ES406725A1 - Un procedimiento para preparar una 2,4-diamino - 5 - ben- cilpirimidina sustituida. - Google Patents
Un procedimiento para preparar una 2,4-diamino - 5 - ben- cilpirimidina sustituida.Info
- Publication number
- ES406725A1 ES406725A1 ES406725A ES406725A ES406725A1 ES 406725 A1 ES406725 A1 ES 406725A1 ES 406725 A ES406725 A ES 406725A ES 406725 A ES406725 A ES 406725A ES 406725 A1 ES406725 A1 ES 406725A1
- Authority
- ES
- Spain
- Prior art keywords
- diamino
- translation
- preparing
- machine
- legally binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title 1
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- XHPZVBGIPQQTQW-UHFFFAOYSA-N 5-benzylpyrimidine-2,4-diamine Chemical class NC1=NC(N)=NC=C1CC1=CC=CC=C1 XHPZVBGIPQQTQW-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 abstract 1
- 125000003158 alcohol group Chemical group 0.000 abstract 1
- 125000003368 amide group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- -1 methoxy, ethoxy, n-propoxy, t-butoxy Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2517169 | 1969-05-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES406725A1 true ES406725A1 (es) | 1975-10-01 |
Family
ID=10223379
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES379700A Expired ES379700A1 (es) | 1969-05-16 | 1970-05-14 | Un procedimiento para preparar derivados de nitrilo beta-a-mino-alfa-bencilacrilico. |
| ES406725A Expired ES406725A1 (es) | 1969-05-16 | 1972-09-15 | Un procedimiento para preparar una 2,4-diamino - 5 - ben- cilpirimidina sustituida. |
| ES406726A Expired ES406726A1 (es) | 1969-05-16 | 1972-09-15 | Un procedimiento para preparar dimetilsulfoxidos y dimetil-sulfonas de acido benzoico sustituido. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES379700A Expired ES379700A1 (es) | 1969-05-16 | 1970-05-14 | Un procedimiento para preparar derivados de nitrilo beta-a-mino-alfa-bencilacrilico. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES406726A Expired ES406726A1 (es) | 1969-05-16 | 1972-09-15 | Un procedimiento para preparar dimetilsulfoxidos y dimetil-sulfonas de acido benzoico sustituido. |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS505184B1 (es) |
| AT (1) | AT308082B (es) |
| BR (1) | BR6915082D0 (es) |
| CA (1) | CA994812A (es) |
| CH (1) | CH544071A (es) |
| DE (1) | DE2023977C2 (es) |
| ES (3) | ES379700A1 (es) |
| FI (1) | FI56375C (es) |
| FR (1) | FR2070070A1 (es) |
| IL (1) | IL34433A (es) |
| IT (1) | IT1021507B (es) |
| NL (2) | NL173395C (es) |
| PL (1) | PL92440B1 (es) |
| SE (2) | SE400777B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1469521A (en) * | 1973-01-05 | 1977-04-06 | Wellcome Found | Antimicrobial preparations |
| US4687861A (en) * | 1984-11-28 | 1987-08-18 | Ciba-Geigy Corporation | Microbicidal compositions |
| CN1930135B (zh) * | 2004-03-05 | 2011-12-28 | 弗·哈夫曼-拉罗切有限公司 | 作为p2x3和p2x2/3拮抗剂的二氨基嘧啶 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3049544A (en) * | 1962-08-14 | Method for the preparation of | ||
| DE1303727B (de) | 1959-09-03 | 1976-02-05 | Ausscheidung aus: 14 45 176 The Wellcome Foundation Ltd., London | Alpha-Arylidensubstituierte Propioni-Irile |
| NL122146C (es) * | 1960-09-02 | |||
| DE1620729A1 (de) | 1965-07-08 | 1970-08-20 | Wellcome Found | Verfahren zur Herstellung von substituierten Benzylpyrimidinen |
| GB1261455A (en) | 1969-03-06 | 1972-01-26 | Burroughs Wellcome Co | Improvements in or relating to substituted acrylonitriles |
-
1969
- 1969-12-12 BR BR215082/69A patent/BR6915082D0/pt unknown
-
1970
- 1970-03-05 PL PL1970177150A patent/PL92440B1/pl unknown
- 1970-03-06 AT AT100472A patent/AT308082B/de active
- 1970-05-01 IL IL34433A patent/IL34433A/xx unknown
- 1970-05-13 FI FI1338/70A patent/FI56375C/fi active
- 1970-05-14 ES ES379700A patent/ES379700A1/es not_active Expired
- 1970-05-15 FR FR7017799A patent/FR2070070A1/fr active Granted
- 1970-05-15 SE SE7006713A patent/SE400777B/xx unknown
- 1970-05-15 IT IT50715/70A patent/IT1021507B/it active
- 1970-05-15 JP JP45041540A patent/JPS505184B1/ja active Pending
- 1970-05-15 DE DE2023977A patent/DE2023977C2/de not_active Expired
- 1970-05-15 CH CH732370A patent/CH544071A/de not_active IP Right Cessation
- 1970-05-15 NL NLAANVRAGE7007108,A patent/NL173395C/xx not_active IP Right Cessation
- 1970-05-19 CA CA083,401A patent/CA994812A/en not_active Expired
-
1972
- 1972-09-15 ES ES406725A patent/ES406725A1/es not_active Expired
- 1972-09-15 ES ES406726A patent/ES406726A1/es not_active Expired
-
1973
- 1973-06-07 SE SE7308030A patent/SE398878B/xx unknown
-
1980
- 1980-08-25 NL NL8004796A patent/NL8004796A/nl not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NL7007108A (es) | 1970-11-18 |
| FR2070070A1 (en) | 1971-09-10 |
| FI56375B (fi) | 1979-09-28 |
| IL34433A (en) | 1971-10-20 |
| ES406726A1 (es) | 1975-10-01 |
| NL8004796A (nl) | 1980-11-28 |
| SE398878B (sv) | 1978-01-23 |
| BR6915082D0 (pt) | 1973-03-08 |
| NL173395B (nl) | 1983-08-16 |
| PL92440B1 (en) | 1977-04-30 |
| JPS505184B1 (es) | 1975-02-28 |
| NL173395C (nl) | 1984-01-16 |
| FR2070070B1 (es) | 1974-10-11 |
| AT308082B (de) | 1973-06-25 |
| CA994812A (en) | 1976-08-10 |
| DE2023977C2 (de) | 1984-03-15 |
| CH544071A (de) | 1973-11-15 |
| DE2023977A1 (de) | 1971-02-18 |
| IL34433A0 (en) | 1970-07-19 |
| IT1021507B (it) | 1978-02-20 |
| FI56375C (fi) | 1980-01-10 |
| SE400777B (sv) | 1978-04-10 |
| ES379700A1 (es) | 1973-01-16 |
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