ES445253A1 - Aromatic ethers and thioethers - Google Patents

Aromatic ethers and thioethers

Info

Publication number
ES445253A1
ES445253A1 ES445253A ES445253A ES445253A1 ES 445253 A1 ES445253 A1 ES 445253A1 ES 445253 A ES445253 A ES 445253A ES 445253 A ES445253 A ES 445253A ES 445253 A1 ES445253 A1 ES 445253A1
Authority
ES
Spain
Prior art keywords
group
formula
see
see graph
graph
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES445253A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES445253A1 publication Critical patent/ES445253A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/26—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C243/30—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
    • C07C243/32—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A procedure for the preparation of new hypolipidemic phenoxyalyl compounds, of the formula: **(See formula)** where one of the groups R2, R3 and R4 represents a group - (CH2) (see graph), R1 and the remaining groups R2, R3 and R4 are hydrogen Z is oxygen or sulfur. R5, R6 and R7 are independently hydrogen or a lower alkyl group, and or (i) (see graph) is zero, one or two and R is cyano or (ii) (see graph) is an integer from 2 to 12 and R1 is a carboxylic acid group or a non-toxic, pharmaceutically acceptable salt, ester, amide or hydrazide thereof, an alkyl group optionally substituted with one or more hydroxyl or alkoxy groups lower; a cyano, formyl, acyl, or carboxy-acyl group; with the proviso that when Z is oxygen and (see graph) is two, so R1 is not a carboxylic acid group; whose procedure consists of: (A) reacting a compound of formula: **(See formula)** with a compound of formula **(See formula)** where one of the radicals P or Q is -ZH (where Z is as defined above) or a reactive derivative thereof and the other is an easily movable group; and (B) optionally, converting an R1 group to another R1 group contained in the definitions given above, by the appropriate methods. (Machine-translation by Google Translate, not legally binding)
ES445253A 1975-02-19 1976-02-17 Aromatic ethers and thioethers Expired ES445253A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB690975A GB1476906A (en) 1975-02-19 1975-02-19 Aromatic ethers and thioethers

Publications (1)

Publication Number Publication Date
ES445253A1 true ES445253A1 (en) 1977-10-01

Family

ID=9823047

Family Applications (2)

Application Number Title Priority Date Filing Date
ES445253A Expired ES445253A1 (en) 1975-02-19 1976-02-17 Aromatic ethers and thioethers
ES458744A Expired ES458744A1 (en) 1975-02-19 1977-05-12 Aromatic ethers and thioethers

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES458744A Expired ES458744A1 (en) 1975-02-19 1977-05-12 Aromatic ethers and thioethers

Country Status (14)

Country Link
JP (1) JPS51125340A (en)
BE (1) BE838513A (en)
DE (1) DE2605399A1 (en)
DK (1) DK65376A (en)
ES (2) ES445253A1 (en)
FI (1) FI760403A7 (en)
FR (1) FR2301231A1 (en)
GB (1) GB1476906A (en)
IE (1) IE42421B1 (en)
IL (1) IL48965A0 (en)
NL (1) NL7601624A (en)
NO (1) NO760539L (en)
SE (1) SE7601456L (en)
ZA (1) ZA76799B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2642433A (en) * 1949-11-17 1953-06-16 Hoffmann La Roche Alpha-amino-alpha, alpha-diphenylacetic acid derivatives and method of preparing same
EP3309145A4 (en) * 2015-06-15 2019-01-23 Basseru Chemical Co., Ltd. COMPOSITION REPRESENTING MARINE PERIPHYTON

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3379755A (en) * 1964-06-04 1968-04-23 Merck & Co Inc Preparation of (4-alkanoylphenoxy) acetic acids by oxidation
FR2183536B1 (en) * 1972-05-09 1975-06-20 Bottu

Also Published As

Publication number Publication date
SE7601456L (en) 1976-11-11
ZA76799B (en) 1977-01-26
DK65376A (en) 1976-08-20
IL48965A0 (en) 1976-04-30
FI760403A7 (en) 1976-08-20
ES458744A1 (en) 1978-03-01
AU1126276A (en) 1977-08-25
DE2605399A1 (en) 1976-09-02
NL7601624A (en) 1976-08-23
IE42421L (en) 1976-08-19
IE42421B1 (en) 1980-07-30
NO760539L (en) 1976-08-20
JPS51125340A (en) 1976-11-01
BE838513A (en) 1976-08-12
GB1476906A (en) 1977-06-16
FR2301231A1 (en) 1976-09-17

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