ES390398A1 - A PROCEDURE FOR THE PRODUCTION OF 2- (4-THIAZOLIL) BENZYMIDAZOLES. - Google Patents

A PROCEDURE FOR THE PRODUCTION OF 2- (4-THIAZOLIL) BENZYMIDAZOLES.

Info

Publication number
ES390398A1
ES390398A1 ES390398A ES390398A ES390398A1 ES 390398 A1 ES390398 A1 ES 390398A1 ES 390398 A ES390398 A ES 390398A ES 390398 A ES390398 A ES 390398A ES 390398 A1 ES390398 A1 ES 390398A1
Authority
ES
Spain
Prior art keywords
procedure
production
formula
benzymidazoles
thiazolil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES390398A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES390398A1 publication Critical patent/ES390398A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/10—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

A procedure for the production of 2- (4-thiazolyl) benzimidazoles of the formula: **(See formula)** where R is selected from the group consisting of lower alkoxy, phenyl and para-fluorophenyl, the group being located (see formula) in position 5 (6) of the molecule, the procedure of which is to react a benzimidazole of formula: **(See formula)** where R is the one defined above and R1 is acetyl with methylamine and an excess of sulfur, at a temperature comprised between about 250º and 500ºC. (Machine-translation by Google Translate, not legally binding)
ES390398A 1968-06-27 1971-04-20 A PROCEDURE FOR THE PRODUCTION OF 2- (4-THIAZOLIL) BENZYMIDAZOLES. Expired ES390398A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA23741 1968-06-27

Publications (1)

Publication Number Publication Date
ES390398A1 true ES390398A1 (en) 1973-06-01

Family

ID=4084326

Family Applications (3)

Application Number Title Priority Date Filing Date
ES368716A Expired ES368716A1 (en) 1968-06-27 1969-06-24 A PROCEDURE FOR THE PRODUCTION OF 2- (4-THIAZOLIL) BENZYMIDAZOLES.
ES390396A Expired ES390396A1 (en) 1968-06-27 1971-04-20 A procedure for the production of 2- (4-tiazolil) benzymidazoles. (Machine-translation by Google Translate, not legally binding)
ES390398A Expired ES390398A1 (en) 1968-06-27 1971-04-20 A PROCEDURE FOR THE PRODUCTION OF 2- (4-THIAZOLIL) BENZYMIDAZOLES.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES368716A Expired ES368716A1 (en) 1968-06-27 1969-06-24 A PROCEDURE FOR THE PRODUCTION OF 2- (4-THIAZOLIL) BENZYMIDAZOLES.
ES390396A Expired ES390396A1 (en) 1968-06-27 1971-04-20 A procedure for the production of 2- (4-tiazolil) benzymidazoles. (Machine-translation by Google Translate, not legally binding)

Country Status (10)

Country Link
AT (1) AT291992B (en)
BR (1) BR6910199D0 (en)
CH (1) CH521985A (en)
DK (1) DK130530B (en)
ES (3) ES368716A1 (en)
FR (1) FR2014309A1 (en)
NL (1) NL6909078A (en)
PL (1) PL80109B1 (en)
SE (1) SE343862B (en)
YU (1) YU32808B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3131535B1 (en) 2022-01-01 2025-03-07 Formule&Sens Cosmetic composition comprising a wax of vegetable origin, an oil or butter of vegetable origin, an N acyl amino acid salt, a particular water-insoluble powder and a particular polyol.

Also Published As

Publication number Publication date
AT291992B (en) 1971-08-10
DK130530B (en) 1975-03-03
PL80109B1 (en) 1975-08-30
CH521985A (en) 1972-04-30
YU155569A (en) 1974-12-31
BR6910199D0 (en) 1973-02-08
SE343862B (en) 1972-03-20
DK130530C (en) 1975-08-04
FR2014309A1 (en) 1970-04-17
ES368716A1 (en) 1971-10-16
YU32808B (en) 1975-08-31
NL6909078A (en) 1969-12-30
ES390396A1 (en) 1973-06-01

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