ES426330A1 - A procedure for the preparation of new derivatives of 1,2,3,4-tetrahidroisoquinoleina. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the preparation of new derivatives of 1,2,3,4-tetrahidroisoquinoleina. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES426330A1 ES426330A1 ES426330A ES426330A ES426330A1 ES 426330 A1 ES426330 A1 ES 426330A1 ES 426330 A ES426330 A ES 426330A ES 426330 A ES426330 A ES 426330A ES 426330 A1 ES426330 A1 ES 426330A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- translation
- procedure
- preparation
- machine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 3
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical group [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- -1 alkyl radical Chemical class 0.000 abstract 2
- 125000001188 haloalkyl group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 125000006239 protecting group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical group O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- UWYZHKAOTLEWKK-UHFFFAOYSA-N 1,2,3,4-tetrahydroisoquinoline Chemical class C1=CC=C2CNCCC2=C1 UWYZHKAOTLEWKK-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 229910052717 sulfur Chemical group 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A procedure for the preparation of new derivatives of 1, 2, 3, 4-tetrahydroisoquinoline of general formula; **(See formula)** where R1 and R2 are each a hydrogen atom or a lower alkyl radical, X is an oxygen or sulfur atom and R3 is a phenyl radical with one to three substituents selected from the group consisting of a lower alkoxy, hydroxy, amino radical, nitro or lower haloalkyl and a halogen atom and pharmaceutically acceptable salts thereof, the process of which is characterized by removing the protecting groups of a compound of formula; **(See formula)** where R1 and R2 are as defined above, R8 and R9 are, individually or in combination with each other, hydroxy radical protecting groups and R7 is a phenyl radical with one to three substituents selected from the group consisting of a lower alkoxy, hydroxy radical which can be protected with a protecting group, amino, nitro or lower haloalkyl and a halogen atom, or a salt thereof. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12719870A JPS4811714B1 (en) | 1970-12-29 | 1970-12-29 | |
| JP12720170A JPS4811716B1 (en) | 1970-12-29 | 1970-12-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES426330A1 true ES426330A1 (en) | 1976-07-01 |
Family
ID=26463211
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES426330A Expired ES426330A1 (en) | 1970-12-29 | 1974-05-14 | A procedure for the preparation of new derivatives of 1,2,3,4-tetrahidroisoquinoleina. (Machine-translation by Google Translate, not legally binding) |
Country Status (4)
| Country | Link |
|---|---|
| AR (2) | AR205783A1 (en) |
| AT (1) | AT319247B (en) |
| CH (1) | CH570983A5 (en) |
| ES (1) | ES426330A1 (en) |
-
1971
- 1971-12-28 AT AT06293/73A patent/AT319247B/en not_active IP Right Cessation
- 1971-12-29 CH CH757675A patent/CH570983A5/en not_active IP Right Cessation
-
1972
- 1972-01-01 AR AR244269A patent/AR205783A1/en active
-
1974
- 1974-05-14 ES ES426330A patent/ES426330A1/en not_active Expired
- 1974-06-05 AR AR254073A patent/AR203482A1/en active
Also Published As
| Publication number | Publication date |
|---|---|
| CH570983A5 (en) | 1975-12-31 |
| AR203482A1 (en) | 1975-09-15 |
| AT319247B (en) | 1974-12-10 |
| AR205783A1 (en) | 1976-06-07 |
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