ES459422A1 - Un procedimiento de preparacion de 3-enoleteres de 11 beta- hidroxi-a4-pregnen-3-onas y sus derivados. - Google Patents

Un procedimiento de preparacion de 3-enoleteres de 11 beta- hidroxi-a4-pregnen-3-onas y sus derivados.

Info

Publication number
ES459422A1
ES459422A1 ES459422A ES459422A ES459422A1 ES 459422 A1 ES459422 A1 ES 459422A1 ES 459422 A ES459422 A ES 459422A ES 459422 A ES459422 A ES 459422A ES 459422 A1 ES459422 A1 ES 459422A1
Authority
ES
Spain
Prior art keywords
pregnen
procedure
preparation
derivatives
enoleteres
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES459422A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of ES459422A1 publication Critical patent/ES459422A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Un procedimiento de preparación de 3-enoléteres de 11beta-hidroxi-delta4-pregnen-3-onas y sus derivados que consisten en (* ver imagen) (a) hacer reaccionar un compesto de 6alfa-halo-11beta-hidroxipregn-4-en-3,20-diona de fórmula; (b) hacer reaccionar dicho 3-enoléter del paso (a) con 2,3-dicloro-4,5-dicianobenzoquinona en diaoxano; (c) opcionalmente, trans-esterificar el producto del paso (b) para formar la 6-halo-11beta, 17alfa, 21-trihidroxipregna-1,4,6-trien-3,20-diona.
ES459422A 1975-02-18 1977-06-02 Un procedimiento de preparacion de 3-enoleteres de 11 beta- hidroxi-a4-pregnen-3-onas y sus derivados. Expired ES459422A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/550,245 US3956349A (en) 1975-02-18 1975-02-18 Process for preparing 3-enol ethers of 11β-hydroxy-Δ4 -pregnene-3-ones and derivatives thereof

Publications (1)

Publication Number Publication Date
ES459422A1 true ES459422A1 (es) 1978-04-01

Family

ID=24196322

Family Applications (2)

Application Number Title Priority Date Filing Date
ES445303A Expired ES445303A1 (es) 1975-02-18 1976-02-18 Un procedimiento para preparar 3-enoleteres de 11 beta- hidroxi-delta cuatro-pregnen-3-onas y derivados.
ES459422A Expired ES459422A1 (es) 1975-02-18 1977-06-02 Un procedimiento de preparacion de 3-enoleteres de 11 beta- hidroxi-a4-pregnen-3-onas y sus derivados.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES445303A Expired ES445303A1 (es) 1975-02-18 1976-02-18 Un procedimiento para preparar 3-enoleteres de 11 beta- hidroxi-delta cuatro-pregnen-3-onas y derivados.

Country Status (17)

Country Link
US (1) US3956349A (es)
JP (2) JPS51143655A (es)
AU (1) AU503544B2 (es)
CA (1) CA1067066A (es)
CH (3) CH623598A5 (es)
DE (2) DE2660849C2 (es)
DK (1) DK142725B (es)
ES (2) ES445303A1 (es)
FI (1) FI54713C (es)
FR (3) FR2301263A1 (es)
GB (1) GB1513211A (es)
IE (1) IE43654B1 (es)
IL (1) IL48852A (es)
IT (1) IT1057213B (es)
NL (1) NL183461C (es)
NZ (1) NZ179952A (es)
SE (3) SE417827B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3100462A (en) * 1959-03-11 1963-08-13 Silver Corp Seed planting apparatus
US6222762B1 (en) 1992-01-14 2001-04-24 Sandisk Corporation Multi-state memory
DE4433374A1 (de) * 1994-09-20 1996-03-21 Hoechst Ag 17-Desoxi-corticosteroid-21-/O/-Carbonsäure- ester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB890835A (en) * 1957-06-22 1962-03-07 Syntex Sa New cyclopentanophenanthrene derivatives and processes for the production thereof
US3232965A (en) * 1958-06-20 1966-02-01 Syntex Corp 6-chloro-delta1,4,6-pregnatriene-17alpha, 21-diol-3,20-diones
CH390243A (de) * 1959-08-26 1965-04-15 Merck Ag E Verfahren zur Herstellung von ungesättigten Halogensteroiden
US3082224A (en) * 1960-11-18 1963-03-19 Merck & Co Inc Novel 16alpha-methyl-3, 5-pregnadienes and processes
US3087927A (en) * 1961-07-07 1963-04-30 American Cyanamid Co Method of preparing 21-sulfonated steroids of the pregnane series

Also Published As

Publication number Publication date
FR2308640B1 (es) 1978-12-22
CH628642A5 (de) 1982-03-15
IE43654L (en) 1976-08-18
DE2606299A1 (de) 1976-09-09
NL7601223A (nl) 1976-08-20
FI760274A7 (es) 1976-08-19
NL183461C (nl) 1988-11-01
IT1057213B (it) 1982-03-10
FR2301263A1 (fr) 1976-09-17
FI54713C (fi) 1979-02-12
NZ179952A (en) 1978-04-03
IE43654B1 (en) 1981-04-22
AU503544B2 (en) 1979-09-06
JPS6310159B2 (es) 1988-03-04
JPH02360B2 (es) 1990-01-08
GB1513211A (en) 1978-06-07
SE8205170L (sv) 1982-09-10
CH624685A5 (es) 1981-08-14
FI54713B (fi) 1978-10-31
DE2606299C2 (de) 1984-08-30
IL48852A (en) 1979-01-31
CH623598A5 (es) 1981-06-15
JPS61267598A (ja) 1986-11-27
FR2308641B1 (es) 1978-12-22
DE2660849C2 (de) 1985-11-07
ES445303A1 (es) 1977-10-01
FR2308641A1 (fr) 1976-11-19
DK67776A (es) 1976-08-19
DK142725C (es) 1981-08-24
DK142725B (da) 1981-01-05
SE435388B (sv) 1984-09-24
SE8205170D0 (sv) 1982-09-10
NL183461B (nl) 1988-06-01
SE417827B (sv) 1981-04-13
SE437160B (sv) 1985-02-11
FR2301263B1 (es) 1978-12-15
JPS51143655A (en) 1976-12-10
US3956349A (en) 1976-05-11
SE7905861L (sv) 1979-07-04
IL48852A0 (en) 1976-03-31
AU1081776A (en) 1977-08-11
FR2308640A1 (fr) 1976-11-19
SE7601753L (sv) 1976-08-19
CA1067066A (en) 1979-11-27

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980202