ES414319A1 - A PROCEDURE FOR THE PREPARATION OF A PIRANONE. - Google Patents

A PROCEDURE FOR THE PREPARATION OF A PIRANONE.

Info

Publication number
ES414319A1
ES414319A1 ES414319A ES414319A ES414319A1 ES 414319 A1 ES414319 A1 ES 414319A1 ES 414319 A ES414319 A ES 414319A ES 414319 A ES414319 A ES 414319A ES 414319 A1 ES414319 A1 ES 414319A1
Authority
ES
Spain
Prior art keywords
alkyl
straight
procedure
preparation
branched chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES414319A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon Pharma UK Ltd
Merck Sharp and Dohme IA Corp
Original Assignee
Merck Sharp and Dohme Ltd
Merck Sharp and Dohme IA Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme Ltd, Merck Sharp and Dohme IA Corp filed Critical Merck Sharp and Dohme Ltd
Publication of ES414319A1 publication Critical patent/ES414319A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/40—Oxygen atoms attached in positions 3 and 4, e.g. maltol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

A procedure for the preparation of a pyranone of structure: ** (See formula) ** where an epoxide of structure is reacted with an amine of structure H2NHR1, where in each of the above structures R is selected from the group consisting of C1-3 alkyl and phenyl-C1-3 alkyl and R1 is selected from the group formed by straight or branched chain C3-6 alkyl, straight or branched chain C3-6 hydroxyalkyl, straight or branched chain C3-6 alkynyl, phenyl-C1-6alkyl and indolyl-C1-6alkyl. (Machine-translation by Google Translate, not legally binding)
ES414319A 1972-05-05 1973-05-03 A PROCEDURE FOR THE PREPARATION OF A PIRANONE. Expired ES414319A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA141,469A CA989848A (en) 1972-05-05 1972-05-05 3-(3-substituted amino-2-hydroxypropoxy)-2-substituted-4-pyranones and process for preparing

Publications (1)

Publication Number Publication Date
ES414319A1 true ES414319A1 (en) 1976-02-01

Family

ID=4093187

Family Applications (1)

Application Number Title Priority Date Filing Date
ES414319A Expired ES414319A1 (en) 1972-05-05 1973-05-03 A PROCEDURE FOR THE PREPARATION OF A PIRANONE.

Country Status (13)

Country Link
JP (1) JPS5635185B2 (en)
AU (1) AU473061B2 (en)
BE (1) BE799097A (en)
CA (1) CA989848A (en)
CH (1) CH577989A5 (en)
DE (1) DE2322361A1 (en)
ES (1) ES414319A1 (en)
FR (1) FR2183750B1 (en)
GB (1) GB1390486A (en)
HU (1) HU165584B (en)
NL (1) NL7305478A (en)
SE (1) SE396605B (en)
ZA (1) ZA733050B (en)

Also Published As

Publication number Publication date
CA989848A (en) 1976-05-25
CH577989A5 (en) 1976-07-30
NL7305478A (en) 1973-11-07
JPS5635185B2 (en) 1981-08-15
ZA733050B (en) 1974-12-24
BE799097A (en) 1973-11-05
GB1390486A (en) 1975-04-16
DE2322361A1 (en) 1973-11-22
FR2183750A1 (en) 1973-12-21
HU165584B (en) 1974-09-28
AU473061B2 (en) 1976-06-10
FR2183750B1 (en) 1976-03-05
SE396605B (en) 1977-09-26
AU5493873A (en) 1974-10-31
JPS4961167A (en) 1974-06-13

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