ES403373A2 - Procedure for the preparation of N- (furil-methyl) morphinanes. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of N- (furil-methyl) morphinanes. (Machine-translation by Google Translate, not legally binding)

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Publication number
ES403373A2
ES403373A2 ES403373A ES403373A ES403373A2 ES 403373 A2 ES403373 A2 ES 403373A2 ES 403373 A ES403373 A ES 403373A ES 403373 A ES403373 A ES 403373A ES 403373 A2 ES403373 A2 ES 403373A2
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ES
Spain
Prior art keywords
formula
methyl
hydrogen atom
signifies
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES403373A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
C.H. Boehringer Sohn AG and Co KG
Original Assignee
C.H. Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H. Boehringer Sohn AG and Co KG filed Critical C.H. Boehringer Sohn AG and Co KG
Priority to ES403373A priority Critical patent/ES403373A2/en
Publication of ES403373A2 publication Critical patent/ES403373A2/en
Expired legal-status Critical Current

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Abstract

Improvements introduced in the object of the main patent No. 399,875, applied for on February 17, 1972, for: "Procedure for the preparation of N- (furyl-methyl) -morphonanes" of the general formula **(See formula)** wherein R signifies a hydrogen atom or a methyl or acetyl group and R1 signifies a hydrogen atom or a methyl or ethyl group, and of their acid addition salts, characterized in that a morphinan of the formula is reacted **(See formula)** wherein R'means a hydrogen atom, an alcohol, aralcohyl or acyl group, with a quaternary ammonium salt of the formula **(See formula)** wherein Z signifies a hydrogen atom, a methyl or ethyl group, or a substituent that can be transformed by chemical reaction into a hydrogen atom or a methyl or ethyl group, and A signifies the anion of an organic or inorganic acid, to form a compound of the formula **(See formula)** in which R'and Z have the meanings mentioned above; and if compounds of formula IV are obtained, in which Z does not have the meaning of R1-the substituent Z is transformed by chemical reaction into a hydrogen atom or a methyl or ethyl group; and if desired - for the preparation of a compound of the formula I, in which R signifies a hydrogen atom, a compound of the formula is dealkoxylated or deacylated **(See formula)** where R1 has the meanings mentioned above and R'means an alcoholic, aralcohyl or acyl group; and if desired - for the preparation of a compound of the formula I, in which R means a methyl or acetyl group - a compound of the formula IVa is methylated or acetylated, in which R1 has the aforementioned meanings and R' designates a hydrogen atom, and eventually the compounds of the general formula I are transformed into their physiologically harmless acid addition salts. (Machine-translation by Google Translate, not legally binding)
ES403373A 1972-05-31 1972-05-31 Procedure for the preparation of N- (furil-methyl) morphinanes. (Machine-translation by Google Translate, not legally binding) Expired ES403373A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES403373A ES403373A2 (en) 1972-05-31 1972-05-31 Procedure for the preparation of N- (furil-methyl) morphinanes. (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES403373A ES403373A2 (en) 1972-05-31 1972-05-31 Procedure for the preparation of N- (furil-methyl) morphinanes. (Machine-translation by Google Translate, not legally binding)

Publications (1)

Publication Number Publication Date
ES403373A2 true ES403373A2 (en) 1977-06-16

Family

ID=8461315

Family Applications (1)

Application Number Title Priority Date Filing Date
ES403373A Expired ES403373A2 (en) 1972-05-31 1972-05-31 Procedure for the preparation of N- (furil-methyl) morphinanes. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES403373A2 (en)

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