ES413695A3 - Procedure for the preparation of 17-cicloocteniloxi-esteroides. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of 17-cicloocteniloxi-esteroides. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES413695A3 ES413695A3 ES413695A ES413695A ES413695A3 ES 413695 A3 ES413695 A3 ES 413695A3 ES 413695 A ES413695 A ES 413695A ES 413695 A ES413695 A ES 413695A ES 413695 A3 ES413695 A3 ES 413695A3
- Authority
- ES
- Spain
- Prior art keywords
- betah
- alphah
- alphaoac
- formula
- translation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- IIRFCWANHMSDCG-UHFFFAOYSA-N cyclooctanone Chemical class O=C1CCCCCCC1 IIRFCWANHMSDCG-UHFFFAOYSA-N 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
Landscapes
- Steroid Compounds (AREA)
Abstract
Procedure for the preparation of 17-cyclo-octenyloxy-steroids of the formula **(See formula)** in which R1 represents an oxygen atom, alphaH (betaOH), alphaH (betaOAc), betaH (alphaOH), betaH (alphaOAc) where Ac is the radical of acetic acid; R2 represents hydrogen or methyl; represents methyl or ethyl; ring A can have one unsaturation between the carbon atoms in position 1 (2), 4 (5) or 5 (10), or two unsaturations between the carbon atoms in positions 1 (2) and 4 (5) 5; the sinuous line at position 5 indicates that the hydrogen atom, if present, can assume the alpha or beta configuration, characterized in that a functional derivative of cyclooctanone is reacted at a temperature higher than 80ºC for a period of 15 minutes after 2 hours, with a 17beta-hydroxysteroid of the formula **(See formula)** in which R1 represents an oxygen atom, alphaH (beta OAc), betaH (alphaOAc) where Ac is the radical of acetic acid, R2, R3, ring A and the sinuous line at position 5 have the aforementioned meanings and unsaturations, and because the obtained 17beta-cyclocctenyl ether, in case it represents alphaH (betaOAc) or betaH (alphaOAc), is optionally subjected to hydrolysis to obtain the desired compound. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES413695A ES413695A3 (en) | 1973-04-14 | 1973-04-14 | Procedure for the preparation of 17-cicloocteniloxi-esteroides. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES413695A ES413695A3 (en) | 1973-04-14 | 1973-04-14 | Procedure for the preparation of 17-cicloocteniloxi-esteroides. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES413695A3 true ES413695A3 (en) | 1976-01-16 |
Family
ID=8463906
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES413695A Expired ES413695A3 (en) | 1973-04-14 | 1973-04-14 | Procedure for the preparation of 17-cicloocteniloxi-esteroides. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES413695A3 (en) |
-
1973
- 1973-04-14 ES ES413695A patent/ES413695A3/en not_active Expired
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