en not_active Expired
- 1969-09-09 IL IL32973A patent/IL32973A/en unknown
- 1969-09-10 BR BR212323/69A patent/BR6912323D0/pt unknown
- 1969-09-12 FR FR6931175A patent/FR2018070A1/fr not_active Withdrawn
- 1969-09-12 NL NL6913959.A patent/NL164041C/xx not_active IP Right Cessation
- 1969-09-12 BE BE738803D patent/BE738803A/xx unknown
- 1969-09-12 SE SE12600/69A patent/SE352080B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH536294A (de) | 1973-04-30 |
| US3812166A (en) | 1974-05-21 |
| FR2018070A1 (de) | 1970-05-29 |
| DE1793422A1 (de) | 1971-07-01 |
| DK121656B (da) | 1971-11-15 |
| AT289307B (de) | 1971-04-13 |
| NL6913959A (de) | 1970-03-17 |
| NL164041C (nl) | 1980-11-17 |
| DE1793422B2 (de) | 1977-01-20 |
| IL32973A (en) | 1974-07-31 |
| IL32973A0 (en) | 1969-11-30 |
| SE352080B (de) | 1972-12-18 |
| NL164041B (nl) | 1980-06-16 |
| BE738803A (de) | 1970-03-12 |
| BR6912323D0 (pt) | 1973-03-13 |
| GB1287602A (en) | 1972-09-06 |
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