ES435761A1 - Procedimiento de analisis radioisotopico competitivo para medir la concentracion de folato en el suero. - Google Patents

Procedimiento de analisis radioisotopico competitivo para medir la concentracion de folato en el suero.

Info

Publication number: ES435761A1
Authority: ES; Spain
Prior art keywords: folate; binder; predetermined amount; labeled; radioisotopic assay
Prior art date: 1974-03-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES435761A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Case Western Reserve University

Original Assignee

Case Western Reserve University

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-03-18

Filing date

1975-03-18

Publication date

1977-03-16

1975-03-18 Application filed by Case Western Reserve University filed Critical Case Western Reserve University

1977-03-16 Publication of ES435761A1 publication Critical patent/ES435761A1/es

Status Expired legal-status Critical Current

Links

239000011230 binding agent Substances 0.000 title abstract 4
238000003556 assay Methods 0.000 title abstract 2
235000019152 folic acid Nutrition 0.000 abstract 8
229940014144 folate Drugs 0.000 abstract 7
OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 abstract 7
239000011724 folic acid Substances 0.000 abstract 7
238000000034 method Methods 0.000 abstract 2
210000002966 serum Anatomy 0.000 abstract 2
229940105150 5-methyltetrahydrofolic acid Drugs 0.000 abstract 1
150000002224 folic acids Chemical class 0.000 abstract 1
210000003734 kidney Anatomy 0.000 abstract 1
ZNOVTXRBGFNYRX-ABLWVSNPSA-N levomefolic acid Chemical compound C1NC=2NC(N)=NC(=O)C=2N(C)C1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 ZNOVTXRBGFNYRX-ABLWVSNPSA-N 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
- C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21H—OBTAINING ENERGY FROM RADIOACTIVE SOURCES; APPLICATIONS OF RADIATION FROM RADIOACTIVE SOURCES, NOT OTHERWISE PROVIDED FOR; UTILISING COSMIC RADIATION
- G21H5/00—Applications of radiation from radioactive sources or arrangements therefor, not otherwise provided for
- G21H5/02—Applications of radiation from radioactive sources or arrangements therefor, not otherwise provided for as tracers

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Physics & Mathematics (AREA)
Cell Biology (AREA)
High Energy & Nuclear Physics (AREA)
Microbiology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Investigating Or Analysing Biological Materials (AREA)

ES435761A 1974-03-18 1975-03-18 Procedimiento de analisis radioisotopico competitivo para medir la concentracion de folato en el suero. Expired ES435761A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/451,875 US3972991A (en)	1974-03-18	1974-03-18	Radioisotopic assay and binder therefor

Publications (1)

Publication Number	Publication Date
ES435761A1 true ES435761A1 (es)	1977-03-16

Family

ID=23794064

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES435761A Expired ES435761A1 (es)	1974-03-18	1975-03-18	Procedimiento de analisis radioisotopico competitivo para medir la concentracion de folato en el suero.

Country Status (5)

Country	Link
US (1)	US3972991A (es)
AR (1)	AR205738A1 (es)
BE (1)	BE826747A (es)
CA (1)	CA1022072A (es)
ES (1)	ES435761A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4146602A (en) *	1977-01-27	1979-03-27	Becton, Dickinson & Company	Simultaneous radioassay of folate and vitamin B12
US4136159A (en) *	1977-02-28	1979-01-23	New England Nuclear Corporation	Radioassay of folates
US4423154A (en) *	1978-06-26	1983-12-27	Becton Dickinson And Company	Simultaneous radioassay of folate and vitamin B12
US4337339A (en) *	1979-04-30	1982-06-29	Baker Instruments Corp.	Process for preparation of folic acid derivatives
US4298735A (en) *	1979-04-30	1981-11-03	Union Carbide Corporation	Folic acid derivatives
GB2056459B (en) *	1979-07-04	1983-03-09	Daiichi Radioisotope Lab	Pterin derivatives and an assay method for determining pterins
US4314988A (en) *	1979-10-31	1982-02-09	Baker Instruments Corp.	Folic acid derivatives and process for preparation
US4393040A (en) *	1981-03-24	1983-07-12	Lopapa Institute, Inc.	In-vitro diagnostic method for detection of acetylsalicylic acid ingestion
US4418151A (en) *	1981-03-30	1983-11-29	Rohm And Haas Company	Assay process with non-boiling denaturation
US4350659A (en) *	1981-07-30	1982-09-21	Corning Glass Works	Stabilization of sensitive biologically active intermediate metabolites such as folic acid derivatives
DE19713088C1 (de) *	1997-03-27	1998-11-26	Reiner Dr Probst	Verfahren und Blutabnahmegefäß zur Aufbereitung von Blutproben für die Homocystein- und/oder Folatbestimmung

1974
- 1974-03-18 US US05/451,875 patent/US3972991A/en not_active Expired - Lifetime
1975
- 1975-01-01 AR AR257856A patent/AR205738A1/es active
- 1975-02-10 CA CA219,674A patent/CA1022072A/en not_active Expired
- 1975-03-17 BE BE154382A patent/BE826747A/xx unknown
- 1975-03-18 ES ES435761A patent/ES435761A1/es not_active Expired

Also Published As

Publication number	Publication date
AR205738A1 (es)	1976-05-31
BE826747A (fr)	1975-07-16
AU7904175A (en)	1976-09-16
CA1022072A (en)	1977-12-06
US3972991A (en)	1976-08-03

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