ES453485A1 - Un procedimiento para la obtencion de 2, 5-dimetil-tieno (2,3-f) morfano. - Google Patents

Un procedimiento para la obtencion de 2, 5-dimetil-tieno (2,3-f) morfano.

Info

Publication number: ES453485A1
Authority: ES; Spain
Prior art keywords: dimethyl; thieno; formula; obtaining; reacted
Prior art date: 1976-11-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES453485A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Laboratorios Made SA

Original Assignee

Laboratorios Made SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-11-19

Filing date

1976-11-19

Publication date

1977-11-16

1976-11-19 Application filed by Laboratorios Made SA filed Critical Laboratorios Made SA

1976-11-19 Priority to ES453485A priority Critical patent/ES453485A1/es

1977-11-10 Priority to DE2750197A priority patent/DE2750197C3/de

1977-11-14 Priority to AR269962A priority patent/AR214761A1/es

1977-11-16 Priority to GB47719/77A priority patent/GB1574514A/en

1977-11-16 Publication of ES453485A1 publication Critical patent/ES453485A1/es

1977-11-18 Priority to FR7734751A priority patent/FR2371452A1/fr

1977-11-18 Priority to PT67297A priority patent/PT67297B/pt

1977-11-18 Priority to JP13798577A priority patent/JPS5365898A/ja

1977-11-18 Priority to BE182733A priority patent/BE860963A/xx

1977-11-18 Priority to NL7712770A priority patent/NL7712770A/xx

1977-11-18 Priority to AT828177A priority patent/AT353430B/de

Status Expired legal-status Critical Current

Links

238000000034 method Methods 0.000 title abstract 2
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 abstract 2
YOBTXORLVXZWSR-UHFFFAOYSA-M 1,4-dimethylpyridin-1-ium;iodide Chemical compound [I-].CC1=CC=[N+](C)C=C1 YOBTXORLVXZWSR-UHFFFAOYSA-M 0.000 abstract 1
BMYNFMYTOJXKLE-UHFFFAOYSA-N 3-azaniumyl-2-hydroxypropanoate Chemical compound NCC(O)C(O)=O BMYNFMYTOJXKLE-UHFFFAOYSA-N 0.000 abstract 1
CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 abstract 1
SUEXIXRFSURADT-NEWATCJESA-N CC1N[C@H]2[C@@H]3CC4=C(C[C@@]3(C=3C=C(C=CC=3C2)C)C1)SC=C4 Chemical compound CC1N[C@H]2[C@@H]3CC4=C(C[C@@]3(C=3C=C(C=CC=3C2)C)C1)SC=C4 SUEXIXRFSURADT-NEWATCJESA-N 0.000 abstract 1
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
238000010790 dilution Methods 0.000 abstract 1
239000012895 dilution Substances 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
229960005181 morphine Drugs 0.000 abstract 1
238000000746 purification Methods 0.000 abstract 1
238000010992 reflux Methods 0.000 abstract 1
-1 sodium boron tetrahydride Chemical compound 0.000 abstract 1
239000000243 solution Substances 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1
125000004853 tetrahydropyridinyl group Chemical class N1(CCCC=C1)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pain & Pain Management (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

ES453485A 1976-11-19 1976-11-19 Un procedimiento para la obtencion de 2, 5-dimetil-tieno (2,3-f) morfano. Expired ES453485A1 (es)

Priority Applications (10)

Application Number	Priority Date	Filing Date	Title
ES453485A ES453485A1 (es)	1976-11-19	1976-11-19	Un procedimiento para la obtencion de 2, 5-dimetil-tieno (2,3-f) morfano.
DE2750197A DE2750197C3 (de)	1976-11-19	1977-11-10	43,6,7,8,9-Hexahydro-5,9-methan-6,9-dimethylthieno [3,2,-d] azocin und Verfahren zu seiner Herstellung
AR269962A AR214761A1 (es)	1976-11-19	1977-11-14	Un procedimiento para la obtencion de 2,5-dimetil-tieno(2,3-f)morfano
GB47719/77A GB1574514A (en)	1976-11-19	1977-11-16	2,5-dimethyl-thieno(2,3-f)morphane and a process for obtaining it
AT828177A AT353430B (de)	1976-11-19	1977-11-18	Verfahren zur herstellung des neuen 2,5- -dimethyl-thieno(2,3-f)morphans
FR7734751A FR2371452A1 (fr)	1976-11-19	1977-11-18	Le 2,5-dimethyl-thieno(2-3-f)morphane, son procede de preparation et ses applications comme medicament
PT67297A PT67297B (en)	1976-11-19	1977-11-18	Process for the preparation of 2,5-dimethyl-tiene/2,3-f/morphane
JP13798577A JPS5365898A (en)	1976-11-19	1977-11-18	Novel 255dimethyllthien233f morphane and process for preparing same
BE182733A BE860963A (fr)	1976-11-19	1977-11-18	Le 2,5-dimethyl-thieno (2-3-f) morphane, son procede de preparation et ses applications comme medicament
NL7712770A NL7712770A (nl)	1976-11-19	1977-11-18	2,5-dimethyl-thieen-(2,3-f)-morfaan.

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ES453485A ES453485A1 (es)	1976-11-19	1976-11-19	Un procedimiento para la obtencion de 2, 5-dimetil-tieno (2,3-f) morfano.

Publications (1)

Publication Number	Publication Date
ES453485A1 true ES453485A1 (es)	1977-11-16

Family

ID=8472620

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES453485A Expired ES453485A1 (es)	1976-11-19	1976-11-19	Un procedimiento para la obtencion de 2, 5-dimetil-tieno (2,3-f) morfano.

Country Status (10)

Country	Link
JP (1)	JPS5365898A (es)
AR (1)	AR214761A1 (es)
AT (1)	AT353430B (es)
BE (1)	BE860963A (es)
DE (1)	DE2750197C3 (es)
ES (1)	ES453485A1 (es)
FR (1)	FR2371452A1 (es)
GB (1)	GB1574514A (es)
NL (1)	NL7712770A (es)
PT (1)	PT67297B (es)

1976
- 1976-11-19 ES ES453485A patent/ES453485A1/es not_active Expired
1977
- 1977-11-10 DE DE2750197A patent/DE2750197C3/de not_active Expired
- 1977-11-14 AR AR269962A patent/AR214761A1/es active
- 1977-11-16 GB GB47719/77A patent/GB1574514A/en not_active Expired
- 1977-11-18 BE BE182733A patent/BE860963A/xx unknown
- 1977-11-18 NL NL7712770A patent/NL7712770A/xx not_active Application Discontinuation
- 1977-11-18 AT AT828177A patent/AT353430B/de not_active IP Right Cessation
- 1977-11-18 FR FR7734751A patent/FR2371452A1/fr not_active Withdrawn
- 1977-11-18 PT PT67297A patent/PT67297B/pt unknown
- 1977-11-18 JP JP13798577A patent/JPS5365898A/ja active Pending

Also Published As

Publication number	Publication date
GB1574514A (en)	1980-09-10
PT67297B (en)	1979-04-20
DE2750197C3 (de)	1980-09-18
DE2750197A1 (de)	1978-05-24
DE2750197B2 (de)	1980-01-24
NL7712770A (nl)	1978-05-23
ATA828177A (de)	1979-04-15
FR2371452A1 (fr)	1978-06-16
BE860963A (fr)	1978-03-16
AR214761A1 (es)	1979-07-31
JPS5365898A (en)	1978-06-12
PT67297A (en)	1977-12-01
AT353430B (de)	1979-11-12

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Legal Events

Date	Code	Title	Description
1999-01-01	FD1A	Patent lapsed	Effective date: 19981103