ES371136A1 - Un procedimiento para preparar penicilinas. - Google Patents

Un procedimiento para preparar penicilinas.

Info

Publication number: ES371136A1
Authority: ES; Spain
Prior art keywords: chlorine; bromine; alcohol; carboalkoxy; substituent
Prior art date: 1968-09-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES371136A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Inc

Original Assignee

Pfizer Inc

Charles Pfizer and Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1968-09-03

Filing date

1969-09-02

Publication date

1972-01-01

1969-09-02 Application filed by Pfizer Inc, Charles Pfizer and Co Inc filed Critical Pfizer Inc

1972-01-01 Publication of ES371136A1 publication Critical patent/ES371136A1/es

Status Expired legal-status Critical Current

Links

229930182555 Penicillin Natural products 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
150000002960 penicillins Chemical class 0.000 title abstract 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 13
239000000460 chlorine Substances 0.000 abstract 9
229910052801 chlorine Inorganic materials 0.000 abstract 9
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 8
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 8
229910052794 bromium Inorganic materials 0.000 abstract 8
125000003545 alkoxy group Chemical group 0.000 abstract 7
125000001424 substituent group Chemical group 0.000 abstract 7
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 6
-1 isopropylphenyl Chemical group 0.000 abstract 6
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 6
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 6
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical group C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 3
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 3
125000001589 carboacyl group Chemical group 0.000 abstract 3
125000001309 chloro group Chemical group Cl* 0.000 abstract 3
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 3
YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical group C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical group C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
125000004849 alkoxymethyl group Chemical group 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
125000005111 carboxyalkoxy group Chemical group 0.000 abstract 2
125000001153 fluoro group Chemical group F* 0.000 abstract 2
229920002554 vinyl polymer Polymers 0.000 abstract 2
NOWKCMXCCJGMRR-UHFFFAOYSA-N Aziridine Chemical group C1CN1 NOWKCMXCCJGMRR-UHFFFAOYSA-N 0.000 abstract 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical group C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical group [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
230000001476 alcoholic effect Effects 0.000 abstract 1
125000002393 azetidinyl group Chemical group 0.000 abstract 1
239000007810 chemical reaction solvent Substances 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000002541 furyl group Chemical group 0.000 abstract 1
125000003392 indanyl group Chemical group C1(CCC2=CC=CC=C12)* 0.000 abstract 1
239000011591 potassium Chemical group 0.000 abstract 1
229910052700 potassium Inorganic materials 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
239000011734 sodium Chemical group 0.000 abstract 1
229910052708 sodium Inorganic materials 0.000 abstract 1
125000000475 sulfinyl group Chemical group [*:2]S([*:1])=O 0.000 abstract 1
125000001712 tetrahydronaphthyl group Chemical group C1(CCCC2=CC=CC=C12)* 0.000 abstract 1
125000005505 thiomorpholino group Chemical group 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C07C57/34—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings containing more than one carboxyl group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

ES371136A 1968-09-03 1969-09-02 Un procedimiento para preparar penicilinas. Expired ES371136A1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US75708768A	1968-09-03	1968-09-03
US83048169A	1969-06-04	1969-06-04

Publications (1)

Publication Number	Publication Date
ES371136A1 true ES371136A1 (es)	1972-01-01

Family

ID=27116322

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES371136A Expired ES371136A1 (es)	1968-09-03	1969-09-02	Un procedimiento para preparar penicilinas.

Country Status (9)

Country	Link
JP (1)	JPS4927196B1 (de)
AT (1)	AT306232B (de)
CH (1)	CH520708A (de)
DK (1)	DK137048B (de)
ES (1)	ES371136A1 (de)
FI (1)	FI52867C (de)
NL (1)	NL155834B (de)
NO (1)	NO138884C (de)
SE (1)	SE396390B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6139693U (ja) *	1984-08-17	1986-03-13	三菱重工業株式会社	上部構造物姿勢調整式船舶

1969
- 1969-08-29 DK DK465269A patent/DK137048B/da not_active IP Right Cessation
- 1969-09-01 CH CH1321869A patent/CH520708A/de not_active IP Right Cessation
- 1969-09-02 ES ES371136A patent/ES371136A1/es not_active Expired
- 1969-09-02 NO NO351869A patent/NO138884C/no unknown
- 1969-09-03 FI FI253969A patent/FI52867C/fi active
- 1969-09-03 SE SE1219769A patent/SE396390B/xx unknown
- 1969-09-03 NL NL6913416A patent/NL155834B/xx not_active IP Right Cessation
- 1969-09-03 JP JP6939669A patent/JPS4927196B1/ja active Pending
- 1969-09-03 AT AT839769A patent/AT306232B/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
AT306232B (de)	1973-03-26
JPS4927196B1 (de)	1974-07-16
NL6913416A (de)	1970-03-05
DK137048C (de)	1978-06-12
DK137048B (da)	1978-01-09
FI52867C (fi)	1977-12-12
SE396390B (sv)	1977-09-19
FI52867B (de)	1977-08-31
NO138884C (no)	1978-11-29
NL155834B (nl)	1978-02-15
CH520708A (de)	1972-03-31
NO138884B (no)	1978-08-21

Legal Events

Date	Code	Title	Description
2007-10-16	FD1A	Patent lapsed	Effective date: 19911017

Publication	Publication Date	Title
ES420211A1 (es)	1976-03-16	Un procedimiento para preparar 4-hidroxi-6-arilpirimidinas.
ES391299A1 (es)	1975-11-01	Procedimiento para la preparacion de n-alil 2 - arilamino -imidazolinas (2) sustituidas.
ES417333A1 (es)	1976-02-16	Procedimiento de preparacion de nuevos derivados de (4'- (3''-indolil)piperidino)alcohil-arilcetonas.
ES432952A1 (es)	1977-02-16	Procedimiento para preparar derivado de vincamina.
ES472563A1 (es)	1979-10-16	Procedimiento de obtencion de las 4-(quinazolinil) n-aral- coil piperidinas
IE33270L (en)	1970-02-20	Dibenzodiazepines.
ES440030A1 (es)	1977-02-16	Un procedimiento para preparar nuevos derivados de 2-ami- noindano.
ES410855A1 (es)	1976-03-01	Procedimiento para la obtencion de derivados de benzociclo-heptatiofeno.
ES449777A1 (es)	1977-08-16	Un procedimiento para la preparacion de n-(5-tetrazolil)-pi-rimido (1, 2-a) quinolin-2-carboxamidas.
ES399003A1 (es)	1974-11-01	Procedimiento para la preparacion de 2-arilamino-imidazoli-nas-(2) sustituidas.
ES472703A1 (es)	1979-10-16	Un procedimiento para preparar derivados del acido oxanilico
ES394484A1 (es)	1974-02-16	Procedimiento para la preparacion de derivados 1,4-benzo- diazepinicos.
ES406726A1 (es)	1975-10-01	Un procedimiento para preparar dimetilsulfoxidos y dimetil-sulfonas de acido benzoico sustituido.
ES321807A1 (es)	1966-06-16	Procedimiento para la sintesis de nuevos derivados de la 1,2,3,6-tetrahidropiridina.
GB1435847A (en)	1976-05-19	Esters of alpha-alkylidene-aminobenzyl penicillins
ES423230A1 (es)	1976-06-16	Un procedimiento para la preparacion de poliarilimidazolas.
ES428622A1 (es)	1976-08-16	Procedimiento de obrencion de derivados de 1,4-benzodiazepina.
ES366692A3 (es)	1971-03-16	Procedimiento para la produccion de derivados del alcohol bencilico.
ES414805A1 (es)	1976-03-16	Un procedimiento para preparar monoesteres de alfa-carboxi-bencilpenicilina.
ES422447A1 (es)	1976-04-16	Procedimiento para la preparacion de 1-(tetrahidro-2-pira- nil)-indazoles sustituidos.
ES385473A1 (es)	1973-05-01	Procedimiento para la preparacion de nuevos butanoles ter- ciarios basicamente sustituidos.
ES8204435A1 (es)	1982-04-16	Un procedimiento para la preparacion de 2-(1-piperacinil)-4-(pirimidinaminas)
ES426553A1 (es)	1976-09-01	Procedimiento para preparar 2-formilquinoxalina-1.4-diosidoximas.
ES458006A1 (es)	1978-03-16	Procedimiento para la obtencion de nuevos derivados cefalos-poranicos.
ES404874A1 (es)	1976-01-01	Procedimiento para la obtencion de derivados de la piridi- na.