ES427164A1 - Un procedimiento para la preparacion de un agente para la anastesia espinal. - Google Patents
Un procedimiento para la preparacion de un agente para la anastesia espinal.Info
- Publication number
- ES427164A1 ES427164A1 ES427164A ES427164A ES427164A1 ES 427164 A1 ES427164 A1 ES 427164A1 ES 427164 A ES427164 A ES 427164A ES 427164 A ES427164 A ES 427164A ES 427164 A1 ES427164 A1 ES 427164A1
- Authority
- ES
- Spain
- Prior art keywords
- desoxytetrodotoxin
- tetrodotoxin
- small amounts
- spinal anesthesia
- micrograms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- COVOMQKTVSVWBZ-CJCGOCGYSA-N deoxytetrodotoxin Chemical compound O1C(C2(O)CO)(O)OC3C(O)C1[C@@H]1CN=C(N)NC12C3O COVOMQKTVSVWBZ-CJCGOCGYSA-N 0.000 title abstract 3
- CFMYXEVWODSLAX-QOZOJKKESA-N tetrodotoxin Chemical compound O([C@@]([C@H]1O)(O)O[C@H]2[C@@]3(O)CO)[C@H]3[C@@H](O)[C@]11[C@H]2[C@@H](O)N=C(N)N1 CFMYXEVWODSLAX-QOZOJKKESA-N 0.000 title abstract 3
- 229950010357 tetrodotoxin Drugs 0.000 title abstract 3
- CFMYXEVWODSLAX-UHFFFAOYSA-N tetrodotoxin Natural products C12C(O)NC(=N)NC2(C2O)C(O)C3C(CO)(O)C1OC2(O)O3 CFMYXEVWODSLAX-UHFFFAOYSA-N 0.000 title abstract 3
- 238000002693 spinal anesthesia Methods 0.000 title 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0085—Brain, e.g. brain implants; Spinal cord
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US388147A US3898339A (en) | 1973-08-14 | 1973-08-14 | Spinal anesthesia using small amounts of tetrodotoxin or desoxytetrodotoxin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES427164A1 true ES427164A1 (es) | 1976-10-01 |
Family
ID=23532901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES427164A Expired ES427164A1 (es) | 1973-08-14 | 1974-06-11 | Un procedimiento para la preparacion de un agente para la anastesia espinal. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US3898339A (fr) |
| JP (1) | JPS5048112A (fr) |
| AT (1) | AT335616B (fr) |
| BE (1) | BE816214A (fr) |
| CA (1) | CA1027863A (fr) |
| DD (1) | DD115035A5 (fr) |
| DE (1) | DE2427732A1 (fr) |
| ES (1) | ES427164A1 (fr) |
| FR (1) | FR2240735B1 (fr) |
| GB (1) | GB1453343A (fr) |
| IE (1) | IE39410B1 (fr) |
| LU (1) | LU70304A1 (fr) |
| NL (1) | NL7407853A (fr) |
| ZA (1) | ZA743765B (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1051706C (zh) * | 1994-03-17 | 2000-04-26 | 南宁枫叶药业有限公司 | 氨基氢化喹唑啉类化合物及其衍生物戒降药物依赖性的新用途 |
| US5846975A (en) * | 1994-03-17 | 1998-12-08 | Nanning Maple Leaf Pharmaceutical Co., Ltd. | Use of amino hydrogenated quinazoline compounds and derivatives thereof for abstaining from drug dependence |
| US5585398A (en) * | 1994-07-15 | 1996-12-17 | Ernst; Amy A. | Topical anesthetic comprising lidocaine, adrenaline, and tetracaine, and its method of use |
| US5550049A (en) * | 1994-11-10 | 1996-08-27 | Merck & Co., Inc | Process for identifying para cation channel modulators |
| WO1998043619A2 (fr) * | 1997-04-02 | 1998-10-08 | The Regents Of The University Of California | Procede d'anesthesie |
| CN1236773C (zh) * | 2000-11-22 | 2006-01-18 | 南宁枫叶药业有限公司 | 用于镇痛、麻醉或治疗药物依赖性的制剂 |
| WO2006032459A1 (fr) * | 2004-09-22 | 2006-03-30 | Laboratorios Del Dr. Esteve S.A. | Tétrodotoxine et ses dérivés dans le traitement de la douleur neuropathique d’origine nerveuse périphérique |
| WO2007025213A2 (fr) * | 2005-08-25 | 2007-03-01 | Wex Pharmaceuticals, Inc. | Utilisation de bloqueurs des canaux sodiques pour gerer les douleurs musculo-squelettiques |
| US9018222B2 (en) * | 2006-03-27 | 2015-04-28 | Wex Medical Limited | Use of sodium channel blockers for the treatment of neuropathic pain developing as a consequence of chemotherapy |
-
1973
- 1973-08-14 US US388147A patent/US3898339A/en not_active Expired - Lifetime
-
1974
- 1974-06-08 DE DE19742427732 patent/DE2427732A1/de active Pending
- 1974-06-10 IE IE1211/74A patent/IE39410B1/xx unknown
- 1974-06-11 FR FR7420219A patent/FR2240735B1/fr not_active Expired
- 1974-06-11 ES ES427164A patent/ES427164A1/es not_active Expired
- 1974-06-12 ZA ZA00743765A patent/ZA743765B/xx unknown
- 1974-06-12 JP JP49067020A patent/JPS5048112A/ja active Pending
- 1974-06-12 DD DD179117A patent/DD115035A5/xx unknown
- 1974-06-12 CA CA202,294A patent/CA1027863A/fr not_active Expired
- 1974-06-12 GB GB2609474A patent/GB1453343A/en not_active Expired
- 1974-06-12 LU LU70304A patent/LU70304A1/xx unknown
- 1974-06-12 AT AT484974A patent/AT335616B/de not_active IP Right Cessation
- 1974-06-12 NL NL7407853A patent/NL7407853A/xx unknown
- 1974-06-12 BE BE145320A patent/BE816214A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB1453343A (en) | 1976-10-20 |
| NL7407853A (nl) | 1975-02-18 |
| IE39410L (en) | 1975-02-14 |
| US3898339A (en) | 1975-08-05 |
| FR2240735A1 (fr) | 1975-03-14 |
| BE816214A (fr) | 1974-12-12 |
| ZA743765B (en) | 1975-06-25 |
| DE2427732A1 (de) | 1975-02-27 |
| ATA484974A (de) | 1976-07-15 |
| CA1027863A (fr) | 1978-03-14 |
| FR2240735B1 (fr) | 1978-07-28 |
| IE39410B1 (en) | 1978-09-27 |
| LU70304A1 (fr) | 1976-04-13 |
| JPS5048112A (fr) | 1975-04-30 |
| DD115035A5 (fr) | 1975-09-12 |
| AT335616B (de) | 1977-03-25 |
| AU6993474A (en) | 1975-12-11 |
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