ES410370A1 - Procedimiento para la obtencion de derivados de la pirrolo (3,4-b) pirazina. - Google Patents

Procedimiento para la obtencion de derivados de la pirrolo (3,4-b) pirazina.

Info

Publication number
ES410370A1
ES410370A1 ES410370A ES410370A ES410370A1 ES 410370 A1 ES410370 A1 ES 410370A1 ES 410370 A ES410370 A ES 410370A ES 410370 A ES410370 A ES 410370A ES 410370 A1 ES410370 A1 ES 410370A1
Authority
ES
Spain
Prior art keywords
substd
anticonvuls
tranquillizers
pyrazines
carbonyloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES410370A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc SA
Original Assignee
Rhone Poulenc SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc SA filed Critical Rhone Poulenc SA
Publication of ES410370A1 publication Critical patent/ES410370A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedimiento para la obtención de derivados de la pirrolo [3,4-b] pirazina de fórmula general **fórmula** en la que A representa un radical fenilo, piridilo, piridazinilo o quinolil-2,-3 o 4 estando eventualmente estos radicales sustituidos por uno o varios átomos o radicales, idénticos o diferentes, elegidos de entre los átomos de halógeno, los radicales alquilos que contienen de 1 a 4 átomos de carbono, alquiloxilo cuya parte alquilo contiene de 1 a 4 átomos de carbono, ciano y nitro, así como sus sales de adición con los ácidos, caracterizado porque se hace reaccionar la cloro carbonil-1- metil-4 piperazina sobre una sal alcalina, eventualmente preparada in situ, de un derivado de la pirrolo [3,4-b] pirazina de fórmula general **fórmula** en la que A se define como precedentemente, a continuación eventualmente se transforma el producto obtenido en una sal de adición con un ácido.
ES410370A 1972-01-07 1973-01-05 Procedimiento para la obtencion de derivados de la pirrolo (3,4-b) pirazina. Expired ES410370A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7200505A FR2166314A1 (en) 1972-01-07 1972-01-07 6-substd 5-(4-methyl 1-piperazinyl)carbonyloxy 7-oxo - 5,6-dihydro-pyrrolo (3,4-b)pyrazines - tranquillizers and anticonvuls

Publications (1)

Publication Number Publication Date
ES410370A1 true ES410370A1 (es) 1975-12-16

Family

ID=9091606

Family Applications (2)

Application Number Title Priority Date Filing Date
ES410370A Expired ES410370A1 (es) 1972-01-07 1973-01-05 Procedimiento para la obtencion de derivados de la pirrolo (3,4-b) pirazina.
ES410371A Expired ES410371A1 (es) 1972-01-07 1973-01-05 Procedimiento para la obtencion de derivados de la pirrolo (3,4-b) pirazina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES410371A Expired ES410371A1 (es) 1972-01-07 1973-01-05 Procedimiento para la obtencion de derivados de la pirrolo (3,4-b) pirazina.

Country Status (9)

Country Link
AR (1) AR195635A1 (es)
CH (2) CH564558A5 (es)
CS (2) CS180610B2 (es)
ES (2) ES410370A1 (es)
FR (1) FR2166314A1 (es)
PL (2) PL91759B1 (es)
SU (2) SU548212A3 (es)
YU (2) YU35597B (es)
ZA (1) ZA7372B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2671800B1 (fr) * 1991-01-17 1993-03-12 Rhone Poulenc Rorer Sa Derive de la 5h-pyrrolo[3,4-b]pyrazine optiquement actif, sa preparation et les compositions pharmaceutiques qui le contiennent.

Also Published As

Publication number Publication date
ES410371A1 (es) 1975-12-01
YU35888B (en) 1981-08-31
CH560702A5 (es) 1975-04-15
YU2073A (en) 1980-09-25
FR2166314B1 (es) 1975-10-31
CS180649B1 (en) 1977-08-31
PL82478B1 (en) 1975-10-31
SU504484A3 (ru) 1976-02-25
YU159579A (en) 1980-12-31
FR2166314A1 (en) 1973-08-17
PL91759B1 (en) 1977-03-31
CH564558A5 (es) 1975-07-31
SU548212A3 (ru) 1977-02-25
AR195635A1 (es) 1973-10-23
YU35597B (en) 1981-04-30
ZA7372B (en) 1973-09-26
CS180610B2 (en) 1978-01-31

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19950227