ES382549A1 - Un procedimiento para la preparacion de nuevas 2-amino-al- cohil-amino-tieno (3,2-d)piridinas. - Google Patents

Un procedimiento para la preparacion de nuevas 2-amino-al- cohil-amino-tieno (3,2-d)piridinas.

Info

Publication number: ES382549A1
Authority: ES; Spain
Prior art keywords: group; general formula; atom; signifies; amino
Prior art date: 1969-08-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES382549A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Boehringer Ingelheim Pharma GmbH and Co KG

Original Assignee

Dr Karl Thomae GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1969-08-08

Filing date

1970-08-07

Publication date

1973-04-01

1969-08-08 Priority claimed from DE19691940572 external-priority patent/DE1940572A1/de

1970-07-02 Priority claimed from DE19702032686 external-priority patent/DE2032686A1/de

1970-07-02 Priority claimed from DE19702032687 external-priority patent/DE2032687A1/de

1970-08-07 Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH

1973-04-01 Publication of ES382549A1 publication Critical patent/ES382549A1/es

Status Expired legal-status Critical Current

Links

238000000034 method Methods 0.000 title abstract 2
RQMWVVBHJMUJNZ-UHFFFAOYSA-N 4-chloropyridin-2-amine Chemical compound NC1=CC(Cl)=CC=N1 RQMWVVBHJMUJNZ-UHFFFAOYSA-N 0.000 title 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
125000004432 carbon atom Chemical group C* 0.000 abstract 3
239000002253 acid Substances 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
150000007522 mineralic acids Chemical class 0.000 abstract 2
229910052757 nitrogen Inorganic materials 0.000 abstract 2
125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
150000007524 organic acids Chemical class 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 1
125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
230000001476 alcoholic effect Effects 0.000 abstract 1
125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
150000001412 amines Chemical class 0.000 abstract 1
125000004429 atom Chemical group 0.000 abstract 1
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
125000002950 monocyclic group Chemical group 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1
125000006239 protecting group Chemical group 0.000 abstract 1
230000001681 protective effect Effects 0.000 abstract 1
150000003230 pyrimidines Chemical class 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
125000003396 thiol group Chemical group [H]S* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Slide Fasteners (AREA)

ES382549A 1969-08-08 1970-08-07 Un procedimiento para la preparacion de nuevas 2-amino-al- cohil-amino-tieno (3,2-d)piridinas. Expired ES382549A1 (es)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE19691940572 DE1940572A1 (de)	1969-08-08	1969-08-08	Neue 2-Aminoalkylamino-thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
DE19702032686 DE2032686A1 (de)	1970-07-02	1970-07-02	Verfahren zur Herstellung von neuen 2 Aminoalkylamino thieno eckige Klammer auf 3,2 d eckige Klammer zu Pynmidinen
DE19702032687 DE2032687A1 (en)	1970-07-02	1970-07-02	Cardiovascular 2-aminoalkylamino-thienopyrimidines - and 4-morpholino derivatives from 4-diethanolamino-compounds by intramolecular cyclisa

Publications (1)

Publication Number	Publication Date
ES382549A1 true ES382549A1 (es)	1973-04-01

Family

ID=27182086

Family Applications (5)

Application Number	Title	Priority Date	Filing Date
ES382550A Expired ES382550A1 (es)	1969-08-08	1970-08-07	Procedimiento para la preparacion de nuevas 2-aminoalcohi- lamino-tieno (3,2-d) pirimidinas.
ES382551A Expired ES382551A1 (es)	1969-08-08	1970-08-07	Un procedimiento para la preparacion de nuevas 2-amino-al- cohil-amino-tieno (3,2-d)pirimidinas.
ES382548A Expired ES382548A1 (es)	1969-08-08	1970-08-07	Un procedimiento para la preparacion de nuevas 2-amino-al- cohil-amino-tieno (3,2-d)piridinas.
ES382552A Expired ES382552A1 (es)	1969-08-08	1970-08-07	Procedimiento para la preparacion de nuevas 2-aminoalcohi- lamino tieno (3,2-d) pirimidinas.
ES382549A Expired ES382549A1 (es)	1969-08-08	1970-08-07	Un procedimiento para la preparacion de nuevas 2-amino-al- cohil-amino-tieno (3,2-d)piridinas.

Family Applications Before (4)

Application Number	Title	Priority Date	Filing Date
ES382550A Expired ES382550A1 (es)	1969-08-08	1970-08-07	Procedimiento para la preparacion de nuevas 2-aminoalcohi- lamino-tieno (3,2-d) pirimidinas.
ES382551A Expired ES382551A1 (es)	1969-08-08	1970-08-07	Un procedimiento para la preparacion de nuevas 2-amino-al- cohil-amino-tieno (3,2-d)pirimidinas.
ES382548A Expired ES382548A1 (es)	1969-08-08	1970-08-07	Un procedimiento para la preparacion de nuevas 2-amino-al- cohil-amino-tieno (3,2-d)piridinas.
ES382552A Expired ES382552A1 (es)	1969-08-08	1970-08-07	Procedimiento para la preparacion de nuevas 2-aminoalcohi- lamino tieno (3,2-d) pirimidinas.

Country Status (14)

Country	Link
US (1)	US3838121A (es)
JP (1)	JPS519759B1 (es)
BE (1)	BE754606A (es)
BG (1)	BG17591A3 (es)
CH (5)	CH547300A (es)
ES (5)	ES382550A1 (es)
FI (1)	FI51939C (es)
FR (1)	FR2068478B1 (es)
IE (1)	IE34687B1 (es)
IL (1)	IL35078A (es)
NL (1)	NL7011592A (es)
NO (1)	NO130538C (es)
PH (1)	PH9574A (es)
SE (1)	SE386449B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6187777B1 (en)	1998-02-06	2001-02-13	Amgen Inc.	Compounds and methods which modulate feeding behavior and related diseases
US20070179161A1 (en) *	2003-03-31	2007-08-02	Vernalis (Cambridge) Limited.	Pyrazolopyrimidine compounds and their use in medicine
GB0423653D0 (en) *	2004-10-25	2004-11-24	Piramed Ltd	Pharmaceutical compounds
CN101163706A (zh) *	2005-04-21	2008-04-16	贝林格尔·英格海姆国际有限公司	用于治疗炎性疾病的二氢噻吩并嘧啶
EP1847543A1 (de)	2006-04-19	2007-10-24	Boehringer Ingelheim Pharma GmbH & Co. KG	Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
CN101479274B (zh) *	2006-04-26	2013-06-12	霍夫曼-拉罗奇有限公司	药用化合物
RU2439074C2 (ru) *	2006-04-26	2012-01-10	Ф. Хоффманн-Ля Рош Аг	ПРОИЗВОДНОЕ ТИЕНО[3,2-d]ПИРИМИДИНА В КАЧЕСТВЕ ИНГИБИТОРА ФОСФАТИДИЛИНОЗИТОЛ-3-КИНАЗЫ (РI3К)
JP5291616B2 (ja) *	2006-04-26	2013-09-18	ジェネンテック，インコーポレイテッド	ホスホイノシチド３−キナーゼ抑制剤化合物およびその使用方法
JP5500990B2 (ja) *	2006-12-07	2014-05-21	エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト	ホスホイノシチド３−キナーゼ阻害剤化合物及び使用方法
WO2008070740A1 (en) *	2006-12-07	2008-06-12	F.Hoffmann-La Roche Ag	Phosphoinositide 3-kinase inhibitor compounds and methods of use
CA2702524A1 (en)	2007-10-19	2009-04-23	Boehringer Ingelheim International Gmbh	Heterocycle-substituted piperazino-dihydrothienopyrimidines
CA2702518A1 (en)	2007-10-19	2009-04-23	Boehringer Ingelheim International Gmbh	New piperazino-dihydrothienopyrimidine derivatives
CN104069112A (zh) *	2007-10-19	2014-10-01	贝林格尔.英格海姆国际有限公司	取代的哌啶子基-二氢噻吩并嘧啶
GB0721095D0 (en) *	2007-10-26	2007-12-05	Piramed Ltd	Pharmaceutical compounds
EP2451811A1 (en) *	2009-05-27	2012-05-16	F. Hoffmann-La Roche AG	Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
SG175708A1 (en) *	2009-05-27	2011-12-29	Genentech Inc	Bicyclic pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
NZ599939A (en) *	2009-10-12	2014-02-28	Hoffmann La Roche	Combinations of a pi3k inhibitor and a mek inhibitor
US9802954B2 (en)	2011-08-24	2017-10-31	Boehringer Ingelheim International Gmbh	Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
US20130059866A1 (en)	2011-08-24	2013-03-07	Boehringer Ingelheim International Gmbh	Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma

0
- BE BE754606D patent/BE754606A/xx unknown
1970
- 1970-07-21 BG BG015244A patent/BG17591A3/xx unknown
- 1970-08-04 US US00060933A patent/US3838121A/en not_active Expired - Lifetime
- 1970-08-04 PH PH11712*UA patent/PH9574A/en unknown
- 1970-08-05 NL NL7011592A patent/NL7011592A/xx unknown
- 1970-08-06 SE SE7010832A patent/SE386449B/xx unknown
- 1970-08-06 CH CH340873A patent/CH547300A/xx not_active IP Right Cessation
- 1970-08-06 FI FI702170A patent/FI51939C/fi active
- 1970-08-06 CH CH1185070A patent/CH547299A/xx not_active IP Right Cessation
- 1970-08-06 CH CH341173A patent/CH547304A/xx not_active IP Right Cessation
- 1970-08-06 CH CH340973A patent/CH547301A/xx not_active IP Right Cessation
- 1970-08-06 CH CH341073A patent/CH546251A/xx not_active IP Right Cessation
- 1970-08-07 IL IL35078A patent/IL35078A/xx unknown
- 1970-08-07 ES ES382550A patent/ES382550A1/es not_active Expired
- 1970-08-07 ES ES382551A patent/ES382551A1/es not_active Expired
- 1970-08-07 ES ES382548A patent/ES382548A1/es not_active Expired
- 1970-08-07 ES ES382552A patent/ES382552A1/es not_active Expired
- 1970-08-07 ES ES382549A patent/ES382549A1/es not_active Expired
- 1970-08-07 FR FR7029316A patent/FR2068478B1/fr not_active Expired
- 1970-08-07 NO NO3045/70A patent/NO130538C/no unknown
- 1970-08-07 IE IE1025/70A patent/IE34687B1/xx unknown
- 1970-08-08 JP JP45069666A patent/JPS519759B1/ja active Pending

Also Published As

Publication number	Publication date
IL35078A (en)	1974-09-10
US3838121A (en)	1974-09-24
FI51939B (es)	1977-01-31
CH547300A (de)	1974-03-29
IE34687L (en)	1971-02-08
ES382550A1 (es)	1973-04-16
FR2068478A1 (es)	1971-08-27
NL7011592A (es)	1971-02-10
NO130538C (es)	1975-01-08
CH547304A (de)	1974-03-29
BE754606A (fr)	1971-02-08
PH9574A (en)	1976-01-16
NO130538B (es)	1974-09-23
FR2068478B1 (es)	1974-08-30
ES382552A1 (es)	1973-04-16
ES382551A1 (es)	1973-04-01
CH546251A (de)	1974-02-28
IL35078A0 (en)	1970-10-30
JPS519759B1 (es)	1976-03-30
BG17591A3 (bg)	1973-11-10
CH547301A (de)	1974-03-29
ES382548A1 (es)	1973-04-01
IE34687B1 (en)	1975-07-23
FI51939C (fi)	1977-05-10
SE386449B (sv)	1976-08-09
CH547299A (de)	1974-03-29

Publication	Publication Date	Title
ES382548A1 (es)	1973-04-01	Un procedimiento para la preparacion de nuevas 2-amino-al- cohil-amino-tieno (3,2-d)piridinas.
ES387553A1 (es)	1974-01-16	Procedimiento para la preparacion de 4-morfolino-tieno (3,-2-d)-pirimidinas.
ES425626A1 (es)	1976-06-16	Un procedimiento para preparar compuestos de acil-xilidida.
ES419936A1 (es)	1976-05-01	Procedimiento para la preparacion de sulfamidas.
ES401590A1 (es)	1975-02-16	Procedimiento para la preparacion de nuevas pirido (3,2-d) pirimidinas.
ES321531A1 (es)	1966-11-01	Procedimiento para la fabricacion de nuevas 7-(picolilaminoalquilteofilinas).
ES397308A1 (es)	1974-05-16	Un procedimiento para preparar esteres del acido mandeloil - aminocefalosporanico.
ES428818A1 (es)	1976-08-16	Procedimiento para la preparacion de 1-amino-3-fenoxi-pro- panoles-(2) sustituidos en n.
ES417471A1 (es)	1976-03-01	Procedimiento para la preparacion de derivados de n(6)-a- ralcohil-adenosina acilados.
ES385774A1 (es)	1973-11-16	Procedimiento para la preparacion de nuevas 2-(5-nitro-2- furil)-tieno (3,2-d) pirimidinas.
ES394972A1 (es)	1974-03-16	Procedimiento para la preparacion de nuevos 3 - alcohil - ariloximetilisoxazoles.
ES465346A1 (es)	1978-09-16	Procedimiento para preparar imidazoles 4,5-disustituidos.
ES432225A1 (es)	1976-11-01	Procedimiento de preparacion de nuevos compuestos de sulfe-namida.
ES274907A1 (es)	1962-10-01	Procedimiento para la preparaciën de nuevos derivados de iminodibencilo
ES392288A1 (es)	1973-10-01	Procedimiento para la preparacion de derivados de nitrofu- rilamidina.
ES8102111A1 (es)	1981-01-16	Procedimiento para la preparacion de n-dialcohilaminome- til-s,s-diarilsulfoximidas
ES402471A1 (es)	1976-01-01	Un procedimiento para la preparacion de derivados de 1-ari-loxi-3-amino-propanol.
ES297718A1 (es)	1964-09-01	Procedimiento para la preparación de nuevos derivados de imidazol
ES272786A1 (es)	1962-06-01	Procedimiento para la fabricacion de nuevos derivados de piperidina y sus sales
ES446321A1 (es)	1977-10-01	Un procedimiento para la preparacion de un nuevo derivado deteofilinilo.
GB999396A (en)	1965-07-28	Process for the manufacture of ethers of the yohimbane series
ES433421A1 (es)	1976-11-01	Procedimiento de obtencion de acidos 2-(anilin) nicotinicosa partir de 2-cloronicotinonitrilo.
ES316159A1 (es)	1966-04-16	Procedimiento para la preparacion de derivados del acido gamma-butirico
ES406417A1 (es)	1975-07-01	Procedimiento para la preparacion de alcohilteofilinas.
ES391805A1 (es)	1973-06-16	Un procedimiento para preparar un compuesto de purina.