ES455991A1 - Procedimiento para la obtencion de n-ciano-n'-metil-n"-(2- ((5-metil-1h-imidazol-4-yl)metil)tioetil)guanidina. - Google Patents
Procedimiento para la obtencion de n-ciano-n'-metil-n"-(2- ((5-metil-1h-imidazol-4-yl)metil)tioetil)guanidina.Info
- Publication number
- ES455991A1 ES455991A1 ES455991A ES455991A ES455991A1 ES 455991 A1 ES455991 A1 ES 455991A1 ES 455991 A ES455991 A ES 455991A ES 455991 A ES455991 A ES 455991A ES 455991 A1 ES455991 A1 ES 455991A1
- Authority
- ES
- Spain
- Prior art keywords
- methyl
- guanidine
- cyano
- thioethyl
- imidazol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 5
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- QSJXEFYPDANLFS-UHFFFAOYSA-N Diacetyl Chemical compound CC(=O)C(C)=O QSJXEFYPDANLFS-UHFFFAOYSA-N 0.000 abstract 2
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 abstract 2
- HOJZUQSKSVMXON-UHFFFAOYSA-N 1-bromobutane-2,3-dione Chemical compound CC(=O)C(=O)CBr HOJZUQSKSVMXON-UHFFFAOYSA-N 0.000 abstract 1
- -1 5-methyl-1H-imidazol-4-yl Chemical group 0.000 abstract 1
- PNKUSGQVOMIXLU-UHFFFAOYSA-N Formamidine Chemical compound NC=N PNKUSGQVOMIXLU-UHFFFAOYSA-N 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 238000007796 conventional method Methods 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000012429 reaction media Substances 0.000 abstract 1
- 125000004014 thioethyl group Chemical group [H]SC([H])([H])C([H])([H])* 0.000 abstract 1
- 150000003573 thiols Chemical group 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Procedimiento para la obtención de N-ciano-N''-metil-N"-[2-[(5-metil-1H-imidazol-4-yl)metil]tioletil] guanidina, caracterizado porque se hace reaccionar un compuesto de fórmula general: **(Fórmula)** con otro compuesto de fórmula general P-S-CH2-CH2NH2 (2) en la que P es un átomo de hidrógeno o un grupo protector de tioles, para obtener la N-ciano-N''-metil-N"-(2-etanotiol) guanidina (3), que a su vez se hace reaccionar con la 1-bromo-2, 3-butanodiona (4) para obtener la N-ciano-N''-metil-N"-[2-(2,3-butanodiona) tioetil]guanidina (5) que tratado con formamidina o con una solución acuosa concentrada de amoníaco y formaldehído genera el producto (6) deseado que se aisla del medio reaccional por los métodos convencionales.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES455991A ES455991A1 (es) | 1977-02-17 | 1977-02-17 | Procedimiento para la obtencion de n-ciano-n'-metil-n"-(2- ((5-metil-1h-imidazol-4-yl)metil)tioetil)guanidina. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES455991A ES455991A1 (es) | 1977-02-17 | 1977-02-17 | Procedimiento para la obtencion de n-ciano-n'-metil-n"-(2- ((5-metil-1h-imidazol-4-yl)metil)tioetil)guanidina. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES455991A1 true ES455991A1 (es) | 1978-02-16 |
Family
ID=8473165
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES455991A Expired ES455991A1 (es) | 1977-02-17 | 1977-02-17 | Procedimiento para la obtencion de n-ciano-n'-metil-n"-(2- ((5-metil-1h-imidazol-4-yl)metil)tioetil)guanidina. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES455991A1 (es) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0259140A1 (en) * | 1986-09-01 | 1988-03-09 | Mitsui Petrochemical Industries, Ltd. | Cyanoguanidine derivative and process for preparation thereof |
-
1977
- 1977-02-17 ES ES455991A patent/ES455991A1/es not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0259140A1 (en) * | 1986-09-01 | 1988-03-09 | Mitsui Petrochemical Industries, Ltd. | Cyanoguanidine derivative and process for preparation thereof |
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