ES455365A1 - Un metodo de preparacion de un peptido dotado de actividad biologica analoga a la de la morfina. - Google Patents

Un metodo de preparacion de un peptido dotado de actividad biologica analoga a la de la morfina.

Info

Publication number
ES455365A1
ES455365A1 ES455365A ES455365A ES455365A1 ES 455365 A1 ES455365 A1 ES 455365A1 ES 455365 A ES455365 A ES 455365A ES 455365 A ES455365 A ES 455365A ES 455365 A1 ES455365 A1 ES 455365A1
Authority
ES
Spain
Prior art keywords
peptide
radical
formula
derivatives
dialkylamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES455365A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB2900/76A external-priority patent/GB1577114A/en
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of ES455365A1 publication Critical patent/ES455365A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1016Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/70Enkephalins
    • C07K14/702Enkephalins with at least 1 amino acid in D-form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ES455365A 1976-01-26 1977-01-26 Un metodo de preparacion de un peptido dotado de actividad biologica analoga a la de la morfina. Expired ES455365A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2900/76A GB1577114A (en) 1976-01-26 1976-01-26 Biologically active peptides
GB848176 1976-03-03
GB4882176 1976-11-23

Publications (1)

Publication Number Publication Date
ES455365A1 true ES455365A1 (es) 1978-05-16

Family

ID=27254145

Family Applications (1)

Application Number Title Priority Date Filing Date
ES455365A Expired ES455365A1 (es) 1976-01-26 1977-01-26 Un metodo de preparacion de un peptido dotado de actividad biologica analoga a la de la morfina.

Country Status (11)

Country Link
JP (1) JPS5291839A (de)
CH (1) CH644352A5 (de)
DE (1) DE2703109A1 (de)
DK (1) DK33177A (de)
ES (1) ES455365A1 (de)
FI (1) FI70228C (de)
FR (1) FR2338925A1 (de)
HU (1) HU184704B (de)
IL (1) IL51332A (de)
NL (1) NL7700785A (de)
SE (1) SE7708404L (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4003000A (en) * 1975-05-27 1977-01-11 Sperry Rand Corporation Sinusoidal oscillator with electronically variable frequency
US4261888A (en) * 1976-04-12 1981-04-14 Sandoz Ltd. Organic compounds
FR2359817A1 (fr) * 1976-07-27 1978-02-24 Reckitt & Colmann Prod Ltd Nouveaux peptides, leur procede de preparation et composition therapeutique les contenant
AU2768977A (en) * 1976-08-09 1979-02-15 Searle & Co 1-substituted enkephalin derivatives
HU178001B (en) * 1976-09-16 1982-02-28 Gyogyszekutato Intezet Process for preparing new pentapeptides with morphine-like activity and derivatives thereof
DE2819277A1 (de) * 1977-05-16 1978-11-23 Sandoz Ag Neue polypeptidderivate, ihre herstellung und verwendung
GB2000784B (en) * 1977-07-05 1982-01-20 American Home Prod Analgesic polypetide
EP0000559B1 (de) * 1977-07-22 1983-10-05 The Wellcome Foundation Limited Pentapeptid-N-alkylamide und ihre Säureadditionssalze, Verfahren zur Herstellung dieser Verbindungen und ihre pharmakologischen Zusammensetzungen
US4264491A (en) * 1977-10-03 1981-04-28 Eli Lilly And Company Analgesic compounds
HU182051B (en) * 1978-05-02 1983-12-28 Takeda Chemical Industries Ltd Process for preparing tetrapeptide-hydrazyde derivatives
US4278596A (en) * 1978-08-08 1981-07-14 American Home Products Corporation Analgesic pentapeptides
CA1175810A (en) * 1979-03-30 1984-10-09 Frank A. Momany Synthetic peptides having pituitary growth hormone releasing activity
US4247543A (en) * 1979-04-09 1981-01-27 Sandoz Ltd. Organic compounds
US4396606A (en) * 1979-11-05 1983-08-02 Addiction Research Foundation Novel polypeptide analgesics
EP0044451B1 (de) * 1980-07-17 1984-04-18 Sandoz Ag Pentapeptide, Verfahren zu deren Herstellung, deren pharmazeutische Zusammensetzungen und deren Anwendung
FR2488253A1 (fr) * 1980-08-08 1982-02-12 Roques Bernard Nouveaux peptides et leur application en therapeutique
WO1983002272A1 (en) * 1981-12-28 1983-07-07 Beckman Instruments Inc Synthetic peptides having pituitary growth hormone releasing activity
US4491541A (en) * 1982-11-10 1985-01-01 Farmitalia Carlo Erba Peptides
JPH0680079B2 (ja) * 1984-11-09 1994-10-12 エーザイ株式会社 ポリペプチド
AU618029B2 (en) * 1987-11-02 1991-12-12 Imperial Chemical Industries Plc Polypeptide compounds
EP0644772B1 (de) * 1992-11-12 2003-04-02 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Opioidpeptide
AU2010236730B2 (en) * 2009-04-13 2012-09-20 Elc Management Llc Methionine sulfoxide peptide, compositions and methods of use
US10278957B2 (en) 2017-09-11 2019-05-07 Protagonist Therapeutics, Inc. Opioid agonist peptides and uses thereof

Also Published As

Publication number Publication date
FR2338925A1 (fr) 1977-08-19
DK33177A (da) 1977-07-27
HU184704B (en) 1984-10-29
SE7708404L (sv) 1977-07-27
IL51332A0 (en) 1977-03-31
DE2703109A1 (de) 1977-08-04
CH644352A5 (en) 1984-07-31
FI770254A7 (de) 1977-07-27
IL51332A (en) 1980-09-16
FI70228C (fi) 1986-09-15
FR2338925B1 (de) 1980-08-08
FI70228B (fi) 1986-02-28
JPS5291839A (en) 1977-08-02
NL7700785A (nl) 1977-07-28

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