ES458428A1 - Un procedimiento para la preparacion de nuevos derivados de 9-aminoalquil-9,10 dihidro-9,10-metanoantraceno. - Google Patents

Un procedimiento para la preparacion de nuevos derivados de 9-aminoalquil-9,10 dihidro-9,10-metanoantraceno.

Info

Publication number
ES458428A1
ES458428A1 ES77458428A ES458428A ES458428A1 ES 458428 A1 ES458428 A1 ES 458428A1 ES 77458428 A ES77458428 A ES 77458428A ES 458428 A ES458428 A ES 458428A ES 458428 A1 ES458428 A1 ES 458428A1
Authority
ES
Spain
Prior art keywords
alkyl
formula
heterocyclic ring
adjacent nitrogen
tricyclic compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES77458428A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP14373474A external-priority patent/JPS5170760A/ja
Priority claimed from JP752909A external-priority patent/JPS585182B2/ja
Priority claimed from JP4145275A external-priority patent/JPS5821904B2/ja
Priority claimed from JP8387175A external-priority patent/JPS5911576B2/ja
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Publication of ES458428A1 publication Critical patent/ES458428A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/235—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/235—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings
    • C07C47/238—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings having unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/38—Unsaturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings
    • C07C47/453—Unsaturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
    • C07C57/50—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/16—Unsaturated compounds
    • C07C61/39—Unsaturated compounds containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Nuevos 9-aminoalquil-metanoantracenos de fórmula **fórmula** donde A es alquileno C1-C4 o alquenileno C3-C4 y R1 y R2 son cada uno de ellos hidrógeno, alquilo C1-C4, alquenilo C3-C4, alquinilo C3-C4, cicloalquil (C3-C6) alquilo C1-C3, aralquilo C1-C3 o polihaloalquilo C1-C4 o , cuando se toman junto con el átomo de nitrógeno adyacente, pueden formar un anillo heterocíclico nitrógeno adyacente, pueden formar un anillo heterocíclico nitrogenado de 5 a 7 miembros que puede contener un hetero átomo adicional y sus sales no tóxicas , que son útiles como drogas ansiolíticas ,antidepresoras, tranquilizantes mayores, antihistamínicas y antialérgicas y pueden ser preparados a través de un nuevo compuesto intermedio clave, a saber el 9-formil-9,10- dihidro-9,10-metanoantraceno, por diversos métodos
ES77458428A 1974-12-13 1977-05-02 Un procedimiento para la preparacion de nuevos derivados de 9-aminoalquil-9,10 dihidro-9,10-metanoantraceno. Expired ES458428A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP14373474A JPS5170760A (ja) 1974-12-13 1974-12-13 Metanooantorasenjudotaino shinkiseizoho
JP752909A JPS585182B2 (ja) 1974-12-27 1974-12-27 シンキナメタノ−アントラセンユウドウタイノ セイゾウホウ
JP4145275A JPS5821904B2 (ja) 1975-04-04 1975-04-04 シンキナメタノ−アントラセンユウドウタイノセイゾウホウホウ
JP8387175A JPS5911576B2 (ja) 1975-07-07 1975-07-07 新規なメタノ−アントラセン誘導体の製造法

Publications (1)

Publication Number Publication Date
ES458428A1 true ES458428A1 (es) 1978-12-16

Family

ID=27453741

Family Applications (3)

Application Number Title Priority Date Filing Date
ES75443487A Expired ES443487A1 (es) 1974-12-13 1975-12-13 Un procedimiento para la preparacion de nuevos derivados de 9-aminoalquil-9, 10-dibidro 9, 10-metanoantroceno.
ES77458428A Expired ES458428A1 (es) 1974-12-13 1977-05-02 Un procedimiento para la preparacion de nuevos derivados de 9-aminoalquil-9,10 dihidro-9,10-metanoantraceno.
ES77458426A Expired ES458426A1 (es) 1974-12-13 1977-05-02 Un procedimiento para la preparacion de 9-formil-9,10-dihi- dro-9-10-metanoantraceno.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES75443487A Expired ES443487A1 (es) 1974-12-13 1975-12-13 Un procedimiento para la preparacion de nuevos derivados de 9-aminoalquil-9, 10-dibidro 9, 10-metanoantroceno.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES77458426A Expired ES458426A1 (es) 1974-12-13 1977-05-02 Un procedimiento para la preparacion de 9-formil-9,10-dihi- dro-9-10-metanoantraceno.

Country Status (13)

Country Link
US (1) US4224344A (es)
AR (2) AR212586A1 (es)
BE (1) BE836599A (es)
CA (2) CA1061787A (es)
CH (1) CH617920A5 (es)
DE (1) DE2556143A1 (es)
ES (3) ES443487A1 (es)
FR (2) FR2293940A1 (es)
GB (1) GB1508669A (es)
NL (1) NL7514601A (es)
NO (1) NO792908L (es)
NZ (1) NZ179530A (es)
SE (2) SE429040B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9216297D0 (en) * 1991-08-15 1992-09-16 Ici Plc Therapeutic agents
GB9117639D0 (en) * 1991-08-15 1991-10-02 Ici Plc Therapeutic compounds
GB9216298D0 (en) * 1991-08-15 1992-09-16 Ici Plc Piperidine derivatives
US5512575A (en) * 1991-08-15 1996-04-30 Zeneca Limited Methanoanthraceneyl methyl piperidinyl compounds
ZA200804550B (en) 2005-11-09 2009-08-26 Combinatorx Inc Methods, compositions, and kits for the treatment of medical conditions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE674185A (es) * 1961-10-10
US3622630A (en) * 1968-07-03 1971-11-23 Smith Kline French Lab 10-aminoalkyl-9,10-dihydroanthracenes
US3708525A (en) * 1969-11-20 1973-01-02 Merck & Co Inc Chemical compounds and processes for preparing same
IL38772A (en) * 1971-02-23 1975-06-25 Ciba Geigy Ag Aminopropenyl-anthracene derivatives,their manufacture and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
ES458426A1 (es) 1978-04-01
CH617920A5 (es) 1980-06-30
NZ179530A (en) 1978-04-28
CA1061787A (en) 1979-09-04
AR213412A1 (es) 1979-01-31
ES443487A1 (es) 1977-11-01
BE836599A (fr) 1976-06-14
NO792908L (no) 1976-06-15
NL7514601A (nl) 1976-06-15
FR2293940A1 (fr) 1976-07-09
DE2556143A1 (de) 1976-06-16
FR2308610B1 (es) 1979-06-29
SE7514077L (sv) 1976-06-14
FR2293940B1 (es) 1981-12-04
GB1508669A (en) 1978-04-26
US4224344A (en) 1980-09-23
AR212586A1 (es) 1978-08-15
FR2308610A1 (fr) 1976-11-19
SE429040B (sv) 1983-08-08
CA1052393A (en) 1979-04-10
SE7907050L (sv) 1979-08-23
AU8741075A (en) 1977-06-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19841121