ES423976A1 - PROCEDURE FOR THE PREPARATION OF NEW BENZYLAMINES. - Google Patents
PROCEDURE FOR THE PREPARATION OF NEW BENZYLAMINES.Info
- Publication number
- ES423976A1 ES423976A1 ES423976A ES423976A ES423976A1 ES 423976 A1 ES423976 A1 ES 423976A1 ES 423976 A ES423976 A ES 423976A ES 423976 A ES423976 A ES 423976A ES 423976 A1 ES423976 A1 ES 423976A1
- Authority
- ES
- Spain
- Prior art keywords
- signifies
- group
- formula
- procedure
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 3
- 150000003939 benzylamines Chemical class 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003158 alcohol group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyrrole Compounds (AREA)
Abstract
Procedure for the preparation of new benzylamines of the general formula I, **(See formula)** where Hal signifies a chlorine or bromine atom, R1 signifies a hydrogen, chlorine or bromine atom, R2 signifies the morpholinocarbonylmethyl radical, a branched alcohol radical with 3 to 5 carbon atoms, optionally substituted with 1 to 3 hydroxyl groups, or a group of the formula **(See formula)** where R3 signifies a hydrogen atom, a hydroxy group or an alcohol group with 1 to 4 carbon atoms, n signifies the numbers 0, 1 or 2 and the two radicals A and B signify hydrogen atoms or together the group **(See formula)** where R5 represents a hydrogen atom or a lower alcohol radical with 1 or 2 carbon atoms and m means numbers 1 or 2, and 1 means numbers 1 or 2, as well as their physiologically acid-compatible acid addition salts. organic or inorganic, characterized in that a compound of the general formula II is hydrolyzed **(See formula)** where R1, R2, Hal and l are as initially defined; and A represents the group -CH2- or -CO- and a compound of the general formula I, obtained according to the procedure, is subsequently transformed, if desired, into its physiologically compatible salts with organic or inorganic acids. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2316325A DE2316325A1 (en) | 1972-10-23 | 1973-04-02 | Halo-hydroxy-substd-benzylamines - as secretolytic and antitussive agents |
| DE19732320967 DE2320967C3 (en) | 1973-04-26 | New benzylamines, their physiologically acceptable salts, processes for their production and pharmaceuticals containing them | |
| DE2346743A DE2346743C3 (en) | 1972-10-23 | 1973-09-17 | 2- or 4-Hydroxy-3,5-dihalogenobenzylamines, their physiologically tolerable salts, processes for their preparation and medicaments containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES423976A1 true ES423976A1 (en) | 1976-06-16 |
Family
ID=27185164
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES423976A Expired ES423976A1 (en) | 1973-04-02 | 1974-03-06 | PROCEDURE FOR THE PREPARATION OF NEW BENZYLAMINES. |
| ES423975A Expired ES423975A1 (en) | 1973-04-02 | 1974-03-06 | PROCEDURE FOR THE PREPARATION OF NEW BENZYLAMINES. |
| ES423974A Expired ES423974A1 (en) | 1973-04-02 | 1974-03-06 | Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) |
| ES423973A Expired ES423973A1 (en) | 1973-04-02 | 1974-03-14 | PROCEDURE FOR THE PREPARATION OF NEW BENZYLAMINES. |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES423975A Expired ES423975A1 (en) | 1973-04-02 | 1974-03-06 | PROCEDURE FOR THE PREPARATION OF NEW BENZYLAMINES. |
| ES423974A Expired ES423974A1 (en) | 1973-04-02 | 1974-03-06 | Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) |
| ES423973A Expired ES423973A1 (en) | 1973-04-02 | 1974-03-14 | PROCEDURE FOR THE PREPARATION OF NEW BENZYLAMINES. |
Country Status (5)
| Country | Link |
|---|---|
| AT (1) | ATA88775A (en) |
| ES (4) | ES423976A1 (en) |
| MX (1) | MX3141E (en) |
| PL (3) | PL91891B1 (en) |
| SU (4) | SU512696A3 (en) |
-
1973
- 1973-10-17 AT AT8877573A patent/ATA88775A/en not_active IP Right Cessation
- 1973-10-22 PL PL17667673A patent/PL91891B1/pl unknown
- 1973-10-22 PL PL17667573A patent/PL92541B1/pl unknown
- 1973-10-22 PL PL17667773A patent/PL91890B1/pl unknown
- 1973-10-23 MX MX360873U patent/MX3141E/en unknown
-
1974
- 1974-03-06 ES ES423976A patent/ES423976A1/en not_active Expired
- 1974-03-06 ES ES423975A patent/ES423975A1/en not_active Expired
- 1974-03-06 ES ES423974A patent/ES423974A1/en not_active Expired
- 1974-03-14 ES ES423973A patent/ES423973A1/en not_active Expired
- 1974-10-10 SU SU2065407A patent/SU512696A3/en active
- 1974-10-10 SU SU2065409A patent/SU515443A3/en active
- 1974-10-10 SU SU2065434A patent/SU532338A3/en active
- 1974-10-10 SU SU2065406A patent/SU533333A3/en active
Also Published As
| Publication number | Publication date |
|---|---|
| ES423974A1 (en) | 1976-06-16 |
| ATA88775A (en) | 1975-07-15 |
| PL91891B1 (en) | 1977-03-31 |
| ES423973A1 (en) | 1976-06-16 |
| MX3141E (en) | 1980-05-06 |
| SU512696A3 (en) | 1976-04-30 |
| SU533333A3 (en) | 1976-10-25 |
| SU532338A3 (en) | 1976-10-15 |
| SU515443A3 (en) | 1976-05-25 |
| ES423975A1 (en) | 1976-06-16 |
| PL91890B1 (en) | 1977-03-31 |
| PL92541B1 (en) | 1977-04-30 |
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