ES423970A1 - Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES423970A1 ES423970A1 ES423970A ES423970A ES423970A1 ES 423970 A1 ES423970 A1 ES 423970A1 ES 423970 A ES423970 A ES 423970A ES 423970 A ES423970 A ES 423970A ES 423970 A1 ES423970 A1 ES 423970A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- signifies
- carbon atoms
- group
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 2
- 125000003158 alcohol group Chemical group 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- 150000007522 mineralic acids Chemical class 0.000 abstract 2
- 150000007524 organic acids Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000003939 benzylamines Chemical class 0.000 abstract 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 1
- FNIATMYXUPOJRW-UHFFFAOYSA-N cyclohexylidene Chemical group [C]1CCCCC1 FNIATMYXUPOJRW-UHFFFAOYSA-N 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Procedure for the preparation of new benzylamines of the general formula I, **(See formula)** where Hal signifies a chlorine or bromine atom, R1 signifies a hydrogen, chlorine or bromine atom, R2 signifies the morpholinocarbonylmethyl radical, a branched alcohol radical with 3 to 5 carbon atoms, optionally substituted with 1 to 3 hydroxyl groups, or a group of the formula **(See formula)** where R3 signifies a hydroxy group or an alcohol group with 1 to 4 carbon atoms, n signifies the numbers 0, 1 or 2 and the two radicals A and B signify hydrogen atoms or together the group **(See formula)** where R5 represents a hydrogen atom or a lower alcohol radical with 1 or 2 carbon atoms and m means numbers 1 or 2, R4 a hydrogen atom and l means numbers 1 or 2, as well as their acid addition salts Physiologically compatible with organic or inorganic acids, characterized in that a compound of the general formula is reduced **(See formula)** or a compound of the general formula IIa **(See formula)** where R1, R2, Hal and l are as initially defined; Z signifies a cyclohexylidene radical optionally substituted with a hydroxy group or with an alcohol group with 1 to 4 carbon atoms, a branched alcoholicidene radical with 3 to 5 carbon atoms or the morpholinocarbonylmethylidene radical and R7 means a hydrogen atom or a radical of carboxylic acid; and a compound of the general formula I, obtained according to the procedure, is subsequently transformed, if desired, into its physiologically compatible salts with organic or inorganic acids. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19722251891 DE2251891C3 (en) | 1972-10-23 | Benzylamines, their physiologically acceptable salts, processes for their preparation and pharmaceuticals containing them | |
| DE2316325A DE2316325A1 (en) | 1972-10-23 | 1973-04-02 | Halo-hydroxy-substd-benzylamines - as secretolytic and antitussive agents |
| DE19732320967 DE2320967C3 (en) | 1973-04-26 | New benzylamines, their physiologically acceptable salts, processes for their production and pharmaceuticals containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES423970A1 true ES423970A1 (en) | 1976-07-01 |
Family
ID=27184783
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES419607A Expired ES419607A1 (en) | 1972-10-23 | 1973-10-13 | Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) |
| ES423970A Expired ES423970A1 (en) | 1972-10-23 | 1974-03-16 | Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) |
| ES432699A Expired ES432699A2 (en) | 1972-10-23 | 1974-12-07 | Procedure for the preparation of new bencilamines (Machine-translation by Google Translate, not legally binding) |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES419607A Expired ES419607A1 (en) | 1972-10-23 | 1973-10-13 | Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES432699A Expired ES432699A2 (en) | 1972-10-23 | 1974-12-07 | Procedure for the preparation of new bencilamines (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (3) | ES419607A1 (en) |
-
1973
- 1973-10-13 ES ES419607A patent/ES419607A1/en not_active Expired
-
1974
- 1974-03-16 ES ES423970A patent/ES423970A1/en not_active Expired
- 1974-12-07 ES ES432699A patent/ES432699A2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES419607A1 (en) | 1976-06-16 |
| ES432699A2 (en) | 1977-07-01 |
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