ES437966A2 - Fused pyrimidine-4-(3h)-ones and preparation thereof - Google Patents
Fused pyrimidine-4-(3h)-ones and preparation thereofInfo
- Publication number
- ES437966A2 ES437966A2 ES437966A ES437966A ES437966A2 ES 437966 A2 ES437966 A2 ES 437966A2 ES 437966 A ES437966 A ES 437966A ES 437966 A ES437966 A ES 437966A ES 437966 A2 ES437966 A2 ES 437966A2
- Authority
- ES
- Spain
- Prior art keywords
- group
- hydrogen
- alkyl
- preparation
- hydroxyamino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
- C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Improvements introduced in the object of the main patent No. 425,238 applied for on April 10, 1974 for: "A process for the preparation of a pyrimidin-4- (3H) -one", specifically molten pyrimidines where it is prepared by a method known to be for analogous compounds, a compound of the formulas: **(See formula)** and the pharmaceutically acceptable cationic salts thereof, wherein R is selected from the group consisting of methyl, ethyl, acetyl and COR ° where R ° is selected from the group consisting of hydroxy, alkoxy, hydroxyalkoxy, amino and hydroxyamino; Y is selected from the group consisting of (a) hydrogen and (h) alkyl, carbalkoxyalkyl, carboxyalkyl, - (CH2) m-O-CO-C5H6 and - (CH2) m-O-alconoyl; with the proviso that curd R is methyl or ethyl, Y is selected from group (b); and when R is COR ° where R ° is amino or hydroxyamino, Y is hydrogen; it is an integer from 2 to 4; R1 is selected from the group consisting of hydrogen, alkyl, and phenyl; R2, R3, R4 and R5 are each selected from the groups consisting of (a) hydrogen, alkyl, alkoxy, halo, benoyloxy, methylthio and methylsulfinyl; and (b) hydroxy, thiol, alkanoyloxy, benzylthio, benzoyloxy, and benzylsulfonyl. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/485,945 US3974161A (en) | 1974-02-20 | 1974-07-05 | Fused pyrimidin-4(3H)-ones as antiallergy agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES437966A2 true ES437966A2 (en) | 1977-02-16 |
Family
ID=23930024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES437966A Expired ES437966A2 (en) | 1974-07-05 | 1975-05-27 | Fused pyrimidine-4-(3h)-ones and preparation thereof |
Country Status (20)
| Country | Link |
|---|---|
| JP (1) | JPS518280A (en) |
| AR (1) | AR214389A1 (en) |
| AT (1) | AT351546B (en) |
| BE (1) | BE829987R (en) |
| BG (1) | BG25226A3 (en) |
| CA (1) | CA1053674A (en) |
| CH (1) | CH619951A5 (en) |
| DD (1) | DD118093A6 (en) |
| DE (1) | DE2525050A1 (en) |
| DK (1) | DK250275A (en) |
| ES (1) | ES437966A2 (en) |
| FI (1) | FI59097C (en) |
| GB (1) | GB1501438A (en) |
| IE (1) | IE42746B1 (en) |
| LU (1) | LU72672A1 (en) |
| NO (1) | NO751594L (en) |
| RO (1) | RO69550A (en) |
| SE (1) | SE420610B (en) |
| YU (1) | YU145675A (en) |
| ZA (1) | ZA752908B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5510894U (en) * | 1979-08-03 | 1980-01-24 | ||
| JPS5510896U (en) * | 1979-08-03 | 1980-01-24 | ||
| JPS5510892U (en) * | 1979-08-03 | 1980-01-24 | ||
| JPS5510891U (en) * | 1979-08-03 | 1980-01-24 | ||
| JPS59210071A (en) * | 1982-12-30 | 1984-11-28 | バイオメジヤ−・インコ−ポレ−テツド | Antiviral compound |
| JP2006503094A (en) * | 2002-10-16 | 2006-01-26 | スミスクライン ビーチャム コーポレーション | Compound |
| WO2025143096A1 (en) * | 2023-12-29 | 2025-07-03 | キッセイ薬品工業株式会社 | Nitrogen-containing condensed ring compound |
-
1975
- 1975-04-30 CA CA225,936A patent/CA1053674A/en not_active Expired
- 1975-05-01 IE IE980/75A patent/IE42746B1/en unknown
- 1975-05-02 GB GB18583/75A patent/GB1501438A/en not_active Expired
- 1975-05-05 NO NO751594A patent/NO751594L/no unknown
- 1975-05-06 ZA ZA00752908A patent/ZA752908B/en unknown
- 1975-05-27 ES ES437966A patent/ES437966A2/en not_active Expired
- 1975-06-03 DE DE19752525050 patent/DE2525050A1/en not_active Ceased
- 1975-06-03 FI FI751628A patent/FI59097C/en not_active IP Right Cessation
- 1975-06-04 RO RO7582428A patent/RO69550A/en unknown
- 1975-06-04 BG BG030186A patent/BG25226A3/en unknown
- 1975-06-04 DK DK250275A patent/DK250275A/en unknown
- 1975-06-05 YU YU01456/75A patent/YU145675A/en unknown
- 1975-06-06 LU LU72672A patent/LU72672A1/xx unknown
- 1975-06-06 JP JP50068456A patent/JPS518280A/ja active Pending
- 1975-06-06 AR AR259117A patent/AR214389A1/en active
- 1975-06-06 CH CH730075A patent/CH619951A5/en not_active IP Right Cessation
- 1975-06-06 BE BE1006719A patent/BE829987R/en active
- 1975-06-06 DD DD186490A patent/DD118093A6/xx unknown
- 1975-06-06 AT AT432675A patent/AT351546B/en not_active IP Right Cessation
- 1975-06-21 SE SE7504599A patent/SE420610B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SE420610B (en) | 1981-10-19 |
| AT351546B (en) | 1979-07-25 |
| CH619951A5 (en) | 1980-10-31 |
| AR214389A1 (en) | 1979-06-15 |
| ATA432675A (en) | 1979-01-15 |
| DE2525050A1 (en) | 1976-01-22 |
| BG25226A3 (en) | 1978-08-10 |
| CA1053674A (en) | 1979-05-01 |
| NO751594L (en) | 1976-01-06 |
| GB1501438A (en) | 1978-02-15 |
| IE42746L (en) | 1976-01-05 |
| BE829987R (en) | 1975-12-08 |
| FI59097C (en) | 1981-06-10 |
| ZA752908B (en) | 1976-04-28 |
| DD118093A6 (en) | 1976-02-12 |
| AU8095575A (en) | 1976-11-11 |
| SE7504599L (en) | 1976-01-07 |
| FI59097B (en) | 1981-02-27 |
| YU145675A (en) | 1982-08-31 |
| LU72672A1 (en) | 1976-03-17 |
| FI751628A7 (en) | 1976-01-06 |
| RO69550A (en) | 1981-08-30 |
| DK250275A (en) | 1976-01-06 |
| JPS518280A (en) | 1976-01-23 |
| IE42746B1 (en) | 1980-10-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD2A | Announcement of lapse in spain |
Effective date: 20170705 |